Results 151 to 160 of about 45,771 (255)

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, Volume 121, Issue 6, Page 1530-1540, June 2026.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source

Histopathological Assessment of Precision‐Cut Kidney Slices: A Live Human Tissue‐Based Model of Renal Fibrosis

APMIS, Volume 134, Issue 6, June 2026.
ABSTRACT Chronic kidney disease (CKD) is characterized by a progressive decline of renal function. A major challenge in CKD drug development is the low success rate of drug candidates, with fewer than 10% of drugs entering Phase I clinical trials demonstrating clinical benefit.
Andreas Riishede, Camilla Merrild, Seulgi Hyun, Mia G. Madsen, Anna K. Keller, Henricus A. M. Mutsaers, Rikke Nørregaard, Lene N. Nejsum   +7 more
wiley   +1 more source

Piperazine

, 2004
Piperazyna jest ciałem stałym, krystalicznym, występującym w postaci wolnej zasady lub różnych soli z kwasami nieorganicznymi i organicznymi. Stosowana jest w medycynie i weterynarii jako lek przeciwrobaczy oraz w przemyśle jako inhibitor korozji ...
Starek, A.
core  

Development of green purification process for piperazine-type drugs: a case study of quetiapine process development. [PDF]

RSC Adv
Huang W, Wang Y, Liu H, Li H, Yin Q.
europepmc   +1 more source

Mobile Carrier Structure for Facilitated CO2 Transport in Mixed Ionic Liquid Membrane Composed of 1‐Ethyl‐3‐Methylimidazolium Acetate and Diamine‐Functionalized Ionic Liquids

ChemSusChem, Volume 19, Issue 10, 27 May 2026.
Mixed ionic liquid membranes combining 1 ethyl‐3‐methylimidazolium acetate with diamine‐functionalized ionic liquids enable facilitated CO2 transport for membrane based direct air capture. Tuning diamine terminal groups and spacer length establishes an optimal range in CO2 solubility that enhances CO2 permeability, and one hydroxyethyl terminal group ...
Yu Nagai Kanasaki, Yuki Kohno, Takashi Makino   +2 more
wiley   +1 more source

Novel piperazine-triazole hybrids as PTP1B and alpha-amylase inhibitors: synthesis, biological evaluation and computational validation through network pharmacology, molecular docking, MD simulations, DFT and MMPBSA analysis. [PDF]

RSC Adv
Haroon M, Kamal S, Mansha A, Zahoor AF.
europepmc   +1 more source

Bioassay of piperazine and some plant products with earthworms.

, 1960
A bioassay method for estimating piperazine citrate and other vermicidal agents has been reported. Application of the bioassay method, based on the response of earthworms (Pheretima sp,) to the drugs in Ringer.Locke medium for rapid screening of ...
Krishnakumari, M. K., Majumder, S. K.
core  

Aminal-Linked Porous Piperazine Covalent Organic Polymers for Gold Sequestration from E-Waste with Exceptional Performance Metrics. [PDF]

ACS Appl Mater Interfaces
Kumar S, Bashri M, Aldaqqa NM, Gaber S, Belec B, Addicoat MA, Shetty D.   +6 more
europepmc   +1 more source

Molecular Editing of Bilobalide: Regioselective C-Ring Lactam Formation. [PDF]

Org Lett
Wang W, Scheeff S, Hau SC, Qin Y, Sillapachaiyaporn C, Ng BW.   +5 more
europepmc   +1 more source

Discovery of unprecedented prenylated indole piperazines and pyrazines through cryptic biosynthetic gene cluster heterologous expression. [PDF]

Nat Prod Bioprospect
Zha Z, He D, Song J, Guan Z, Han J, Liu C, Wang X, Zhu Y, Zhu H, Ye W, Li Q, Zhang Y, Zhou Y.   +12 more
europepmc   +1 more source