Results 121 to 130 of about 50,209 (265)

New antiplasmodial piperazine alkaloid derivatives from Rauvolfia mannii Stapf. (Apocynaceae)

International audienceThe stem bark extract of Rauvolfia mannii (Apocynaceae) was submitted to chemical and antiparasitic investigations. Chemical analyses resulted in the isolation of two new furyl-piperazine alkaloid derivatives namely 2-(2 ...
Ferron, Solenn, Pegnyemb, Dieudonné, Emmanuel, Ntomi Djipmegne, Daniela, Kinyok, Mc Jesus, Tomasi, Sophie, Néhémie Bitombo, André, Abouem À Zintchem, Auguste, Ngono Bikobo, Dominique, Serge   +7 more
core   +1 more source

Solid-phase synthesis of libraries generated from a 4-phenyl-2-carboxy-piperazine Scaffold

, 2001
Strategies for finding novel structures of therapeutical interest are discussed. The rationale for the selection of the two scaffolds N4-(m-aminophenyl)-piperazine-2-carboxylic acid E and N4-(o-aminophenyl)-piperazine-2-carboxylic F is described.
Nilsson, Jonas W.,, Thorstensson, Fredrik,, Kvarnström, Ingemar,, Nilsson, Ingemar, Samuelsson, Bertil,, Oprea, Tudor,   +5 more
core   +1 more source

Controlling Linear and Non‐Linear Mechanics in Multicomponent Hydrogels Through Programmable Supramolecular and Covalent Interactions

Journal of Polymer Science, EarlyView.
Fully synthetic, multi‐component hydrogels are engineered that possess tunable (non)‐linear mechanics by programmable supramolecular and covalent interactions. By changing the type of inter‐network interaction, the linear and non‐linear mechanics of the macroscopic hydrogel were programmed.
Martin G. T. A. Rutten, Laura Rijns, Jingyi Huang, Ruth Cardinaels, Paul H. J. Kouwer, Patricia Y. W. Dankers   +5 more
wiley   +1 more source

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

ChemistryOpen
Interest in piperazine scaffolds continues to rise due to their broad relevance across anti‐infective, anticancer, and neuroactive research. This review examines reports published from 2014 to 2024 and organizes current developments by therapeutic class,
Assel Ten, Raushan Koizhaiganova, Dilnaz Bissenbay, Bagila Tursynova, Zhanar Zhaxibayeva, Valentina Yu   +5 more
doaj   +1 more source

Endophytic fungi from two isolated Bethencourtia palmensis populations: metabolomic and bioactivity fingerprinting

Pest Management Science, EarlyView.
We compared two island populations of Bethencourtia palmensis and their culturable endophytic fungi, revealing distinct plant chemistries and a higher biopesticidal potential in the endophytic fungi from La Palma population along with high potential for the discovery of novel compounds.
Jorge Rojas López‐Menchero, Juan Imperial, Carmen Elisa Díaz, María Fe Andrés, Azucena González‐Coloma   +4 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Piperazine Bridged Resorcinarene Cages

, 2016
The one-pot Mannich condensation of resorcinarenes with piperazine and an excess of formaldehyde under high dilution conditions results in a helical cage, namely, a covalently linked dimer of two resorcinarenes connected via four piperazine bridges in ...
Kari Rissanen (1282326), N. Kodiah Beyeh (1711417), Arto Valkonen (1889257)   +2 more
core   +1 more source

Efficient water‐soluble blue/red‐emissive carbon dots matching plant absorption spectra: Synthesis, tunable control, and their applications in promoting plant growth

Responsive Materials, EarlyView.
Guided by the spectral demand of plant photosystems, this review summarizes the synthesis, emission regulation, dual‐emission design, and gram‐scale production of CDs for agricultural applications. Spectrally matched blue‐ and red‐emissive CDs enhance plant light utilization by converting underutilized light into photosynthetically active radiation and
Yijing Chen, Ziyue Mu, Haoran Zhang, Xuejie Zhang, Wei Li, Bingfu Lei   +5 more
wiley   +1 more source

Mixed TiO2–SiO2 thin coatings for selective adsorption and sunlight‐powered photodegradation of cationic pollutants

Responsive Materials, EarlyView.
Environmental pollution and water scarcity demand innovative purification methods. This study presents a sol‐gel approach to fabricate mixed silica–titania thin films joining photocatalytic activity with selective sorption capability. The films exhibit higher surface area, enhanced degradation of cationic and improved performance over bare titania ...
Andrea Lanfranchi, Simone Bertucci, Margherita Peragallo, Fabiano Martorelli, Giovanni Manfredi, Davide Avanzino, Roberto Spotorno, Stefano Alberti, Davide Comoretto, Francesco Di Stasio, Maddalena Patrini, Federico Locardi, Mirko Prato, Paola Lova   +13 more
wiley   +1 more source

Surface‐Functionalized Poly(2‐Oxazoline)‐Based Grids Produced by Two‐Photon Polymerization as 3D‐Structured Hydrogels Promoting Cell Adhesion

Small, EarlyView.
Sidechain‐functionalized poly(2‐oxazoline) cross‐linkers were utilized to print grids with varying mesh sizes by two‐photon polymerization (2PP grids). The amino‐functionalized hydrogels were subsequently used to covalently couple the RGD‐containing peptide sequence GCWRGDSP (RGD) to the amino groups in the side chains. In cell adhesion tests with L929
Tim Hoffmann, David Pretzel, Steffi Stumpf, Lena‐Marie Kaspar, Florian Behrendt, Christiane Höppener, Aaron Reupert, Volker Deckert, Lothar Wondraczek, Michael Gottschaldt, Klaus Liefeith, Ulrich S. Schubert   +11 more
wiley   +1 more source