Results 11 to 20 of about 357,085 (357)

Systematic analysis based on the cuproptosis-related genes identifies ferredoxin 1 as an immune regulator and therapeutic target for glioblastoma

open access: yesBMC Cancer, 2023
Glioblastoma multiforme (GBM) is recognized as the prevailing malignant and aggressive primary brain tumor, characterized by an exceedingly unfavorable prognosis.
Lirui Dai   +3 more
doaj   +1 more source

Exosomal miRNA Profiling is a Potential Screening Route for Non-Functional Pituitary Adenoma

open access: yesFrontiers in Cell and Developmental Biology, 2022
Non-functional pituitary adenomas (NFPAs) are one of the most prevalent pituitary adenoma subtypes. The lack of reliable screening approach for NFPAs for the insidious clinical course usually leads to delays in medical therapy and consequently worse ...
Liang Lyu   +9 more
doaj   +1 more source

Comprehensive In Silico Analysis of a Novel Serum Exosome-Derived Competitive Endogenous RNA Network for Constructing a Prognostic Model for Glioblastoma

open access: yesFrontiers in Oncology, 2021
PurposeGlioblastoma (GBM) is one of the most aggressive brain tumors with high mortality, and tumor-derived exosomes provide new insight into the mechanisms of GBM tumorigenesis, metastasis and therapeutic resistance.
Zihao Wang   +12 more
doaj   +1 more source

A case of hypogonadtropic hypogonadism due to hypophysitis discovered by secondary male infertility

open access: yesIJU Case Reports, Volume 6, Issue 1, Page 51-53, January 2023., 2023
Introduction The main causes of secondary male infertility are varicocele and aging. It is rarely caused by adult‐onset hypopituitarism. The onset of hypopituitarism is often due to brain tumors, trauma, surgery, or congenital disorders. Case presentation A 29‐year‐old man was admitted to the hospital with complaints of decreased libido and semen ...
Masatoshi Konishi   +8 more
wiley   +1 more source

How to Classify and Define Pituitary Tumors: Recent Advances and Current Controversies

open access: yesFrontiers in Endocrinology, 2021
Pituitary tumors are very complex and heterogeneous and have a very wide range of proliferative and aggressive behaviors, and how to define and classify these tumors remains controversial.
Congxin Dai   +8 more
doaj   +1 more source

Markers for internal neoplasia in the horse

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 132-143, January 2023., 2023
The measurement of tumour markers in horses should be performed only in risk groups or in patients with suspicious clinical/laboratory findings (paraneoplastic syndromes). The results should be interpreted with caution as many factors (e.g., young age, pregnancy and inflammation) affect their concentration or activity.
Karolina Drozdzewska, Heidrun Gehlen
wiley   +1 more source

Preoperative and postoperative blood testosterone levels in patients with acromegaly: a prospective study

open access: yesFrontiers in Endocrinology, 2023
PurposeTo investigate the prevalence of low blood testosterone level (LTL) and its determinant factors among active male acromegaly patients, as well as the effect of surgery on LTL in male acromegaly patients.MethodsA retrospective, single-center study ...
Duoxing Zhang   +16 more
doaj   +1 more source

Predictive value of pituitary tumor morphology on outcomes and complications in endoscopic transsphenoidal surgery

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 8, Issue 4, Page 321-329, December 2022., 2022
Abstract Purpose Endoscopic transsphenoidal surgery (ETSS) is an increasingly utilized approach for resection of pituitary tumors. Prior studies have evaluated preoperative tumor size, location, and extent as prognostic factors for surgical resection. There is little data on the relationship between preoperative pituitary tumor radiographic morphology ...
Andrew T. Heffernan   +8 more
wiley   +1 more source

Clinical Characteristics of Pediatric Patients With Sellar and Suprasellar Lesions Who Initially Present With Central Diabetes Insipidus: A Retrospective Study of 55 Cases From a Large Pituitary Center in China

open access: yesFrontiers in Endocrinology, 2020
Purpose: To increase knowledge for the early differential diagnosis and accurate therapeutic strategies for pediatric patients with sellar or suprasellar region (SSR) lesions who initially present with central diabetes insipidus (CDI).Methods: This is a ...
Xin Ji   +16 more
doaj   +1 more source

Sub-macroscopic skin presentation of acromegaly and effect of pituitary tumor surgery: A study using dermatoscopy and ultra-high-frequency ultrasound

open access: yesFrontiers in Endocrinology, 2023
ObjectiveExcessive growth hormone and insulin-like growth factor 1 contribute to cutaneous changes in acromegaly. We investigated the sub-macroscopic skin manifestation of acromegaly patients and explored its reversibility upon hormone reduction after ...
Xiaopeng Guo   +7 more
doaj   +1 more source

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