Piperazine-grafted magnetic graphene oxide as a sustainable heterogeneous catalyst for solvent-free Biginelli reaction. [PDF]
Rezaei-Seresht E +4 more
europepmc +1 more source
Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner +2 more
wiley +1 more source
Eco-friendly synthesis of an antimicrobial polymer (1,4-bis(methacryloyl)piperazine) via maghnite catalysis: <i>in vitro</i> activity and <i>in silico</i> drug-likeness. [PDF]
Derkaoui S +7 more
europepmc +1 more source
Late‐Stage Functionalization of Peptides on the Solid Phase
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
Piperazine-Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice. [PDF]
Cao Y +14 more
europepmc +1 more source
Molecular mechanism of transition-state inhibitors of bacterial antibiotic efflux pumps. [PDF]
Börnsen C +12 more
europepmc +1 more source
Synthesis and structural elucidation of a novel bis-spirooxindole from isatin and ethylenediamine. [PDF]
Moreno-Gutiérrez I +7 more
europepmc +1 more source
The development of chemoselective catalysts that operate across structurally diverse substrates remains a long‐standing challenge. Here, we demonstrate that a random heteropolymer bearing carboxylic acid and urea residues functions as a general epoxidation catalyst for olefinic quaternary ammonium salts.
Yusei Fujii +2 more
wiley +1 more source
Design and Synthesis of Novel Purine Analogues as Potential IL-1β Inhibitors Targeting Vascular Inflammation. [PDF]
Pournara DT +6 more
europepmc +1 more source

