Results 61 to 70 of about 148,544 (297)

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

Pituitary Diseases and COVID-19 Outcomes in South Korea: A Nationwide Cohort Study [PDF]

J Clin Med, 2023
Ha J, Kim KM, Lim D, Song K, Seo GH.
europepmc   +2 more sources

Central Hypothyroidism with Low TSH Compared to Normal TSH Is Associated with More Advanced Pituitary Disease and Less Favorable Metabolic Profile

Metabolites
Background: Central hypothyroidism is characterized by either decreased TSH or, more commonly, normal TSH. This study aims to check whether this biochemical difference related to the severity of the pituitary disease, metabolic processes and general well-
Aleksandra E. Matusiak, Jan Stępniak, Krzysztof C. Lewandowski, Andrzej Lewiński, Małgorzata Karbownik-Lewińska   +4 more
doaj   +1 more source

Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review

BMC Endocrine Disorders, 2021
Background Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual.
Yi Zhang, Cheng Chen, Min Lin, Kan Deng, Huijuan Zhu, Wenbin Ma, Hui Pan, Renzhi Wang, Yong Yao   +8 more
doaj   +1 more source

Pituitary diseases and sleep disorders

, 2016
Patients with pituitary diseases have decreased quality of life. Sleep disorders are prevalent among patients with pituitary diseases and contribute to decreased quality of life. Patients previously treated for compression of the optic chiasm by surgery,
Johannes A. Romijn, Romijn, Johannes A.
core   +1 more source

The Pituitary Gland

, 2023
This book, The Pituitary Gland - An Overview of Pathophysiology and Current Management Techniques, provides a comprehensive overview of key pituitary diseases and their profound impact across a diverse spectrum of medical disciplines.

core   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Pituitary metastases as a rare variant of intracranial metastasis

Бюллетень сибирской медицины, 2008
Metastatiс spread of neoplasms to the pituitary gland is a relatively common finding in autopsy series of cancer patients. The majority of these patients were asymptomatic.
A. V. Osnitskaya, V. Ye. Olyushin
doaj   +1 more source

Mortality in Patients with Pituitary Disease [PDF]

Endocrine Reviews, 2010
Pituitary disease is associated with increased mortality predominantly due to vascular disease. Control of cortisol secretion and GH hypersecretion (and cardiovascular risk factor reduction) is key in the reduction of mortality in patients with Cushing’s disease and acromegaly, retrospectively.
Sherlock, Mark, Ayuk, John, Tomlinson, Jeremy W, Toogood, Andrew A, Aragon-Alonso, Aurora, Sheppard, Michael C, Bates, Andrew S, Stewart, Paul M   +7 more
openaire   +3 more sources

Hyperprolactinemia in a male pituitary androgen receptor knockout mouse is associated with female‐like lactotroph development

, 2021
Background: Circulating prolactin concentration in rodents and humans is sexually dimorphic. Oestrogens are a well-characterised stimulator of prolactin release.
Christian, HC, Le Tissier, P, Smith, LB, Helen C. Christian, O’Hara, L, Paul Le Tissier, Lee B. Smith, Laura O’Hara   +7 more
core   +1 more source