Hypersecretion of ACTH and PRL from pituitary adenoma in MEN1, adequately managed by medical therapy [PDF]
A 54-year-old man had gastrinoma, parathyroid hyperplasia and pituitary tumor. His family history indicated that he might have multiple endocrine neoplasia type 1 (MEN1). MEN1 gene analysis revealed a heterozygous germline mutation (Gly156Arg). Therefore,
Shinsuke Uraki +7 more
doaj +3 more sources
Descriptive Epidemiology and Survival Analysis of Prolactinomas and Cushing’s Disease in Korea [PDF]
Background Only a few studies have established the epidemiology of prolactinoma and Cushing’s disease in Korea. Furthermore, the incidence of these disease are increasing than before associated with the development of technologies.
Jin Sun Park +4 more
doaj +1 more source
Pancreatic ACTH Hypersecretion and Pituitary Macroadenoma
Abstract A 55-year-old woman admitted for hypertensive emergency and myocardial infarction reported weight gain, muscle weakness, easy bruising, and recent-onset diabetes in the past 3 to 12 months. Urinary and salivary cortisol and adrenocorticotropin hormone (ACTH) levels were elevated. Pituitary imaging detected a macroadenoma.
Chiara M Bettale +3 more
openaire +2 more sources
A human ACTH-secreting corticotroph tumoroid model
Background: Cushing disease (CD), although rare, is a life-threatening disorder caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma, which leads to excess adrenal-derived cortisol.
Dongyun Zhang +8 more
doaj +1 more source
An extremely rare case of calcinosis cutis in human Cushing’s disease
Cushing’s disease or pituitary adrenocorticotropic hormone (ACTH)-dependent Cushing’s syndrome is considered a rare condition. It is caused by hypersecretion of the ACTH by a pituitary adenoma that ultimately induces endogenous hypercortisolism by ...
Najoua Rbiai +3 more
doaj +1 more source
Long-term follow-up on Cushing disease patient after transsphenoidal surgery [PDF]
Cushing disease is caused by excessive adrenocorticotropic hormone (ACTH) production by the pituitary adenoma. Transsphenoidal surgery is its first-line treatment.
Insook Jeong +5 more
doaj +1 more source
Cushing’s syndrome due to ectopic adrenocorticotropic hormone (ACTH) secretion (EAS) by a pheochromocytoma is a challenging condition. A woman with hypertension and an anamnestic report of a ‘non-secreting’ left adrenal mass developed uncontrolled blood ...
Luca Foppiani +8 more
doaj +1 more source
The effect of sodium valproate in Cushing's disease, Nelson's syndrome and Addison's disease [PDF]
We investigated the effect of sodium valproate on plasma ACTH and serum cortisol concentrations in different pathological states of ACTH hypersecretion.
Allolio, B. +4 more
core +1 more source
A rare case of ectopic ACTH syndrome originating from malignant renal paraganglioma
SUMMARY Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of a non-pituitary ACTH-secreting tumor leading to Cushing’s syndrome.
Esra Tutal +7 more
doaj +1 more source
Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion [PDF]
We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis.
A Chatelain +19 more
core +1 more source

