Results 101 to 110 of about 149,054 (297)

Pathogen burden and cortisol profiles over the day [PDF]

open access: yes, 2009
Hypothalamic-pituitary-adrenocortical (HPA) regulation in adults is influenced by early psychosocial adversity, but the role of infectious disease history is poorly understood.
Steptoe, A   +6 more
core   +1 more source

Human Pituitary Organoids: Transcriptional Landscape Deciphered by scRNA‐Seq and Stereo‐Seq, with Insights into SOX3's Role in Pituitary Development

open access: yesAdvanced Science
The 3D human pituitary organoid represents a promising laboratory model for investigating human pituitary diseases. Nonetheless, this technology is still in its nascent stage, with uncertainties regarding the cellular composition, intercellular ...
Shengjie Wang   +8 more
doaj   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

open access: yesAnimal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad   +7 more
wiley   +1 more source

Clinical and hormonal characteristics of patients with different types of hypophysitis: a single-center experience

open access: yesArchives of Endocrinology and Metabolism
Objective: The inflammation of the pituitary gland is known as hypophysitis. It is a rare disease accounting for approximately 0.24%-0.88% of all pituitary diseases. The natural course of hypophysitis is variable. Main forms are histologically classified
Narin Nasiroglu Imga   +3 more
doaj   +1 more source

A Mouse Model of Depression‐Tumor Multimorbidity Reveals the Mechanism of Tumor Growth Accelerated by Depression

open access: yesAnimal Research and One Health, EarlyView.
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren   +6 more
wiley   +1 more source

Biportal Endoscopic Posterior Open‐Window Focal Debridement and Lavage for Sacroiliac Joint Tuberculosis

open access: yesArthroscopy Techniques, EarlyView.
Abstract Sacroiliac joint tuberculosis (SJT), although relatively uncommon, may lead to severe destruction and functional impairment of the sacroiliac joint. Surgical intervention is recommended for patients with significant joint destruction, mild cystic changes, or sacroiliac joint instability. Early bone fusion may be facilitated through drainage of
Wei Cheng   +3 more
wiley   +1 more source

Evaluation of antioxidants systems in pituitary-adrenal axis diseases. [PDF]

open access: yes, 2010
The role of adrenal steroids in antioxidant regulation is not known. Previously, we demonstrated some Coenzyme Q(10) (CoQ(10)) alterations in pituitary diseases, which can induce complex pictures due to alterations of different endocrine axes.
Pontecorvi, Alfredo   +6 more
core  

Blood DNA methylation of CRF and its association with amygdala volume and mood in Cushing’s syndrome

open access: yesFrontiers in Epigenetics and Epigenomics
ObjectiveThe impact of chronic exposure to stress or glucocorticoids on psychiatric symptoms has been exemplified by cases of iatrogenic or endogenous hypercortisolism such as Cushing’s syndrome (CS).
Richard S. Lee   +13 more
doaj   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

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