Results 141 to 150 of about 50,209 (265)

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Thermo‐tone: A newly revealed mechanism of blood flow regulation

Experimental Physiology, EarlyView.
Abstract Myogenic tone enables dynamic control of tissue blood flow. This intrinsic property of vascular smooth muscle cells to sense stretch and reflexively adjust the calibre of small arteries is crucial to maintain capillary pressure and a blood flow reserve. For over 120 years blood pressure was considered the sole determinant of myogenic tone. Our
Thieu X. Phan, Gerard P. Ahern
wiley   +1 more source

Electrophysiological properties of the dorsal motor nucleus of the vagus motoneurones controlling airway mucus secretion in rats

The Journal of Physiology, EarlyView.
Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza, Renato W. Martins Sá, Luiza Henrique de Souza, Fernando S. Ramalho, Davi J. A. Moraes   +4 more
wiley   +1 more source

Thiolane Sulfoximines as Azide Surrogates for Quinolyl Nitrenes: Photochemical Access to Ortho‐Diaminoquinolines

Advanced Synthesis &Catalysis, Volume 368, Issue 21, 3 November 2026.
Thiolane sulfoximines provide practical and safer surrogates for hazardous azides in nitrene photochemistry, enabling direct access to 7,8‐diaminoquinolines and fused δ‐lactams. DFT calculations support the reaction mechanism and rationalize product selectivity.
Lorenzo Serusi, Timothé Maujean, Camille Van Wesemael, Romain Pertschi, Vicenç Branchadell, Mihaela Gulea   +5 more
wiley   +1 more source

Piperazine-Linked Covalent Triazine Polymer as an Efficient Platform for the Removal of Toxic Mercury(II) Ions from Wastewater

A piperazine-linked robust N-rich covalent organic polymer (COP), SMCOP-1, was synthesized by a catalyst-free method and characterized by Fourier transform infrared (FTIR), 13C CP/MAS, X-ray photoelectron spectroscopy (XPS), and powder X-ray diffraction (
Argha Chakraborty (11560209), Probal Nag (9862273), Sayantan Sarkar (11975699), Suman Mukhopadhyay (190415), Sivaranjana Reddy Vennapusa (9862276), Reena Kyarikwal (11786245)   +5 more
core   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Nucleophilic Aromatic Substitution in the Gas Phase

Journal of Physical Organic Chemistry, Volume 39, Issue 11, November 2026.
In this review, we highlight experimental studies of gas‐phase SNAr. Studying reactions in the gas phase provides invaluable information on intrinsic reactivity by eliminating the complications of solvent effects. Because SNAr is a fundamental reaction in chemical research and organic synthesis, understanding its underlying reactivity and mechanisms is
Daniel N. Hirsch, Damon J. Hinz, Jeehiun K. Lee   +2 more
wiley   +1 more source

In vitro toxicity of piperazine-derived designer drugs in differentiated neural cell lines

Piperazine derivatives are common ingredients in recreational “party pills” which are used to provide a stimulant, euphoric effect akin to that of methylenedioxymethamphetamine (MDMA, “ecstasy”).
Stig O.P., Jacobsson,, Popova, Dina,
core  

Design, Synthesis and Biophysical Characterisation of CPP‐PNA Conjugates for Targeting Oncogenic microRNA‐221

Journal of Peptide Science, Volume 32, Issue 11, November 2026.
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo, Françoise Illien, Fabienne Burlina, Barbara Biondi   +3 more
wiley   +1 more source

Synergistic Defect Passivation and Phase Separation Suppression for Efficient Wide‐Bandgap Perovskite and Tandem Photovoltaics

Rare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Wide‐bandgap perovskite solar cells (WBG PSCs) have attracted significant attention as the top cell in tandem perovskite solar cells. However, the complexity of the composition leads to challenges such as defect formation and phase separation during the crystallization process, which impose significant constraints on the power conversion ...
Suzhen Liu, Wenye Jiang, Binglan Xiong, Sen Jiang, Yingjie Zhu, Yuexin Lin, Wenhan Yang, Tian Zhao, Nan Zhang, Chao Liang   +9 more
wiley   +1 more source