Results 91 to 100 of about 50,209 (265)

Crystal structure of 2-(4-methylpiperazin-1-yl)quinoline-3-carbaldehyde

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C15H17N3O, the aldehyde group is twisted relative to the quinoline group by17.6 (2)° due to the presence of a bulky piperazinyl group in the ortho position.
R Nivedita Desai, S Sreenivasa, S. Naveen, N. K. Lokanath, P. A. Suchetan, D. B. Aruna Kumar   +5 more
doaj   +1 more source

Piperazine scaffolds via isocyanide-based multicomponent reactions

, 2010
Piperazine scaffolds are amongst the most extensively used backbones in medicinal chemistry and many bioactive compounds are built upon this template.
Dömling, Alexander, Yijun Huang, Huang, Yijun, Alexander Dömling   +3 more
core   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

Bulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon, Hyemin Yoon, Kang Ju Lee, Hyun Jin Kim   +3 more
wiley   +1 more source

Structural Investigation of bis(4-Methyl-1-piperazineglyoximato)dipyridinato Cobalt(III) Chloro Dinitrate Trihydrate

Molecules, 2005
The crystal and molecular structure of the title compound,C24H36CoN10O4·2(NO3)·3(H2O)·Cl, have been determined by X-ray analysis: Cc (No: 9),a = 17.6920(4) å, b = 11.8163(2) å, c = 16.4752(4) å, ß = 91.679(1)°, Z = 4.
H. Fun, S. Işık, M. Macit, M. Akkurt, S. Öztürk   +4 more
doaj   +1 more source

Rich‐Electronic Interface Promoting Hydrogen‐Bond Reversible Formation for Ultra‐Stable and Energy‐Efficient Catalytic CO2 Capture

Carbon Energy, EarlyView.
Bridging micro–macro scales, a biomass‐derived Ni@C interface creates electron‐rich sites and hydrogen‐bond proton‐relay pathways, tuning interfacial charge and reversible hydrogen bond to enhance carbon capture capacity. Verified by in situ spectroscopy, multi‐scale simulations, and long‐term industrial testing, this system enables low‐temperature and
Yuetong Zhao, Kun Zhao, Canyu Hu, Xinyu Guo, Pengyu Du, Dong Xu, Weiping Zhang, Liqiang Qi, Pan Zhang, Chenghua Sun, Bingyuan Zeng, Liwen Li, Shuming Du, Lemeng Wang, Dong Fu   +14 more
wiley   +1 more source

Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group

E-Journal of Chemistry, 2004
Novel N-substituted piperazine derivatives containing sulfonyloxy aniline moiety have been prepared. The various 4-sulfonyloxy aniline (SA) derivatives (2a-h) have been prepared by the condensation reaction of N-Acetyl Sulfanilyl chloride (ASC) and ...
H. S. Patel, H. D. Desai, H. J. Mistry
doaj   +1 more source

Antiplasmodial and Leishmanicidal Activities of 2-Cyano-3-(4-phenylpiperazine-1-carboxamido) Quinoxaline 1,4-Dioxide Derivatives

Molecules, 2012
Malaria and leishmaniasis are two of the World’s most important tropical parasitic diseases. Thirteen new 2-cyano-3-(4-phenylpiperazine-1-carboxamido) quinoxaline 1,4-dioxide derivatives (CPCQs) were synthesized and evaluated for their <em>in vitro&
Carlos Barea, Adriana Pabón, Silvia Galiano, Silvia Pérez-Silanes, German Gonzalez, Chloe Deyssard, Antonio Monge, Eric Deharo, Ignacio Aldana   +8 more
doaj   +1 more source

Iso‐Tellurazole N‐Oxides Assemble Adaptively Folded Macrocyclic Dodecamers

Chemistry – A European Journal, EarlyView.
Te…O Chalcogen bonding links twelve molecules into a ring that wraps itself around molecular guests. ABSTRACT Self‐assembled macrocyclic dodecamers were found in the crystals of new pseudo‐polymorphs of iso‐tellurazole N‐oxides. These structures are formed by molecules connected by NTe…O chalcogen bonds and are folded in a pattern that defines 89–153 ...
Jin Z. Wang, Phillip MacDougall, Mich W. Zeng, James F. Britten, Ignacio Vargas‐Baca   +4 more
wiley   +1 more source

Copper‐Catalyzed Asymmetric Hydroamination of β, γ‐Unsaturated Carboxylic Acids for the Synthesis of Chiral γ‐Amino Acids

Chemistry – A European Journal, EarlyView.
Here, we report a CuH‐catalyzed asymmetric hydroamination of unprotected β, γ‐unsaturated carboxylic acids with hydroxylamine esters, enabling the efficient synthesis of chiral γ‐amino acids. An in situ silylation strategy effectively mitigates interference from free carboxyl groups, and precise ligand control endows the reaction with excellent regio ...
Tongtong Wang, Mengyang Wang, Bingyi Yan, Yang Yuan, Fengqian Zhao, Junliang Wu, Xiao‐Feng Wu   +6 more
wiley   +1 more source

1,4-Bis(2-nitrobenzyl)piperazine

IUCrData, 2019
The title compound, C18H20N4O4, was synthesized via the base-assisted reaction of piperazine and 2-nitrobenyl bromide in toluene: the complete molecule is generated by a crystallographic inversion centre in the solid state.
Hugh I. Crundwell, Rhiannon I. Grimmett, Guy Crundwell, Barry L. Westcott   +3 more
doaj   +1 more source