Results 21 to 30 of about 357,085 (357)
PurposeStudies on hyperprolactinemia and hypopituitarism in acromegaly are limited. We aimed to analyze the preoperative status, postoperative alterations, and correlated factors of hyperprolactinemia and hypopituitarism in acromegaly patients ...
Xiaopeng Guo+57 more
doaj +1 more source
Purpose: Alternative splicing (AS) was reported to play a vital role in development and progression of glioblastoma (GBM), the most common and fatal brain tumor. Systematic analysis of survival-associated AS event profiles and prognostic prediction model
Zihao Wang+13 more
doaj +1 more source
In the pituitary sella, the coexistence of pituitary adenoma and primary pituitary lymphoma is exceedingly rare. Thus far, only six cases have been reported. Here, we present the seventh case of coexisting pituitary adenoma and primary pituitary lymphoma,
Shangjun Ren+6 more
doaj +1 more source
Integration of an enhanced recovery after surgery program for patients undergoing pituitary surgery
Abstract Evidence‐based enhanced recovery after surgery (ERAS) programs aim to improve patient outcomes and shorten hospital stays. The objective of this study is to describe the development, implementation, and evolution of an ERAS protocol to optimize the perioperative management for patients undergoing endoscopic skull base surgery for pituitary ...
Stephanie Flukes+9 more
wiley +1 more source
A Rare Case of ACTH-Secreting Pituitary Adenoma in a Pediatric Patient. Diagnosis and Management: Case Report and Literature Review. [PDF]
ABSTRACT Due to its rare incidence, pituitary adenoma requires high vigilance and suspicion. Therefore, physicians should consider this differential diagnosis and perform the necessary workup, such as an overnight or standard dexamethasone suppression test and brain magnetic resonance imaging (MRI), to rule it out if sudden hormonal changes without any
Niliyeh S+4 more
europepmc +2 more sources
Leptomeningeal Seeding of Pituitary Adenoma in a Young Lady With Neglected Gigantism: An Extremely Rare Case Report. [PDF]
ABSTRACT Pituitary neuroendocrine tumors can sometimes present with leptomeningeal seeding at their initial diagnosis, emphasizing the need for thorough evaluation in cases of leptomeningeal involvement. Additionally, it is crucial for general physicians to inquire about a patient's menstrual status, particularly in low socioeconomic conditions, as ...
Bagherzadeh S+3 more
europepmc +2 more sources
Cytokeratin 13 (CK13) expression in cancer: a tissue microarray study on 10,439 tumors
Cytokeratin 13 (CK13) is a type I acidic low molecular weight cytokeratin, which is mainly expressed in urothelium and in the squamous epithelium of various sites of origin. Loss of CK13 has been implicated in the development and progression of squamous epithelial neoplasms. To comprehensively determine CK13 expression in normal and neoplastic tissues,
Maximilian Lennartz+25 more
wiley +1 more source
Sex difference in patients with controlled acromegaly—A multicentre survey
Abstract Objective Active acromegaly is subject to sex differences in growth hormone (GH) and Insulin like growth factor 1 (IGF‐I) patterns as well as clinical features but whether this also pertains to controlled disease is unclear. Design In a cross‐sectional, multi‐centre study, 84 patients with acromegaly (F = 43, M = 41), who were considered ...
Jakob Dal+9 more
wiley +1 more source
The Epigenomics of Pituitary Adenoma [PDF]
Background: The vast majority of pituitary tumors are benign and behave accordingly; however, a fraction are invasive and are more aggressive, with a very small fraction being frankly malignant. The cellular pathways that drive transformation in pituitary neoplasms are poorly characterized, and current classification methods are not reliable correlates
Ian F. Dunn+4 more
openaire +4 more sources
Preoperative medical treatments and surgical approaches for acromegaly: A systematic review
Abstract Objective Acromegaly is a condition characterized by an overproduction of growth hormone which infers high morbidity and mortality if left untreated. The objective of this review is to analyse and appraise the current evidence for the generalized use of preoperative medications and the various surgical approaches as described in the literature.
Christos Papaioannou, Maralyn Druce
wiley +1 more source