Results 101 to 110 of about 45,771 (255)

Synthesis and Therapeutic activity of some new piperazine Derivatives

, 2010
Not ...
Savaliya, Mahendra D.
core  

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü, Münevver Baran, Miyase Gözde Gündüz, Şengül Dilem Doğan   +3 more
wiley   +1 more source

Synthesis and characterization of Fe(III)-piperazine-derived complexes encapsulated in zeolite Y

Química Nova, 2012
Zeolite-encapsulated complexes have been widely applied in hydrocarbon oxidation catalysis. The "ship-in-a-bottle" encapsulation of iron(III) complexes containing piperazine and piperazine-derivative ligands in zeolite-Y is described. The flexible ligand
Márcio E. Berezuk, Andrea Paesano Jr., Nakédia M. F. Carvalho, Adolfo Horn Jr., Pedro A. Arroyo, Lúcio Cardozo-Filho   +5 more
doaj   +1 more source

On the Assembly of Actin Polymerization‐Powered Motors

Macromolecular Rapid Communications, EarlyView.
Actin polymerization‐powered motors have the highest speed when the actin recruiting‐polymerizing proteins are immobilized in polymer brushes on their surface. These motors orbit around larger tracer particles at pH above the isoelectric point of ActA but dock onto the tracer particles’ surface at lower pH. ABSTRACT Nano‐ and micromotors are a class of
Miguel A. Ramos Docampo, Cathrine Abild Meyer, Brigitte Städler   +2 more
wiley   +1 more source

Piperazine-Linked Covalent Triazine Polymer as an Efficient Platform for the Removal of Toxic Mercury(II) Ions from Wastewater

A piperazine-linked robust N-rich covalent organic polymer (COP), SMCOP-1, was synthesized by a catalyst-free method and characterized by Fourier transform infrared (FTIR), 13C CP/MAS, X-ray photoelectron spectroscopy (XPS), and powder X-ray diffraction (
Argha Chakraborty (11560209), Probal Nag (9862273), Sayantan Sarkar (11975699), Suman Mukhopadhyay (190415), Sivaranjana Reddy Vennapusa (9862276), Reena Kyarikwal (11786245)   +5 more
core   +1 more source

Revisiting the Association Between Calcium Channel Blockers and Parkinson's Disease in the E3N Cohort

Movement Disorders, EarlyView.
Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard, Agnès Fournier, Émeline Courtois, Fanny Artaud, Pascale Tubert‐Bitter, Emmanuel Roze, Ismaïl Ahmed, Anne C.M. Thiébaut, Alexis Elbaz, Thi Thu Ha Nguyen   +9 more
wiley   +1 more source

Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. II. Discovery of 1-[(2,4-Dimethyl-3-pyridinyl)carbonyl]-4- methyl-4-[3(S)-methyl-4-[1(S)-[4-(trifluoro- methyl)phenyl]ethyl]-1-piperazinyl]- piperidine N1-Oxide (Sch-350634), an Orally Bioavailable, Potent CCR5 Antagonist

, 2016
Truncation of the original piperidino-2(S)-methyl piperazine lead structure 2, from a family of muscarinic antagonists, gave compound 8 which has improved selectivity for the HIV-1 co-receptor CCR5 over muscarinic receptors.
Serena Xu (2660917), Jayaram R. Tagat (2276683), Ruo W. Steensma (2718049), Michael G. Murray (2174420), Kathleen Cox (2026282), Sue-Ing Lin (2124574), Julie M. Strizki (2718031), Dennis V. Nazareno (3014244), Bernard R. Neustadt (3014247), Lisa Wojcik (3014241), Nicole Vantuno (3014238), Bahige M. Baroudy (2718034), Stuart W. McCombie (2718040)   +12 more
core   +1 more source

Cefdinir reprograms Gram‐positive bacteria to synergize with lysozyme against superbugs

mLife, EarlyView.
Abstract Multidrug‐resistant (MDR) bacteria pose a critical global health threat, urgently requiring solutions. Cefdinir, the highest‐selling third‐generation cephalosporin but one now facing clinical obsolescence due to escalating resistance, is conventionally classified as a nascent cell wall synthesis inhibitor.
Qi Zhang, Yang Yang, Shuqi Li, Zhao Liu, Chun‐Kit Lee, Chi‐Bun Ko, Qian Zhao   +6 more
wiley   +1 more source

Piperazine Abuse and Psychosis: A Systematic Review of the Literature

Psychiatry International
Background: Piperazines, synthetic compounds known for their stimulant and hallucinogenic effects, have gained prominence among novel psychoactive substances (NPS) and are frequently associated with adverse psychiatric outcomes, including psychosis ...
Alessio Mosca, Stefania Chiappini, Andrea Miuli, Gianluca Mancusi, Clara Cavallotto, John M. Corkery, Livia Miotti, Mauro Pettorruso, Giovanni Martinotti, Fabrizio Schifano   +9 more
doaj   +1 more source

Thermal Degradation of Piperazine Blends with Diamines

, 2013
Concentrated, aqueous piperazine (PZ) has been developed as an attractive solvent for use in CO2 capture for coal- fired power plants because of its low degradation rate, high CO2 capacity, and high CO2 absorption rate, but its use may be limited by ...
Namjoshi, Omkar, Li, Le, Rochelle, Gary, Du, Yang   +3 more
core   +1 more source