Results 1 to 10 of about 9,522,905 (293)
Phosphodiesterases and cAMP Pathway in Pituitary Diseases [PDF]
Frontiers in Endocrinology, 2019 Human phosphodiesterases (PDEs) comprise a complex superfamily of enzymes derived from 24 genes separated into 11 PDE gene families (PDEs 1–11), expressed in different tissues and cells, including heart and brain.
Mariana Ferreira Bizzi +4 more
doaj +3 more sources
Hypothalamic-Pituitary Diseases and Erectile Dysfunction. [PDF]
J Clin Med, 2021 Several hormones contribute to ensure penile erection, a neurovascular phenomenon in which nitric oxide plays a major role. Erectile dysfunction (ED), which is defined as the persistent inability to obtain or maintain penile erection sufficient for a ...
Salvio G +4 more
europepmc +2 more sources
Pilot Findings on SARS-CoV-2 Vaccine-Induced Pituitary Diseases: A Mini Review from Diagnosis to Pathophysiology. [PDF]
Vaccines (Basel), 2022 Since the emergence of the COVID-19 pandemic at the end of 2019, a massive vaccination campaign has been undertaken rapidly and worldwide. Like other vaccines, the COVID-19 vaccine is not devoid of side effects.
Taieb A, Mounira EE.
europepmc +2 more sources
Pituitary Diseases and Bone [PDF]
Endocrine Reviews, 2018 Neuroendocrinology of bone is a new area of research based on the evidence that pituitary hormones may directly modulate bone remodeling and metabolism. Skeletal fragility associated with high risk of fractures is a common complication of several pituitary diseases such as hypopituitarism, Cushing disease, acromegaly, and hyperprolactinemia.
Mazziotti, Gherardo +2 more
openaire +4 more sources
Mortality in Patients with Pituitary Disease [PDF]
Endocrine Reviews, 2010 Pituitary disease is associated with increased mortality predominantly due to vascular disease. Control of cortisol secretion and GH hypersecretion (and cardiovascular risk factor reduction) is key in the reduction of mortality in patients with Cushing’s disease and acromegaly, retrospectively.
Mark Sherlock +2 more
exaly +4 more sources
Clinical characteristics and comparative analysis of PD-1/PD-L1 inhibitor-induced pituitary dysfunction versus other pituitary disorders [PDF]
Scientific ReportsThis study aims to investigate the clinical characteristics of programmed cell death protein-1 (PD-1) or programmed cell death ligand-1 (PD-L1) inhibitors-induced pituitary injury (pituitary-irAE) by comparing with other pituitary diseases.
Yan Xiao +9 more
doaj +2 more sources
Brain and Spine, 2022 BackgroundSurgical and clinical management of craniopharyngiomas is associated with high long-term morbidity especially in the case of hypothalamic involvement. Improvements in knowledge of craniopharyngioma molecular biology may offer the possibility of
F. Calvanese +7 more
doaj +3 more sources
罕见病研究, 2023 Cushing′s syndrome(CS)is a clinical syndrome caused by a variety of causes, with main manifestations exhibited by central obesity, purple skin striae, hypertension, and diabetes. In patients with adrenocorticotropic hormone(ACTH)-dependent CS, the result
Chinese Medical Association Rare Diseases Branch, Hypothalamic and Pituitary Disease Group of China Alliance of Rare Diseases (CARD) +1 more
doaj +1 more source
Hyponatremia and Oxidative Stress
Antioxidants, 2021 Hyponatremia, i.e., the presence of a serum sodium concentration ([Na+]) < 136 mEq/L, is the most frequent electrolyte imbalance in the elderly and in hospitalized patients. Symptoms of acute hyponatremia, whose main target is the central nervous system,
Benedetta Fibbi +4 more
doaj +1 more source