ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
Development of the anterior pituitary: diverse lineages of the stem/progenitor cells
The pituitary gland is endocrine tissue composed of two distinct parts with different origins: the adenohypophysis (adenohypophyseal placode origin) and the neurohypophysis (neuroectoderm origin). Differentiation of endocrine cells in the pituitary gland
Yukio Kato, Takako Kato
doaj +1 more source
Gastrointestinal strictures in a pediatric patient with Satoyoshi syndrome
Abstract We present a novel case of gastrointestinal strictures in a young girl with Satoyoshi syndrome (SS), highlighting multi‐system features of alopecia universalis, painful muscle cramps with dystonia, aberrant growth velocity, and skeletal abnormalities.
Katherine (Tusia) Pohoreski +5 more
wiley +1 more source
Metastatic Prostate Adenocarcinoma Presenting Central Diabetes Insipidus
The pituitary gland and infundibulum can be involved in a variety of medical conditions, including infiltrative diseases, fungal infections, tuberculosis, and primary and metastatic tumors.
Hakkı Yılmaz +4 more
doaj +1 more source
Expression of three GnRH receptors in specific tissues in male and female sea lampreys Petromyzon marinus at three distinct life stages [PDF]
Two recently cloned gonadotropin-releasing hormone (GnRH) receptors (lamprey GnRH-R-2 and lamprey GnRH-R-3) along with lamprey (l) GnRH-R-1 were shown to share similar structural features and amino acid motifs common to other vertebrate receptors.
Daukss, Dana M. +3 more
core +1 more source
Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson +4 more
wiley +1 more source
Acromegaly Presenting With Cricoarytenoid Joint Arthropathy
Excess growth hormone in acromegaly induces characteristic acral and soft tissue overgrowth (particularly in the face and hands), arthropathies, as well as cardiovascular and metabolic complications. Similar proliferative changes can occur in the larynx, where hypertrophy of the arytenoid and cricoid cartilages may impair vocal fold mobility.
Samantha Salvi Cruz +3 more
wiley +1 more source
The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y. +2 more
core +1 more source
Corticosteroid Exposure in Chronic Rhinosinusitis and Global Airway Disease: Adrenal and Bone Impact
ABSTRACT Objective To investigate cumulative corticosteroid (CC) burden in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), with or without coexisting asthma (global airway disease, GAD), referred for biologic treatment, and to assess the prevalence of CC‐related comorbidities, including secondary adrenal insufficiency, osteopenia and ...
Christiane Haase +7 more
wiley +1 more source
Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis
This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua +3 more
wiley +1 more source

