Results 41 to 50 of about 9,140 (175)

Can trigeminal sensations impact saltiness perception? A mini‐review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan   +2 more
wiley   +1 more source

Piperine attenuates cardiovascular, liver and metabolic changes in high carbohydrate, high fat-fed rats

open access: yes, 2011
Black pepper is used worldwide to enhance food flavor. We investigated dietary supplementation with piperine, the active principle of black pepper, to high carbohydrate, high fat (HCHF) diet-fed rats as a model of human metabolic syndrome.
Vishal Diwan   +5 more
core   +1 more source

Approaches for potentiating the effects of piperine [PDF]

open access: yes, 2021
Piperine is an alkaloid found in several species of Piperaceae family that are traditionally used as spices all around the world. Its nutraceutical properties have been investigated in recent years and this compound has attracted scientific attention, as
Smilkov, Katarina   +1 more
core  

Piperine Provides Neuroprotection against Kainic Acid-Induced Neurotoxicity via Maintaining NGF Signalling Pathway

open access: yesMolecules, 2022
The neuroprotective properties of piperine, the major alkaloid extracted from black pepper, have been under investigation, but its mechanism of action in excitotoxicity is still poorly understood.
Ting-Yang Hsieh, Yi Chang, Su-Jane Wang
doaj   +1 more source

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim   +5 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Piperine Ameliorates Trimellitic Anhydride-Induced Atopic Dermatitis-Like Symptoms by Suppressing Th2-Mediated Immune Responses via Inhibition of STAT6 Phosphorylation

open access: yesMolecules, 2020
Atopic dermatitis (AD) is a common inflammatory skin disease predominately related to Type 2 helper T (Th2) immune responses. In this study, we investigated whether piperine is able to improve AD symptoms using a trimellitic anhydride (TMA)-induced AD ...
Dae Woon Choi   +3 more
doaj   +1 more source

An update on Nanoparticle Formulation Design of Piperine to Improve its Oral bioavailability: A Review

open access: yesIraqi Journal of Pharmaceutical Sciences, 2023
Piperine, a crystalline alkaloid compound isolated from Piper nigrum, piper longum, and other types of piper, has had many fabulous pharmacological advantages for preventing and treating some specific diseases, such as analgesic, anti-inflammatory ...
Akhmad Kharis Nugroho   +3 more
doaj   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

open access: yesBritish Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Piperine biosynthesis in black pepper (Piper nigrum L.) [PDF]

open access: yes, 2021
Die Biosynthese des Piperins (1-Piperolpiperidin), ein Alkaloid essentiell für die charakteristische Schärfe des Pfeffers (Piper nigrum), war über Jahrzehnte ungeklärt. In dieser Arbeit wurden wichtige Enzyme der Biosynthese mittels RNA-Sequenzierung und
Schnabel, Arianne
core   +1 more source

Home - About - Disclaimer - Privacy