Results 111 to 120 of about 45,771 (255)
Tetraphenyl piperazine-1,4-diyldiphosphonate
, 2010 The molecule of the title compound, C28H28N2O6P2, is organized around an inversion center located at the centre of the piperazine ring. Both piperazine N atoms are substituted by P(O)(OC6H5)2 phosphoester groups.
Poorya Zargaran, Mehrdad Pourayoubi
core +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
The continuing significance of chiral agrochemicals
Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
PharmaceuticalsBackground/Objectives: Cancer is among the leading causes of mortality worldwide. In 2022 alone, the global cancer death toll stood at 9.74 million. Projections indicate that this figure will rise to 10.4 million by 2025.
Okan Güven +5 more
doaj +1 more source
Recent Advances in Piperazine Synthesis
, 2017 Piperazine ranks as the third most common N-heterocycle appearing in small-molecule pharmaceuticals. This review highlights recent advances in methods development for the construction of the piperazine ring system with particular emphasis on preparing ...
Mingji Dai, Kristen Gettys, Zhishi Ye
core +1 more source
Responsive Materials, EarlyView.This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun +8 more
wiley +1 more source
Formation and decomposition of 1-nitrosopiperazine in the CO2 capture process
, 2013 textPiperazine (PZ) is a cyclic diamine, which means it can absorb two moles of CO2 per mole of amine and potentially has a higher capacity for CO2 capture than monoethanolamine, the current solvent of choice for flue gas treatment.
Ashouripashaki, Mandana
core
Unusual backfolded binding poses of BAZ2A bromodomain binders
Acta Crystallographica Section D, EarlyView.We identified BAZ2A‐binding compounds assuming a peculiar, almost enclosed, conformation. These molecules pose a basis for the development of potent BAZ2A macrocyclic inhibitors, as performed for other bromodomains.BAZ2A is a large multidomain protein overexpressed in aggressive prostate cancer, where it potentiates migration and invasion of other ...
Andrea Dalle Vedove +5 more
wiley +1 more source
Chloroalkyl piperazine and nitrogen mustard porphyrins: Synthesis and anticancer activity
, 2004 Fifteen new chloroalkyl piperazine and nitrogen mustard porphyrins have been synthesized by the direct condensation of chloroalkyl piperazine, nitrogen mustard benzaldehyde, and pyrrole. Each porphyrin bears 1-4 chloroalkyl piperazine or nitrogen mustard
Guo, Can Cheng +2 more
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source