Results 21 to 30 of about 12,593 (182)

Cholesterol Significantly Affects the Interactions between Pirfenidone and DPPC Liposomes: Spectroscopic Studies

open access: yesBiophysica, 2022
In this work, we studied the effect of as on the interaction of membrane DPPC with the key antifibrotic drug pirfenidone. Liposomal forms of pirfenidone were obtained using passive loading.
Irina M. Le-Deygen   +4 more
doaj   +1 more source

Role of pirfenidone in the management of pulmonary fibrosis [PDF]

open access: yes, 2017
Keith C Meyer,1,2 Catherine A Decker3,4 1University of Wisconsin Lung Transplant and Advanced Lung Disease Program, 2Department of Medicine, Section of Allergy, Pulmonary and Critical Care Medicine, Clinical Sciences Center, University of Wisconsin ...
Catherine Decker   +3 more
core   +1 more source

Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models

open access: yesJCI Insight, 2022
Despite decades of research, there is no specific therapy for acute pancreatitis (AP). In the current study, we have evaluated the efficacy of pirfenidone, an antiinflammatory and antifibrotic agent that is approved by the FDA for treatment of idiopathic
Ejas Palathingal Bava   +17 more
doaj   +1 more source

Nintedanib, Pirfenidone and the combination

open access: yes, 2022
Pairwise meta-analysis on nintedanib, pirfenidone and the combination of the ...
Tyler Pitre
core   +1 more source

Inhibition of Ureteral Stricture by Pirfenidone-Loaded Nanoparticle-Coated Ureteral Stents with Slow-Release Pirfenidone

open access: yesInternational Journal of Nanomedicine, 2022
Zhaosheng Jiang,1,* Jiahao Wang,2,* Wei Meng,1,* Youlang Zhou,3 Limin Ma,1 Yangbo Guan1 1Department of Urology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, People’s Republic of China; 2Department ...
Jiang Z   +5 more
doaj  

Disseminated varicella-zoster virus infection with abdominal pain possibly caused by pirfenidone: A case report

open access: yesRespiratory Medicine Case Reports, 2018
We report a case of chronic hypersensitivity pneumonitis treated with pirfenidone in a 76-year-old woman who complained of acute-onset abdominal pain and rashes.
Akihiro Shiroshita   +2 more
doaj   +1 more source

Pirfenidone: an update on clinical trial data and insights from everyday practice [PDF]

open access: yesEuropean Respiratory Review, 2014
Pirfenidone is an orally active, small molecule that inhibits synthesis of profibrotic and inflammatory mediators. It was approved for the treatment of adults with mild-to-moderate idiopathic pulmonary fibrosis in the European Union based on the results ...
Michael Kreuter
doaj   +1 more source

Tolerability to pirfenidone therapy.

open access: yes, 2020
Tolerability to pirfenidone therapy.
Zuojun Xu (129186)   +4 more
core   +1 more source

Anti-fibrotic effects of pirfenidone and rapamycin in primary IPF fibroblasts and human alveolar epithelial cells

open access: yesBMC Pulmonary Medicine, 2018
Background Pirfenidone, a pleiotropic anti-fibrotic treatment, has been shown to slow down disease progression of idiopathic pulmonary fibrosis (IPF), a fatal and devastating lung disease.
M. Molina-Molina   +8 more
doaj   +1 more source

Comparison of cause of pirfenidone discontinuation between patients who were treated with full recommended dose of pirfenidone (1800mg/d) and relatively low dose of pirfenidone (600mg/d or 1200mg/d).

open access: yes, 2021
Comparison of cause of pirfenidone discontinuation between patients who were treated with full recommended dose of pirfenidone (1800mg/d) and relatively low dose of pirfenidone (600mg/d or 1200mg/d).
Soon Seog Kwon (11873790)   +8 more
core   +1 more source

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