Results 161 to 170 of about 4,218 (200)
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Modulation of gallbladder contraction by pirenzepine in man
Pharmacological Research, 1995The mechanism(s) by which cholinergic innervation modulates gallbladder contraction are not fully understood. To elucidate the role of muscarinic M1 receptors in the mediation of gallbladder contraction, we investigated gallbladder volume reduction, plasma cholecystokinin (CCK), and pancreatic polypeptide (PP) responses in humans during cephalic and ...
B, Yeğen +7 more
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Psychometric studies of pirenzepine.
Scandinavian journal of gastroenterology. Supplement, 1981A single dose of 10 mg of pirenzepine given i.m. to 7 healthy volunteers did not elicit local or general signs of intolerance within 6 hours after injection. We also found no significant differences in tests of vegetative symptomatology, visual motor coordination, attention concentration, critical flicker test threshold, nor any other aspects of the ...
E, Kuhn, R, Honzák
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Central action of pirenzepine.
Polish journal of pharmacology and pharmacy, 1982Pirenzepine, (5,11-dihydro-11-[(4-methylpiperazin-1-yl)-acetyl]-6H-pyrido-[2,3] [1,4]-benzodiazepin-6-one dihydrochloride), tested on rats and mice, did not demonstrate any conspicuous behavioral action: it did not counteract reserpine hypothermia in mice, the L-DOPA hypermotility of mice, and (with the exception of very large doses) the amphetamine ...
Z, Rogóz, G, Skuza, H, Sowińska
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[The bronchodilating effect of pirenzepine].
Arerugi = [Allergy], 1992The purpose of this study was to clarify the bronchodilating effect of pirenzepine (PZ) and to verify its mechanism. Ten asthmatic patients (6 men, 4 women: aged 20 to 65, 5 atopic 5 non-atopic) and ten non-asthmatic volunteers (8 men, 2 women: aged 25 to 60) were studied. Forced vital capacity (FVC), forced expiratory volume in one second (FEV1.0) and
T, Shioya +5 more
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The pharmacokinetic profile of pirenzepine.
Scandinavian journal of gastroenterology. Supplement, 1980This paper gives a brief review of the pharmacokinetic studies performed on pirenzepine (L S 519 Cl2, Gastrozepin hitherto. Particular attention will be paid thereby to the clinical significance of the pharmacokinetic parameters.
R, Hammer, F W, Koss
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Pirenzepine for clozapine-induced hypersalivation
The Lancet, 1995J, Fritze, T, Elliger
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[Intravenous pirenzepine reduces salivary secretion rapidly].
Masui. The Japanese journal of anesthesiology, 1994We evaluated the effects of pirenzepine on salivary secretion and heart rate, comparing them with those after atropine. Forty-two patients for gynecological operations were divided into three groups. P, A and C groups received pirenzepine 10 mg, atropine 0.5 mg and saline 1 ml intravenously 4 min before induction. Salivary secretion was aspirated at 30,
M, Taneda +6 more
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Pirenzepine in Erosive Duodenitis
Scandinavian Journal of Gastroenterology, 1985M. Guslandi +4 more
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