Results 151 to 160 of about 5,284 (226)

Comprehensive analysis of gut microbiota and fecal metabolites in patients with autism spectrum disorder. [PDF]

Front Microbiol
Zheng R, Huang S, Feng P, Liu S, Jiang M, Li H, Zheng P, Mi Y, Li E.   +8 more
europepmc   +1 more source

Development of a cell adhesion-based prognostic model for multiple myeloma: Insights into chemotherapy response and potential reversal of adhesion effects. [PDF]

Oncol Res
Hu Q, Wang M, Wang J, Tao Y, Niu T.
europepmc   +1 more source

Rhabdomyolysis during adjunctive treatment with cariprazine in a clozapine-resistant schizophrenia patient. [PDF]

Int Clin Psychopharmacol
Lommer K, Tutzer F, Hofer A.
europepmc   +1 more source

Cholinergic Control of GnRH Neuron Physiology and Luteinizing Hormone Secretion in Male Mice: Involvement of ACh/GABA Cotransmission. [PDF]

J Neurosci
Vastagh C, Farkas I, Csillag V, Watanabe M, Kalló I, Liposits Z.   +5 more
europepmc   +1 more source

FOXP2-immunoreactive corticothalamic neurons in neocortical layers 6a and 6b are tightly regulated by neuromodulatory systems. [PDF]

iScience
Qi G, Yang D, Messore F, Bast A, Yáñez F, Oberlaender M, Feldmeyer D.   +6 more
europepmc   +1 more source

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Reduction Of Clozapine-Induced Hypersalivation By Pirenzepine Is Safe

Pharmacopsychiatry, 2004
Hypersalivation is known as a frequent, disturbing, and socially stigmatizing side effect of therapy with the atypical antipsychotic clozapine. It has been shown that the addition of the anticholinergic pirenzepine is able to reduce clozapine-induced hypersalivation, probably by blocking M4-receptors. Nevertheless, a pharmacokinetic interaction between
Bernhard Weber, Jürgen Fritze, C Hiemke, B. Schneider, H Weigmann   +4 more
openaire   +4 more sources

Pirenzepine distinguishes between different subclasses of muscarinic receptors

Nature, 1980
Some antagonists exhibit tissue selectivity in their pharmacological antagonism of muscarinic responses. However, the affinity constants for equilibrium binding of classical antagonists to muscarinic receptors in subcellular preparations have shown only small variations in different peripheral tissues and regions of the brain. The binding curves do not
Nigel J. M. Birdsall, Arnold S. V. Burgen, Edward C. Hulme, Hammer R, Christopher P. Berrie   +4 more
openaire   +4 more sources

Blockade of spatial learning by the M1 muscarinic antagonist pirenzepine

Psychopharmacology, 1987
Two experiments were conducted to determine the effects of the M1 muscarinic receptor antagonist pirenzepine on place navigation in a water maze. In the first experiment rats were required to learn the location of a hidden platform following intracerebroventricular injections of equimolar doses of pirenzepine or scopolamine methylbromide.
Chris L.E. Broekkamp, J. H. M. Jansen, Jim J. Hagan   +2 more
openaire   +4 more sources

Pirenzepine Blunts the Pulmonary Parenchymal Response to Inhaled Methacholine

Pulmonary Pharmacology, 1995
To determine the role of M1 muscarinic receptors in the response of the pulmonary parenchyma to inhaled methacholine (MCh), 20 mongrel, out-bred puppies, 8-10 weeks of age were challenged following pretreatment with either saline (control), UH-AH37 (a combined M1 & M3 receptor blocker), or pirenzepine (a relatively selective M1 receptor blocker).
Sly, Peter D., Willet, Karen E., Kano, Sohei, Lanteri, Celia J., Wale, Janet   +4 more
openaire   +5 more sources

Modulation of gallbladder contraction by pirenzepine in man

Pharmacological Research, 1995
The mechanism(s) by which cholinergic innervation modulates gallbladder contraction are not fully understood. To elucidate the role of muscarinic M1 receptors in the mediation of gallbladder contraction, we investigated gallbladder volume reduction, plasma cholecystokinin (CCK), and pancreatic polypeptide (PP) responses in humans during cephalic and ...
W.Y. Chey, Filiz Onat, E Tankurt, N Gurmen, N.B. Ulusoy, B. Yegˇen, T Biren, Şule Oktay   +7 more
openaire   +3 more sources