Results 141 to 150 of about 97,443 (299)
ChemistryOpen, Volume 15, Issue 5, May 2026.This review examines how hybrid modification strategies enhance the structural design and environmental performance of metal–organic frameworks (MOFs). It outlines key synthesis routes, functionalization approaches, and integration with complementary materials, highlighting advances in pollutant removal, sensing, and sustainable remediation.
Samar H. Elagamy +3 more
wiley +1 more source
AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives
Journal of Integrative Plant Biology, Volume 68, Issue 5, Page 1384-1398, May 2026.The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li +5 more
wiley +1 more source
Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 3, May 2026.ABSTRACT Background/Purpose The UVB and UVA components of terrestrial solar ultraviolet radiation (UVR) cause acute and chronic damage to skin. These adverse effects can be reduced by sunscreen application. The sun protection factor (SPF) is primarily a measure of UVB protection against erythema and does not quantify protection from UVA, which is the ...
Antony Young +9 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 16, 13 April 2026.A novel carbon dots material (BUL‐CDs) with an initial afterglow brightness (406 cd m−2) far exceeding that of other afterglow luminescent materials was developed. Furthermore, the BUL‐CDs exhibited time‐dependent afterglow colors, excitation‐dependent afterglow colors, and thermochromic afterglow in response to triplet variables.
Yupeng Liu +13 more
wiley +2 more sources
Rapid Communications in Mass Spectrometry, Volume 40, Issue 8, 30 April 2026.ABSTRACT Background Proteolytic processing is a fundamental post‐translational modification. Liquid chromatography–tandem mass spectrometry (LC–MS/MS) workflows are powerful for degradomic analyses but inherently sacrifice spatial information, a critical aspect for investigating biological systems such as aberrant extracellular matrix remodeling and ...
Mujia Jenny Li +8 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.The purification protocol for hypertrophied hepatic stellate cells (hypHSCs) developed in this study, using fibrotic and steatotic mouse livers (CDAHFD model), made it possible to obtain a high‐purity hypHSC preparation for transcriptomic analysis.
Marion Heckmann +9 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 8, 28 April 2026.Inhibition of DNA damage repair is a common mechanism to induce cancer cell death and, therefore, to treat cancers such as breast, prostate and ovarian cancer. This approach, although very attractive, has not been feasible for treating brain tumours due to the stringent structural features necessary for pharmaceutical agents to cross the blood–brain ...
Carina Dumo +8 more
wiley +1 more source
ChemSusChem, Volume 19, Issue 8, 28 April 2026.Heterogeneous catalysis has historically been developed in the gas phase, however, we have found it pertinent to highlight solvent effects that must be accounted for in liquid environments. Condensed phase catalysis, like that in biomass, petroleum and the conversion of CO2, stands to benefit from the typically overlooked discussion regarding the ...
Jim B. Floyd +3 more
wiley +1 more source
A Bifunctional Small Molecule Degrader of the Long Noncoding RNA MALAT1 Triplex
Chemistry – A European Journal, Volume 32, Issue 15, 22 April 2026.Targeting disease‐linked RNAs with small molecules is often limited by the modest impact of binding RNA structure alone. Here, we present a first‐in‐class bifunctional molecule that degrades the oncogenic lncRNA MALAT‐1 by inducing proximity between the RNA and a cleaving warhead.
Christian A. T. Brega +12 more
wiley +1 more source
Enzyme‐Assisted Synthesis and In Vitro Characterization of Bifunctional PCSK9 Inhibitors
ChemBioChem, Volume 27, Issue 7, 14 April 2026.Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an important therapeutic target for lowering cholesterol. Here, we report the assembly of a bifunctional molecule combining a PCSK9‐binding peptide with an asialoglycoprotein receptor (ASGPR) ligand.
Yuhui Zhang +8 more
wiley +1 more source