Results 81 to 90 of about 66,729 (223)

Pituitary Adenoma: A Short Illustrative Review

Indian Journal of Neurosurgery, 2016
The pituitary gland is located below the brain in a depression of sphenoid bone known as sella turcica. It controls most of the body's endocrine functions via the secretion of various hormones into the circulatory system.
Sharada Rane, Anita Kavatkar, Almas Pathan, Shaila Puranik   +3 more
doaj   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Critical roles of endogenous glucocorticoids for disease tolerance in malaria

, 2019
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien, Opdenakker, Ghislain, Van den Steen, Philippe E., Vandermosten, Leen, Vanhorebeek, Ilse   +4 more
core   +1 more source

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

Clinical Anatomy, EarlyView.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley, Brooke Willoughby, Alexandra L. Webb, Natasha A. M. S. Flack, Laura Y. Whitburn   +4 more
wiley   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Clinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol   +4 more
wiley   +1 more source

Two Cases of Pituitary Stalk Interruption Syndrome in Syrian Children

Case Reports in Endocrinology, 2020
Pituitary stalk interruption syndrome (PSIS) is an extremely rare cause of growth failure and delayed puberty. It can be diagnosed by magnetic resonance imaging (MRI) of the hypothalamus and pituitary gland, showing an ectopic or absent posterior ...
Ibrahim Alali, Reem Saad, Younes Kabalan
doaj   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Effect of enhanced plane of nutrition in early life on the transcriptome and proteome of the anterior pituitary gland in Angus heifer calves

BMC Genomics
Background Enhanced nutrition during the early calfhood period has been shown to lead to earlier pubertal development in heifer calves. This is of interest as earlier pubertal onset can subsequently facilitate earlier calving which can economically ...
Kate Keogh, Alan K. Kelly, David A. Kenny   +2 more
doaj   +1 more source

Gene expression patterns in anterior pituitary associated with quantitative measure of oestrous behaviour in dairy cows [PDF]

, 2010
Intensive selection for high milk yield in dairy cows has raised production levels substantially but at the cost of reduced fertility, which manifests in different ways including reduced expression of oestrous behaviour.
Beerda, B., Frijters, A.C.J., Kommadath, A., Mulder, H.A., Pas, M.F.W., te, Smits, M.A., Veerkamp, R.F., Wit, A.A.C., de, Woelders, H.   +8 more
core   +2 more sources

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source