Results 31 to 40 of about 372,669 (197)

Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors [PDF]

open access: yes, 2005
Genetic perturbations of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are widely used to dissect molecular mechanisms of sensory coding, learning, and memory.
Shimshek Derya R   +39 more
core   +1 more source

On the ictogenic properties of the piriform cortex in vitro [PDF]

open access: yesEpilepsia, 2012
SummaryPurpose: The piriform cortex (PC) is known to be epileptic‐prone and it may be involved in the manifestation of limbic seizures. Herein, we have characterized some electrophysiologic and pharmacologic properties of the spontaneous epileptiform activity generated by PC networks maintained in vitro.Methods: We performed field potential recordings ...
Panuccio G   +5 more
openaire   +2 more sources

Connectivity, plasticity, and function of neuronal circuits in the zebrafish olfactory forebrain [PDF]

open access: yes, 2014
For most living animals such as worms, insects, fishes, rodents and humans, chemical cues from the environment (odorants) play critical roles in guiding behaviors important for survival, including preying, mating, breeding, and escaping.
Zou, Ming
core   +1 more source

Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex

open access: yeseLife, 2017
Olfactory perception and behaviors critically depend on the ability to identify an odor across a wide range of concentrations. Here, we use calcium imaging to determine how odor identity is encoded in olfactory cortex.
Benjamin Roland   +4 more
doaj   +1 more source

Assessment of olfactory information in the human brain using 7-Tesla functional magnetic resonance imaging

open access: yesNeuroImage, 2021
Olfaction could prove to be an early marker of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. To use olfaction for disease diagnosis, elucidating the standard olfactory functions in healthy humans is necessary.
Yuka Donoshita   +3 more
doaj   +1 more source

Neuromodulation and the Functional Dynamics of Piriform Cortex [PDF]

open access: yesChemical Senses, 2001
Acetylcholine and norepinephrine have a number of effects at the cellular level in the piriform cortex. Acetylcholine causes a depolarization of the membrane potential of pyramidal cells and interneurons, and suppresses the action potential frequency accommodation of pyramidal cells.
C, Linster, M E, Hasselmo
openaire   +2 more sources

Functional imaging of the piriform cortex in focal epilepsy [PDF]

open access: yesExperimental Neurology, 2020
Experiments in animal models have identified specific brain regions such as the deep anterior piriform cortex as important for controlling the initiation or propagation of both generalized and focal seizure activity. However, there is little experimental evidence to translate these observations to the control of focal seizures in humans.
Koepp, Matthias, Galovic, Marian
openaire   +4 more sources

Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: Contribution of delayed neuronal cell death to seizure-induced neuronal injury

open access: yesNeurobiology of Disease, 2005
Pilocarpine-induced status epilepticus (PCSE) is a widely used model to study neurodegeneration in limbic structures after prolonged epileptic seizures.
Jens Weise   +5 more
doaj   +1 more source

Individual odor hedonic perception is coded in temporal joint network activity

open access: yesNeuroImage, 2021
Intro: The human sense of smell is highly individual and characterized by a strong variability in the perception and evaluation of olfactory stimuli, depending on cultural imprint and current physiological conditions.
Paul Ruser   +4 more
doaj   +1 more source

Recurrent circuitry is required to stabilize piriform cortex odor representations across brain states

open access: yeseLife, 2020
Pattern completion, or the ability to retrieve stable neural activity patterns from noisy or partial cues, is a fundamental feature of memory. Theoretical studies indicate that recurrently connected auto-associative or discrete attractor networks can ...
Kevin A Bolding   +4 more
doaj   +1 more source

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