Results 131 to 140 of about 37,749 (227)

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

open access: yesAngewandte Chemie, Volume 138, Issue 31, 27 July 2026.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner   +2 more
wiley   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner   +2 more
wiley   +1 more source

Piperazine-Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice. [PDF]

open access: yesAdv Sci (Weinh)
Cao Y   +14 more
europepmc   +1 more source

Molecular mechanism of transition-state inhibitors of bacterial antibiotic efflux pumps. [PDF]

open access: yesNPJ Antimicrob Resist
Börnsen C   +12 more
europepmc   +1 more source

Synthesis and structural elucidation of a novel bis-spirooxindole from isatin and ethylenediamine. [PDF]

open access: yesBeilstein J Org Chem
Moreno-Gutiérrez I   +7 more
europepmc   +1 more source

Harnessing Random Polymers as Chemoselective Catalysts With Structural Adaptability: Epoxidation of Olefinic Quaternary Ammonium Salts via Charge Recognition

open access: yesChemistry – A European Journal, Volume 32, Issue 27, 17 July 2026.
The development of chemoselective catalysts that operate across structurally diverse substrates remains a long‐standing challenge. Here, we demonstrate that a random heteropolymer bearing carboxylic acid and urea residues functions as a general epoxidation catalyst for olefinic quaternary ammonium salts.
Yusei Fujii   +2 more
wiley   +1 more source

Design and Synthesis of Novel Purine Analogues as Potential IL-1β Inhibitors Targeting Vascular Inflammation. [PDF]

open access: yesChem Biodivers
Pournara DT   +6 more
europepmc   +1 more source

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