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Phosphodiesterases and cAMP Pathway in Pituitary Diseases [PDF]

open access: yesFrontiers in Endocrinology, 2019
Human phosphodiesterases (PDEs) comprise a complex superfamily of enzymes derived from 24 genes separated into 11 PDE gene families (PDEs 1–11), expressed in different tissues and cells, including heart and brain.
Mariana Ferreira Bizzi   +4 more
doaj   +4 more sources

Pituitary Diseases and Bone [PDF]

open access: yesEndocrine Reviews, 2018
Neuroendocrinology of bone is a new area of research based on the evidence that pituitary hormones may directly modulate bone remodeling and metabolism. Skeletal fragility associated with high risk of fractures is a common complication of several pituitary diseases such as hypopituitarism, Cushing disease, acromegaly, and hyperprolactinemia.
Gherardo Mazziotti   +2 more
exaly   +3 more sources

The Relationship Between Pituitary Axis Hormones and All-Cause Mortality in Hospitalized Patients with Chronic Diseases: A Prospective Cohort Study [PDF]

open access: yesMedicina
Background and Objectives: The pituitary gland plays a central role in endocrine regulation, and chronic illnesses may disrupt pituitary axis function, potentially influencing clinical outcomes.
Esin Havare   +4 more
doaj   +2 more sources

Expert Consensus on Bilateral Inferior Petrosal Sinus Sampling in the Diagnosis of Cushing′s Syndrome (2023)

open access: yes罕见病研究, 2023
Cushing′s syndrome(CS)is a clinical syndrome caused by a variety of causes, with main manifestations exhibited by central obesity, purple skin striae, hypertension, and diabetes. In patients with adrenocorticotropic hormone(ACTH)-dependent CS, the result
Chinese Medical Association Rare Diseases Branch, Hypothalamic and Pituitary Disease Group of China Alliance of Rare Diseases (CARD)   +1 more
doaj   +1 more source

Hyponatremia and Oxidative Stress

open access: yesAntioxidants, 2021
Hyponatremia, i.e., the presence of a serum sodium concentration ([Na+]) < 136 mEq/L, is the most frequent electrolyte imbalance in the elderly and in hospitalized patients. Symptoms of acute hyponatremia, whose main target is the central nervous system,
Benedetta Fibbi   +4 more
doaj   +1 more source

Endoscopy in pituitary diseases

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
The etiology pattern of pituitary diseases is diverse and complex, including pituitary adenoma, Rathke cleft cyst (RCC), pituitary apoplexy, craniopharyngioma, etc.
ZHU Jian⁃yu   +2 more
doaj   +1 more source

Sub-macroscopic skin presentation of acromegaly and effect of pituitary tumor surgery: A study using dermatoscopy and ultra-high-frequency ultrasound

open access: yesFrontiers in Endocrinology, 2023
ObjectiveExcessive growth hormone and insulin-like growth factor 1 contribute to cutaneous changes in acromegaly. We investigated the sub-macroscopic skin manifestation of acromegaly patients and explored its reversibility upon hormone reduction after ...
Xiaopeng Guo   +7 more
doaj   +1 more source

Best Achievements in Pituitary and Adrenal Diseases in 2020 [PDF]

open access: yesEndocrinology and Metabolism, 2021
Significant progress in pituitary and adrenal diseases was made in 2020. This review presents major translational and clinical advances in research on pituitary and adrenal diseases, encompassing their epidemiology, pathogenesis, diagnosis, and clinical ...
Chang Ho Ahn, Jung Hee Kim
doaj   +1 more source

Pituitary disease: An update

open access: yesAustralian Journal of General Practice, 2021
Pituitary lesions are present in >10% of the population. Approximately one in 1000 people has a symptomatic pituitary tumour, which may cause clinical problems from mass effect, hormonal hypersecretion and impairment of normal pituitary function.The aim of this article is to outline the potential causes of a sellar and parasellar mass, with an emphasis
Inder, Warrick J., Jang, Christina
openaire   +5 more sources

Neoadjuvant B-RAF and MEK inhibitor targeted therapy for adult papillary craniopharyngiomas: a new treatment paradigm

open access: yesBrain and Spine, 2022
BackgroundSurgical and clinical management of craniopharyngiomas is associated with high long-term morbidity especially in the case of hypothalamic involvement. Improvements in knowledge of craniopharyngioma molecular biology may offer the possibility of
F. Calvanese   +7 more
doaj   +3 more sources

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