Familial SDHA mutation associated with pituitary adenoma and pheochromocytoma/paraganglioma.
CONTEXT Reports of the coexistence of pituitary adenomas and pheochromocytoma/paraganglioma are uncommon. Recently germline mutations in 2 of the genes encoding succinate dehydrogenase, SDHC and SDHD, were associated with pituitary tumors.
T. Dwight+7 more
semanticscholar +1 more source
Residual Tumor Confers a 10-Fold Increased Risk of Regrowth in Clinically Nonfunctioning Pituitary Tumors. [PDF]
ObjectiveWe evaluated tumor recurrence and regrowth rates following endoscopic transnasal transsphenoidal (TNTS) surgical removal in a consecutive series of clinically nonfunctioning pituitary adenomas (CNFTs).DesignRetrospective chart review of clinical,
Bergsneider, Marvin+10 more
core +1 more source
Parathyroid localization [PDF]
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B.+7 more
core +1 more source
Higher risk and earlier onset glaucoma in Cushing's syndrome
Abstract Purpose Glaucoma incidence in patients with endogenous Cushing's syndrome (CS) has never been established. We aim to assess the risk for glaucoma among CS patients compared to controls and determine the age of disease onset. Methods A nationwide retrospective matched‐cohort study of patients with endogenous CS diagnosed between 2000 and 2023 ...
Yael Sharon+7 more
wiley +1 more source
Stability and Hopf bifurcation analysis for the hypothalamic-pituitary-adrenal axis model with memory [PDF]
This paper generalizes the existing minimal model of the hypothalamic-pituitary-adrenal (HPA) axis in a realistic way, by including memory terms: distributed time delays, on one hand and fractional-order derivatives, on the other hand. The existence of a unique equilibrium point of the mathematical models is proved and a local stability analysis is ...
arxiv +1 more source
Thyroxine-binding globulin: investigation of microheterogeneity [PDF]
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland+4 more
core +1 more source
Prevalence of Metabolic‐Associated Steatotic Liver Disease in Patients With Primary Aldosteronism
ABSTRACT Objective To assess the prevalence of metabolic associated steatotic liver disease (MASLD) in patients with primary aldosteronism (PA) compared to benign adrenal adenomas, and to evaluate the impact of hormonal excess in inducing MASLD. Design Single‐centre retrospective study. Methods Hepatic steatosis was assessed by liver/spleen (L/S) ratio
Irene Tizianel+6 more
wiley +1 more source
Stability and Hopf bifurcation analysis of a four-dimensional hypothalamic-pituitary-adrenal axis model with distributed delays [PDF]
A four-dimensional mathematical model of the hypothalamus-pituitary-adrenal (HPA) axis is investigated, incorporating the influence of the GR concentration and general feedback functions. The inclusion of distributed time delays provides a more realistic modeling approach, since the whole past history of the variables is taken into account.
arxiv +1 more source
Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]
The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo+11 more
core +1 more source
Ocular Neuromyotonia—A Rare but Reversible Cause of Intermittent Diplopia
Movement Disorders Clinical Practice, EarlyView.
Parthvi Ravat+4 more
wiley +1 more source