Results 61 to 70 of about 2,352,806 (292)

Characterization of Human Pituitary Adenomas in Cell Cultures by Light And Electron Microscopic Morphology And Immunolabeling [PDF]

, 2005
The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens.
Bácsy, Ernő, Hegedűs, Balázs, Slowik, Felicia, Bálint, Katalin, Pásztor, Emil, Kerekes, Edit, Fazekas, Ilona   +6 more
core   +1 more source

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source

Pituitary dysfunction in infective brain diseases

Indian Journal of Endocrinology and Metabolism, 2013
Infectious diseases of the central nervous system (CNS) are increasingly being recognized as important causes of hypopituitarism. Although tuberculosis is the most common agent involved, non-mycobacterial agents like viruses, bacteria, fungus, and ...
Anne M Beatrice, Chitra Selvan, Satinath Mukhopadhyay   +2 more
doaj   +1 more source

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

Advanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha, Di Feng, Ziru Xue, Zhiying Liu, Xiaochen Lin, Zhe Wang, Ling Xu, Jasper Fuk Woo Chan, Martin Cheung, Michael Shing Yan Huen, Yusong Guo, Kui Ming Chan, Yun Liu, Bo Gao   +13 more
wiley   +1 more source

The clinical characteristics and gene mutations associated with thyroid hormone resistance syndrome coexisting with pituitary tumors

Frontiers in Endocrinology, 2023
AimsResistance to thyroid hormone (RTH) and pituitary tumors are both rare diseases, and the differential diagnosis of these two diseases is difficult in some cases. There are also patients who have both conditions, making diagnosis more difficult.
Junyu Zhao, Lusi Xu, Chunyu Li, Fei Wang, Lin Liao, Jianjun Dong   +5 more
doaj   +1 more source

Pituitary acromegaly: not one disease [PDF]

Endocrine-Related Cancer, 2017
Acromegaly has traditionally been regarded as a monomorphous disorder resulting from a benign pituitary adenoma. Increasing evidence, however, is highlighting that this disorder is associated with a spectrum of morphologically distinct pituitary tumors with variable clinical, biochemical and radiologic features and differing therapeutic outcomes that ...
Sylvia L, Asa, Walter, Kucharczyk, Shereen, Ezzat   +2 more
openaire   +2 more sources

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Feasibility of transition research in pituitary disease using patient registries: a EuRREB secondary survey

Endocrine Connections
Aim: Rare disease registries focusing on natural history provide an opportunity to understand the transition process for rare endocrine conditions, including pituitary diseases. This study aims to assess the feasibility of using the European Registry for
Savi Shishkov, Violeta Iotova, Iris Pelsma, Ana Luisa Priego Zurita, Nienke Biermasz, Faisal Ahmed   +5 more
doaj   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Depression and Anxiety States of Patients Followed in Pituitary Polyclinic

Gazi Medical Journal
Objective: Individuals with pituitary disease are susceptible to the development of depression and anxiety because of interventional therapies, such as surgery and radiotherapy (RT), and long-term medical care (due to hyper or hypofunction).
Afruz Babayeva, Mehmet Muhittin Yalçın, Atakan Tüm, Aydın Tuncer Sel, Alev Eroğlu Altınova, Müjde Aktürk, Mehmet Ayhan Karakoç, İlhan Yetkin, Füsun Törüner   +8 more
doaj   +1 more source