Results 101 to 110 of about 112,170 (313)

Cancer Risk in Marfan Syndrome: A Swedish Population‐Based Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
The cancer risk in Marfan syndrome, an autosomal dominant connective tissue disorder, largely remains to be explored. In this population‐based matched cohort study of 1544 Swedish patients, the overall cancer risk in adults with Marfan syndrome showed no significant increase, except for the risk of endocrine tumours with a nearly threefold increase ...
Ida Nordgren   +8 more
wiley   +1 more source

The Effects of Cannabinoid Compounds on the Endocrine System

open access: yesQuality in Sport
Cannabinoids are chemical compounds that occur naturally in the cannabis plant. They have been known for thousands of years and have been used to treat conditions such as asthma, malaria, hypertension, and spasticity.
Julia Inglot   +9 more
doaj   +1 more source

Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells

open access: yesThe Scientific World Journal, 2014
Early and late endocrine disorders are among the most common complications in survivors after hematopoietic allogeneic- (allo-) and autologous- (auto-) stem cell transplant (HSCT).
Francesco Orio   +9 more
doaj   +1 more source

Sexual dimorphism in hormone–gut microbiome associations across reproductive states in wild giant pandas

open access: yesiMetaOmics, EarlyView.
Gut microbiota–host endocrine interactions in wild mammals remain poorly understood. Giant pandas experience seasonal dietary shifts and constrained annual reproduction, offering an ideal model to investigate microbiome–endocrine coupling. We integrated fecal hormone profiling, microsatellite‐based individual identification, and gut microbiome ...
Qinlong Dai   +10 more
wiley   +1 more source

Lipopolysaccharide Challenge Reveals Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Murine Systemic Lupus Erythematosus

open access: yesBrain Sciences, 2018
Crosstalk between the brain and innate immune system may be dysregulated in systemic lupus erythematosus (SLE), a chronic autoimmune disease that presents with dysautonomia and aberrant inflammation.
Grace S. Pham, Keisa W. Mathis
doaj   +1 more source

Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay

open access: yes, 1999
Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Meeks, JJ   +12 more
core  

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi   +13 more
wiley   +1 more source

Stress-induced obesity in mice causes cognitive decline associated with inhibition of hippocampal neurogenesis and dysfunctional gut microbiota

open access: yesFrontiers in Microbiology
Effects of stress on obesity have been thoroughly studied in high-fat diet fed mice, but not in normal diet fed mice, which is important to clarify because even on a normal diet, some individuals will become obese under stress conditions.
Yu-e Liu   +7 more
doaj   +1 more source

Plasma cortisol variations in dairy cows after some usual or unusual manipulations

open access: yesItalian Journal of Animal Science, 2010
The increase of blood cortisol is a common consequence of the acute stress; this has generally positive effects, despite not completely understood (Sapolsky et al. 2000).
M. Bionaz   +3 more
doaj   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

open access: yesInterdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi   +18 more
wiley   +1 more source

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