Results 131 to 140 of about 97,443 (299)

Sulfenamides as flame retardants [PDF]

, 2015
FIELD OF THE INVENTION The present invention is in the field of flame retardants and relates to use of sulfenamides as flame retardants, in particular in polymeric sub ...
Aubert, Melanie, Pawelec, Weronika, Tirri, Teija, Wilen, Carl-Eric   +3 more
core  

The R203W substitution drives PACS‐1 syndrome by disrupting intramolecular regulation

The FEBS Journal, EarlyView.
The middle region (MR) of PACS‐1 controls engagement with specific partner proteins. This manuscript presents the structure of the Furin binding region (FBR) and how interactions with partners are regulated through the interplay between a basic patch in the FBR and an acidic cluster in the MR.
Troy C. Krzysiak, In‐Ja L. Byeon, Ryan Ponticelli, Mary E. Lucas, Lariah Thompson, Christopher DeHaven, Gary Thomas, Angela M. Gronenborn   +7 more
wiley   +1 more source

Probing skin photoallergens in reconstructed human epidermis: An EPR spin trapping investigation

Photochemistry and Photobiology, Volume 101, Issue 2, Page 275-281, March/April 2025.
We present an original proof‐of‐concept methodology to probe radical generation from allergens in contact with photoexposed skin, using electron paramagnetic resonance and spin trapping in a reconstructed human epidermis model mimicking real‐life exposure scenarios.
Yannick Port‐Lougarre, Guillaume Voegeli, Bertrand Vileno, Elena Giménez‐Arnau   +3 more
wiley   +1 more source

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Synthesis and Anti-Inflammatory Activity of (Z)-4-(2-(3-Oxopiperazin-2-ylidene)acetyl)benzoic Acid

Molbank
Non-steroidal anti-inflammatory drugs (NSAIDs) are an important class of medications; however, they have some drawbacks. We are developing a new NSAID with pronounced anti-inflammatory and analgesic activities and a very low toxicity—(Z)-3-(2-oxo-2-(p ...
Maksim V. Dmitriev, Ekaterina E. Khramtsova, Danila Y. Apuskin, Alexander I. Andreev, Ilya I. Kovalenko, Irina V. Mashevskaya, Andrey N. Maslivets   +6 more
doaj   +1 more source

Direct Mechanoorganocatalysis via Surface Functionalization of Milling Reactors With Amine Functions

ChemistryEurope, Volume 4, Issue 5, May 2026.
Surface functionalization of milling jars in epoxy resin furnished reactive milling jars, able to perform direct mechanoorganocatalysis with high efficiency, recyclability, and simplified purification. This proof of concept was applied successfully to base‐catalyzed Knoevenagel condensation and multicomponent reactions.
Joao Tanepau, Maxime Provost, Marie Gressier, Marie‐Joëlle Menu, Sandrine Duluard, Frédéric Lamaty, Julien Pinaud, Xavier Bantreil   +7 more
wiley   +1 more source

Design, Synthesis, Biological Evaluation, and Molecular Modeling Studies of Novel 2‐Aminothiazole Derivatives as Potential FOXM1 Inhibitors for Triple‐Negative Breast Cancer Therapy and Structure‐Activity Relationship

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Triple Negative Breast Cancer (TNBC) is one of the most aggressive subtypes of breast cancer (BC), which is associated with a very poor prognosis. It is a broad category of tumors with a variety of biological, clinical, and morphological characteristics.
Khaled A. N. Abusharkh, Venhar Çınar, Alper Onder, Merve Sıkık, Mustafa Guzel, Zuhal Hamurcu, Bulent Ozpolat, Mehmet Ay, Ferah Comert Onder   +8 more
wiley   +1 more source

A new crystalline daidzein-piperazine salt with enhanced solubility, permeability, and bioavailability

Frontiers in Pharmacology
To overcome the poor solubility, permeability, and bioavailability of the plant isoflavone daidzein (DAI), a novel salt of DAI with anhydrous piperazine (PIP) was obtained based on cocrystallization strategy.
Jiacheng Meng, Chenxu Qiu, Chenyue Lu, Xin He, Xinghua Zhao   +4 more
doaj   +1 more source

Identification and Characterization of Compounds with Inhibitory Properties towards Salmonella enterica Biofilms [PDF]

, 2016
First Place, Denman Undergraduate Research ForumSalmonella enterica serovar Typhi (S. Typhi), the causative agent of Typhoid Fever in humans, persists in the gallbladder of 3-5% of hosts after resolution of acute infection. In this chronic carrier state,
Moshiri, Jasmine
core  

ChemBang: Expanding the Chemical Space Around Small Molecules

Molecular Informatics, Volume 45, Issue 5, May 2026.
Schematic diagram of the underlying concepts behind ChemBang and the molecular generation process from a seed molecular structure by applying the three main categories of chemical transformations, namely, interchange of small substituents, replacement of ring systems, and scaffold enlargement by additional ring systems.
Diana Montes‐Grajales, Luca Menestrina, Ricard Garcia‐Serna, Jordi Mestres   +3 more
wiley   +1 more source