Results 201 to 210 of about 148,544 (297)

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Identification of a novel THRB mutation causing thyroid hormone resistance syndrome. [PDF]

Arch Endocrinol Metab
Yang J, Wang C, Quan L, Jiang S.
europepmc   +1 more source

Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone

Pediatric Investigation, EarlyView.
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu, Ningyi Song, Yue Zhao, Caiqi Du, Yuning Zhao, You Wu, Xiaoping Luo   +6 more
wiley   +1 more source

Changing understanding of acromegaly epidemiology and early mortality risk.

J Clin Endocrinol Metab
Esposito D, Johannsson G.
europepmc   +1 more source

Calcaneal quantitative ultrasound parameters strongly correlate with DXA measurements in patients with acromegaly. [PDF]

Pituitary
Campana C, Casabella A, Arecco A, Cutolo M, Tonelli S, Hysa E, Vera L, Bertaina F, Amarù J, Ferone D, Paolino S, Gatto F.   +11 more
europepmc   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

Pediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu, Jing Wei, Chen Liu, Pengpeng Wang, Wentong Ge, Yang Han   +5 more
wiley   +1 more source

Current treatment landscape of acromegaly.

J Clin Endocrinol Metab
Castinetti F, Ioachimescu AG.
europepmc   +1 more source

Ageing and pituitary neuroendocrine tumours (PitNETs): from bench to bedside. [PDF]

Endocr Relat Cancer
De Alcubierre D, Carbonara F, Feola T, Gianno F, Minniti G, Esposito V, Jaffrain-Rea ML.   +6 more
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

The Real-World Endocrine Toxicity Profile of ICIs, VEGFR-TKIs, and Their Combination: Analysis of the FDA Adverse Event Reporting System (FAERS) Database. [PDF]

Oncol Res
Marrano N, Caporusso M, Matino C, Caruso I, Ganini C, Rizzo M, Di Gioia L, Cignarelli A, Perrini S, Laviola L, Porta C, Giorgino F, Natalicchio A.   +12 more
europepmc   +1 more source