Results 31 to 40 of about 2,508 (105)

Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release [PDF]

, 2007
We investigated the effect of the glucocorticoid receptor (GR) antagonist Org 34850 on fast and delayed inhibition of corticosterone secretion in response to the synthetic glucocorticoid methylprednisolone (MPL).
Craighead, Mark, Grassie, Morag, Harrison, Louse R., Lightman, Stafford L., MacSweeney, Cliona P., Spiga, Francesca, Thomson, Fiona .J., Wood, Susan A.   +7 more
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Cushing’s disease [PDF]

, 2012
Cushing’s disease, or pituitary ACTH dependent Cushing’s syndrome, is a rare disease responsible for increased morbidity and mortality. Signs and symptoms of hypercortisolism are usually non specific: obesity, signs of protein wasting, increased blood ...
Bernard Conte-Devolx, Frederic Castinetti, Isabelle Morange, Thierry Brue   +3 more
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Subclinical Cushing’s Disease with High-Molecular-Weight Forms of Adrenocorticotropic Hormone Production

Case Reports in Endocrinology
Production of the high-molecular-weight forms of adrenocorticotropic hormone (big-ACTH) has been reported in a small number of ectopic ACTH syndrome and ACTH-producing pituitary macroadenoma.
Takahiko Inukai, Nozomi Harai, Yukie Nakagawa, Tadatsugu Hosokawa, Airi Antoku, Yuko Muroi, Masakazu Ogiwara, Kyoichiro Tsuchiya   +7 more
doaj   +1 more source

Ga-DOTATOC PET/CT in the Localization of Pituitary Tumors in Cushing’s Disease [PDF]

Endocrinology and Metabolism
Background This study aimed to determine the value of 68Ga-DOTATOC positron emission tomography/computed tomography (PET/CT) in localizing adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas.
Kyungwon Kim, Dongwoo Kim, Min-Ho Lee, Yae Won Park, Sung Soo Ahn, Ju Hyung Moon, Eui Hyun Kim, Sun Ho Kim, Cheol Ryong Ku, Eun Jig Lee   +9 more
doaj   +1 more source

Pituitary adenomas, some diagnostic and therapeutical aspects [PDF]

, 1994
The treatment of almost all types of pituitary adenomas has changed considerably in recent years. New types of drugs as well as improved application forms of older drug therapies are now becoming more and more available for everyday treatment of patients
Herder, W.W. (Wouter) de, Lamberts, S.W.J. (Steven), Lely, A-J. (Aart-Jan) van der   +2 more
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Consensus on the diagnosis of Cushing’s disease: a collaborative statement from the Korean Endocrine Society and Japan Endocrine Society

Endocrine Journal
Cushing’s disease (CD) is a rare but serious endocrine disorder caused by excessive cortisol secretion due to adrenocorticotropic hormone–secreting pituitary tumors.
Jeongmin Lee, Hidenori Fukuoka, Seung Shin Park, A Ram Hong, Jung Hee Kim, Sang Ouk Chin, Han-Sang Baek, Dong-Jun Lim, Kazunori Kageyama, Mitsuru Nishiyama, Shigeyuki Tahara, Ken-Ichi Oyama, Akira Sugawara, Miho Yamashita, Naoko Inoshita, Hiroshi Arima, Byung-Joon Kim, Yoon-Sok Chung, Soon Jib Yoo, Michio Otsuki, Mi-kyung Kim, The Committee of Clinical Practice Guideline of Korean Endocrine Society, Korean Neuroendocrine Study Group of Korean Endocrine Society   +22 more
doaj   +1 more source

Improvement in cognitive impairment following the successful treatment of endogenous Cushing’s syndrome-a case report and literature review

BMC Endocrine Disorders, 2019
Background Endogenous Cushing’s syndrome, a rare endocrine disorder, characterised by chronic cortisol hypersecretion, results in neuropsychiatric disturbances and in cognitive deficits, which are only partially reversible after the biochemical remission
Malgorzata Monika Brzozowska, Sacha Kepreotis, Fiona Tsang, Sully Xiomara Fuentes- Patarroyo   +3 more
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A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism [PDF]

, 2016
Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease.
Araújo, Luiz Antônio de, Boguszewski, Cesar L., Bronstein, Marcello D., Gadelha, Mônica R., Miranda, Paulo Augusto Carvalho, Musolino, Nina Rosa Castro, Naves, Luciana Ansaneli, Oliveira Júnior, Antônio Ribeiro, Vieira Neto, Leonardo, Vilar, Lucio   +9 more
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TRH: Pathophysiologic and clinical implications [PDF]

, 1985
Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
A. Enjalbert, A. H. Barnett, A. H. Tashjian, A. I. Faden, A. J. L. Clark, A. Mongioi, B. M. Arafah, C. Carr, C. Faglia, C. M. Feek, C. R. Pickardt, C. R. Pickardt, C. R. Pickardt, C. R. Pickardt, C. R. Pickardt, C. R. Pickardt, D. Evain-Brion, D. S. Cooper, E. Flückiger, E. Hefco, E. Montoya, E. Roti, F. Guignier, F. Labrie, F. Massara, G. E. Shambaugh III, G. F. F. Pieters, G. Faglia, G. Faglia, G. Faglia, G. Faglia, G. Faglia, G. N. Burrow, G. P. Ceda, H. J. Chen, H. M. Fraser, J. B. Martin, J. F. Wilber, J. Habermann, J. J. Staub, J. Klindt, J. Köbberling, J. R. Sowers, J. R. Sowers, J. Sack, J.-N. Hugues, K. Hiramatsu, K. Horn, K. O. Nillson, K. W. Wenzel, K. Werder von, L. S. Jacobs, L. Wartofsky, L. Ø. Dolva, L. Ø. Dolva, L. Ø. Dolva, M. F. Scanlon, M. F. Scanlon, M. F. Scanlon, M. L'Hermite, M. M. Rabello, M. Otsuki, M. Szabo, O. Benkert, P. C. Scriba, P. C. Scriba, P. C. Scriba, P. J. Snyder, R. A. Maurer, R. Hall, R. M. Lechan, S. Ahuja, S. F. Kuku, S. Refetoff, S. Urman, St. M. Foord, T. K. Mallik, T. Mitsuma, V. B. Petersen, W. E. Cobb, W. K. Engel, W. Vale, Y. Koch   +82 more
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Medical treatment of Cushing's disease: Overview and recent findings

International Journal of General Medicine, 2009
Stephanie Smooke Praw1, Anthony P Heaney1,21Department of Medicine, 2Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USAAbstract: Cushing's disease, due to pituitary adrenocorticotropic hormone (ACTH ...
Stephanie Smooke Praw, Anthony P Heaney
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