Results 81 to 90 of about 357,031 (196)

Spared piriform cortical single-unit odor processing and odor discrimination in the Tg2576 mouse model of Alzheimer's disease. [PDF]

PLoS ONE, 2014
Alzheimer's disease is a neurodegenerative disorder that is the most common cause of dementia in the elderly today. One of the earliest reported signs of Alzheimer's disease is olfactory dysfunction, which may manifest in a variety of ways.
Wenjin Xu, Mirielle Lopez-Guzman, Chelsea Schoen, Shane Fitzgerald, Stephanie L Lauer, Ralph A Nixon, Efrat Levy, Donald A Wilson   +7 more
doaj   +1 more source

Words and Scents: How Language Shapes and Skews Olfactory Processing

Topics in Cognitive Science, EarlyView.
Abstract Research on language and olfaction presents a paradox. Language appears to support the formation of odor categories, yet it can also hinder odor recognition through verbal interference, highlighting that different olfactory processes get affected in distinct ways.
Norbert Vanek
wiley   +1 more source

The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity

Communications Biology, 2023
Loss of the clock gene, Bmal1, in the piriform cortex largely abolishes the circadian rhythm of odor-evoked activity in mice, suggesting a broader regulatory role for Bmal1 in olfactory neural activity and transmission.
Shunsuke Takeuchi, Kimiko Shimizu, Yoshitaka Fukada, Kazuo Emoto   +3 more
doaj   +1 more source

Quantifying the Diamagnetic and Paramagnetic Components of Beta‐Amyloid Plaques Using Decomposed Quantitative Susceptibility Mapping in Mouse Models of Alzheimer's Disease

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Ex vivo MRI was performed on AD mouse models using high‐resolution multi‐echo gradient‐echo imaging on a 9.4T scanner to generate quantitative susceptibility maps (QSM) and separate diamagnetic and paramagnetic components. Amyloid‐β$$ \beta $$ plaques were detected from the susceptibility maps.
Juan Liu, Jingjia Chen, Season K. Wyatt‐Johnson, Jie Chen, Zhuoheng Liu, Hongbo Wu, Li Feng, Randy R. Brutkiewicz, Nian Wang   +8 more
wiley   +1 more source

Response: New neurons from old beliefs in the adult piriform cortex? A Commentary on: “Occurrence of new neurons in the piriform cortex” [PDF]

Frontiers in Neuroanatomy, 2015
In the commentary by Nacher and Bonfanti (2015) on our recent paper in Frontiers of Neuroanatomy (Yuan et al., 2015), they argued that subpopulations of layer II cells in mammalian paleocortex, including the piriform cortex (PC), are embryonic origin-immature neurons expressing “plastic” neuronal markers, and only a limited number of PC neurons are ...
Yuan, TF, So, KF, Liang, Y
openaire   +4 more sources

Prenatal genesis of layer II doublecortin expressing neurons in neonatal and young adult guinea pig cerebral cortex

Frontiers in Neuroanatomy, 2015
Cells expressing doublecortin (DCX+) occur at cortical layer II, predominantly over the paleocortex in mice/rats, but also across the neocortex among larger mammals.
Yan eYang, Mi-Xin eXie, Jian-Ming eLi, Xia eHu, Peter ePatrylo, Xue-Gang eLuo, Yan eCai, ZHIYUAN eLI, Xiao-Xin eYan   +8 more
doaj   +1 more source

Virtual brain endocasts of the palaeanodont Metacheiromys marshi and the neurosensory evolution of early Pholidotamorpha

Journal of Anatomy, Volume 249, Issue 4, Page 821-846, October 2026.
We describe the endocranial anatomy of Metacheiromys marshi. Decrease in olfaction and eye movement control occurred through time in Pholidotamorpha and is likely linked to fossorial adaptations. The development of the orbital gyrus might be related to the evolution of myrmecophagy and the emergence of a protrusile tongue in early Pholidotamorpha ...
Eduard Cabasés Bru, Raquel Moya‐Costa, John R. Wible, Stephen L. Brusatte, Ornella C. Bertrand   +4 more
wiley   +1 more source

New neurons from old beliefs in the adult piriform cortex? A Commentary on: “Occurrence of new neurons in the piriform cortex” [PDF]

Frontiers in Neuroanatomy, 2015
In a recent mini-review (Yuan et al., 2015), support is given to the idea that neurons are generated during adulthood in the mammalian piriform cortex (PC), their periventricular origin being also discussed. It is known since long time that a subpopulation of cortical layer II cells in the adult PC of rodents express immature neuronal markers such as ...
Nacher, Juan, Bonfanti, Luca
openaire   +2 more sources

Olfactory tract transection enhances adult neurogenesis in piriform cortex

, 2009
Adult neurogenesis happens continuously in olfactory bulb. Loss of sensory input to the olfactory bulb leads to decreased formation of new neurons in the bulb.
Liang, Y, Ellis-Behnke, RG, Tay, DKC, So, KF, Yuan, T   +4 more
core   +1 more source

Parvalbumin interneurons in Alzheimer's disease: Physiological insights and pathophysiological mechanisms

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Physiological and Pathological Alterations in PV+ Neurons: Under physiological conditions, PV+ interneurons exhibit fast‐spiking properties and generate gamma oscillations at the cost of high energy consumption. In AD, PV+ neurons display abnormalities in ion channels, dendrites, neurotransmission, energy metabolism, and neural oscillations, ultimately
Mengyan Wu, Xingdong Zeng, Yongle Cai, Haonan Chen, Qianying Li, Hao Yang   +5 more
wiley   +1 more source