Results 81 to 90 of about 811,244 (395)
Advanced Science, EarlyView.TSHR is highly expressed in differentiated thyroid cancer (DTC), making it an ideal target for adoptive immune cell therapy. A novel Ligand‐based TSH‐CAR‐T cell approach effectively eradicated TSHR‐positive thyroid tumors in vitro and accomplished full remission in tumor models with favorable safety profile, highlighting that TSH‐CAR‐T cells could ...
Fei Wang +10 more
wiley +1 more source
Metastases to the pituitary gland [PDF]
Neurosurgical Focus, 2004 Only 1% of all pituitary surgeries are performed to treat tumors that have metastasized to the pituitary gland; however, in certain cases of malignant neoplasms pituitary metastases do occur. Breast and lung cancers are the most common diseases that metastasize to the pituitary.
William T. Couldwell, Daniel R. Fassett
openaire +2 more sources
Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives
Advanced Science, EarlyView.Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley +1 more source
Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development
JCI Insight, 2020 Pituitary developmental defects lead to partial or complete hormone deficiency and significant health problems. The majority of cases are sporadic and of unknown cause.
Emily J. Lodge +16 more
doaj +1 more source
Preliminary studies on hypophysation technique of induced breeding of Clarias lazera [PDF]
, 1983 Fry supply is still the most serious problem yet to be solved in the culture of Clarias lazera in ponds. The object of the experiment is to compare the effect of fresh pituitary extract with that of the synthetic hormone with a view to determining the ...
Ebietomiye, F.O., Ojo, E.O.
core
Annals of Gastroenterological Surgery, EarlyView.This study investigates the long‐term endocrine and metabolic consequences of ghrelin‐depleted gastrectomy, with a focus on skeletal muscle mass and bone mineral content. Sustained reductions in serum desacyl‐ghrelin were linked to lower IGF‐1 levels, resulting in significant loss of muscle and bone.
Hiroki Harada +9 more
wiley +1 more source
Neurology of the pituitary gland [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1999 This review will focus on those aspects of pituitary disease immediately relevant to neurologists and neurosurgeons when assessing and counselling patients. It is essential to adopt a multidisciplinary approach to the diagnosis and management of pituitary disease as emphasised by the recently published guidelines from the Royal College of Physicians of
John D. Pickard +6 more
openaire +3 more sources
Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts
American Journal of Hematology, EarlyView.ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent +27 more
wiley +1 more source
Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics [PDF]
, 2016 The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are correlated with many stress-related diseases such as post-traumatic stress disorder (
Chou, Tom +2 more
core +3 more sources
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Limited studies have been conducted on pubertal development in populations with pre‐existing medical conditions. More than 20‐fold increased risk of early puberty has been reported in neurodevelopmental disorders; however, this is a heterogeneous group.
Amanda Piring +4 more
wiley +1 more source