Results 11 to 20 of about 7,016 (204)

Pituitary Dwarfism and Adrenocorticotropic Hormone Deficiency in a White Swiss Shepherd Dog With LHX3 Mutation [PDF]

Journal of Veterinary Internal Medicine
LHX3 mutation in dogs is associated with combined pituitary hormone deficiency. However, ACTH secretion is usually preserved. A 9‐week‐old female White Swiss Shepherd dog presented with growth retardation and was diagnosed with pituitary dwarfism due to ...
Gaëlle Schils, Lisa Stammeleer, Sylvie Daminet   +2 more
doaj   +3 more sources

A contracted DNA repeat in LHX3 intron 5 is associated with aberrant splicing and pituitary dwarfism in German shepherd dogs. [PDF]

PLoS ONE, 2011
Dwarfism in German shepherd dogs is due to combined pituitary hormone deficiency of unknown genetic cause. We localized the recessively inherited defect by a genome wide approach to a region on chromosome 9 with a lod score of 9.8.
Annemarie M W Y Voorbij, Frank G van Steenbeek, Manon Vos-Loohuis, Ellen E C P Martens, Jeanette M Hanson-Nilsson, Bernard A van Oost, Hans S Kooistra, Peter A Leegwater   +7 more
doaj   +4 more sources

Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature [PDF]

Case Reports in Dentistry, 2017
Hypopituitarism is a disorder caused by a reduced level of trophic hormones that may be consequent on different destructive processes. The clinical manifestations depend on the type of hormone involved.
Franco Ferrante, Sergio Blasi, Rolando Crippa, Francesca Angiero   +3 more
doaj   +2 more sources

Treatment of a femoral neck fracture in a patient with dwarfism: a case report [PDF]

BMC Musculoskeletal Disorders
Background Femoral neck fractures in patients with pituitary dwarfism present significant surgical challenges due to anatomical variations, compromised bone quality, and limited therapeutic options.
Junyan Zhao, Liuliu Chen, Kun He, Muyao Li, Zhenwen Li, Hui Lin, Songjun Li   +6 more
doaj   +2 more sources

Pituitary stalk interruption syndrome (PSIS): do not miss this diagnosis

The Egyptian Journal of Radiology and Nuclear Medicine, 2022
Background Pituitary stalk interruption syndrome (PSIS) is one of the rare endocrinal aetiologies of the abnormal short stature. This is a syndrome characterized by a specific tirade, an absent or hypoplastic anterior pituitary gland, thin or absent ...
Mahmoud Agha, Maha Sallam Mohammed Sallam, Ahmed M. Abougabal, Mohamed Saied Abdelgawad   +3 more
doaj   +1 more source

Snow White and the Seven Dwarfs: a fairytale for endocrinologists

Endocrine Connections, 2021
‘Snow White and the Seven Dwarfs’, a fairytale that is widely known across the Western world, was originally written by the Brothers Grimm, and published in 1812 as ‘Snow White’.
Athanasios Zervas, George Chrousos, Sarantis Livadas   +2 more
doaj   +1 more source

Diagnosis and Treatment of Growth Hormone Deficiency: A Position Statement from Korean Endocrine Society and Korean Society of Pediatric Endocrinology [PDF]

Endocrinology and Metabolism, 2020
Growth hormone (GH) deficiency is caused by congenital or acquired causes and occurs in childhood or adulthood. GH replacement therapy brings benefits to body composition, exercise capacity, skeletal health, cardiovascular outcomes, and quality of life ...
Jung Hee Kim, Hyun Wook Chae, Sang Ouk Chin, Cheol Ryong Ku, Kyeong Hye Park, Dong Jun Lim, Kwang Joon Kim, Jung Soo Lim, Gyuri Kim, Yun Mi Choi, Seong Hee Ahn, Min Ji Jeon, Yul Hwangbo, Ju Hee Lee, Bu Kyung Kim, Yong Jun Choi, Kyung Ae Lee, Seong-Su Moon, Hwa Young Ahn, Hoon Sung Choi, Sang Mo Hong, Dong Yeob Shin, Ji A Seo, Se Hwa Kim, Seungjoon Oh, Sung Hoon Yu, Byung Joon Kim, Choong Ho Shin, Sung-Woon Kim, Chong Hwa Kim, Eun Jig Lee   +30 more
doaj   +1 more source

The dwarf phenotype in GH240B mice, haploinsufficient for the autism candidate gene Neurobeachin, is caused by ectopic expression of recombinant human growth hormone. [PDF]

PLoS ONE, 2014
Two knockout mouse models for the autism candidate gene Neurobeachin (Nbea) have been generated independently. Although both models have similar phenotypes, one striking difference is the dwarf phenotype observed in the heterozygous configuration of the ...
Kim Nuytens, Krizia Tuand, Quili Fu, Pieter Stijnen, Vincent Pruniau, Sandra Meulemans, Hugo Vankelecom, John W M Creemers   +7 more
doaj   +1 more source

Wellbeing, quality of life, presence of concurrent diseases, and survival times in untreated and treated German Shepherd dogs with dwarfism

PLoS ONE, 2021
Background Pituitary dwarfism (PD) in German Shepherd dogs (GSD) is a rare endocrinopathy. Cause and inheritance of the disease are well characterized, but the overall survival time, presence of concurrent diseases, quality of life (QoL) and influence of
Stefanie Kitzmann, Katrin Hartmann, Yury Zablotski, Anna Rieger, Ralf Mueller, Astrid Wehner   +5 more
doaj   +2 more sources

Dwarfism with joint laxity in Friesian horses is associated with a splice site mutation in B4GALT7 [PDF]

, 2016
Background: Inbreeding and population bottlenecks in the ancestry of Friesian horses has led to health issues such as dwarfism. The limbs of dwarfs are short and the ribs are protruding inwards at the costochondral junction, while the head and back ...
Back, Willem, Bastiaansen, John WM, Boegheim, Iris J, Dibbits, Bert W, Ducro, Bart J, Hellinga, Ids, Leegwater, Peter A, Monroe, Glen R, Nijman, Isaac J, Schurink, Anouk, van de Goor, Leanne H, van Steenbeek, Frank G, Vos-Loohuis, Manon   +12 more
core   +7 more sources