Results 81 to 90 of about 372,669 (197)

The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity

Communications Biology, 2023
Loss of the clock gene, Bmal1, in the piriform cortex largely abolishes the circadian rhythm of odor-evoked activity in mice, suggesting a broader regulatory role for Bmal1 in olfactory neural activity and transmission.
Shunsuke Takeuchi, Kimiko Shimizu, Yoshitaka Fukada, Kazuo Emoto   +3 more
doaj   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, Volume 13, Issue 61, 3 November 2026.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Unraveling the Relationship Between Nr4a2 and Fezf1 Expression in the Developing Feline Telencephalon Within the Genoarchitectonic Context of Claustral and Amygdalar Development

Journal of Comparative Neurology, Volume 534, Issue 11, November 2026.
To define the emergence of the claustral complex in relation to the expression patterns of Nr4a2 and Fezf1 in the domestic cat, a species with more protracted prenatal development than the mouse, we performed a genoarchitectonic analysis. Nr4a2 marked differentiating claustral neurons within the LPall mantle, whereas Fezf1 was broadly expressed in the ...
Nikistratos Siskos, Andreas‐Rafail Vasileiou, Evangelia Archontoulaki, Alexandra Tsakalidou‐Rafailidou, Charalampos Ververidis, George Skavdis, Maria E. Grigoriou   +6 more
wiley   +1 more source

Cell-Type-Specific Whole-Brain Direct Inputs to the Anterior and Posterior Piriform Cortex

Frontiers in Neural Circuits, 2020
The piriform cortex (PC) is a key brain area involved in both processing and coding of olfactory information. It is implicated in various brain disorders, such as epilepsy, Alzheimer’s disease, and autism.
Li Wang, Li Wang, Zhijian Zhang, Jiacheng Chen, Anne Manyande, Rafi Haddad, Qing Liu, Qing Liu, Fuqiang Xu, Fuqiang Xu, Fuqiang Xu, Fuqiang Xu, Fuqiang Xu   +12 more
doaj   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, Volume 13, Issue 59, 23 October 2026.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Odor quality coding and categorization in human posterior piriform cortex [PDF]

, 2009
Efficient recognition of odorous objects universally shapes animal behavior and is crucial for survival. To distinguish kin from nonkin, mate from nonmate and food from nonfood, organisms must be able to create meaningful perceptual representations of ...
Haynes, J., Howard, J., Gottfried, J., Plailly, Jane, John-Dylan Haynes, Gottfried, J A, Howard, J D, Plailly, J, James D Howard, Grüschow, M., Plailly, J., Marcus Grueschow, Howard, James, Haynes, J D, Grueschow, M, Jane Plailly, Grueschow, Marcus, Haynes, John-Dylan, Jay A Gottfried, Gottfried, Jay   +19 more
core   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

A topographical organization in the primary olfactory cortex

Nature Communications
A key principle of most sensory cortices is their topographic organization, in which neurons in proximity exhibit similar tuning properties, typically varying along a specific stimulus feature. However, such an organization has not yet been identified in
Shira Taragin, Or Bashan, Tal Dalal, Katya Belelovsky, Rafi Haddad   +4 more
doaj   +1 more source

Feasibility of Transoral Robotic Total Laryngectomy With the Da Vinci Single Port Robotic System

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
The study reports the successful use of the Da Vinci Single Port (SP) Robotic system for transoral robotic total laryngectomy. Surgical technique is described in detail. The procedure was followed by favorable postoperative recovery and no evidence of locoregional recurrence or delayed complications at 6 months.
Matthias De Witte, Jolente Boulanger, George Lawson, Catherine Dick, Frederick Dochy, Tom Vauterin   +5 more
wiley   +1 more source

Quantifying the Diamagnetic and Paramagnetic Components of Beta‐Amyloid Plaques Using Decomposed Quantitative Susceptibility Mapping in Mouse Models of Alzheimer's Disease

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Ex vivo MRI was performed on AD mouse models using high‐resolution multi‐echo gradient‐echo imaging on a 9.4T scanner to generate quantitative susceptibility maps (QSM) and separate diamagnetic and paramagnetic components. Amyloid‐β$$ \beta $$ plaques were detected from the susceptibility maps.
Juan Liu, Jingjia Chen, Season K. Wyatt‐Johnson, Jie Chen, Zhuoheng Liu, Hongbo Wu, Li Feng, Randy R. Brutkiewicz, Nian Wang   +8 more
wiley   +1 more source