Results 101 to 110 of about 28,807 (265)
Eye Darkening Under Dehydration Stress in the Neotropical Frog Boana punctata (Schneider, 1799)
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.Dehydration induces a strong and partially reversible increase in iris pigmentation in the Neotropical frog Boana punctata. The tight relationship between iris darkening and hydration state identifies ocular pigmentation as a simple, non‐invasive physiological biomarker with broad potential for assessing hydric stress in amphibian populations ...
Ricardo Reques +5 more
wiley +1 more source
Journal of Traumatic Stress, EarlyView.Abstract Potentially traumatic events (PTEs) are associated with cardiovascular disease (CVD) in aging populations. Despite sex differences in PTE exposure and CVD incidence, no study has examined sex‐specific associations between PTEs and CVD in the same sample of middle‐aged and older adults.
Jeanine I. Nasser +5 more
wiley +1 more source
The Laryngoscope, EarlyView.Residual and recurrent disease in advanced juvenile nasopharyngeal angiofibromas (JNAs) demonstrate spontaneous involution, reduction in size, or long‐term stability following initial treatment in 95% of patients. In this systematic review of 131 patients with advanced JNA, only 2% of patients demonstrated disease progression during surveillance, but ...
Shivani Angelique Kumar +2 more
wiley +1 more source
Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications
Neuroprotection, EarlyView.Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh +2 more
wiley +1 more source
The Journal of Pathology, EarlyView.Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi +8 more
wiley +1 more source
Pediatric Discovery, EarlyView.Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Pediatric Investigation, EarlyView.This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu +6 more
wiley +1 more source
Sensory Neuroscience, EarlyView.Irritable bowel syndrome (IBS) is associated with dysregulation of the autonomic nervous system and altered brain–gut communication. rTMS may alleviate IBS symptoms by modulating central autonomic and pain‐processing networks, potentially restoring sympathovagal balance and reducing visceral hypersensitivity.
Aliasghar Karimi +4 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Endocrine‐disrupting chemicals (EDCs), such as 17α‐ethinylestradiol (EE2), have raised concerns about their potential effects on aquatic organisms, particularly during early developmental stages. In this context, the study of behavioral disruption has gained considerable attention, as it may have consequences on individual fitness and ...
Soloperto Sofia +6 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida +7 more
wiley +1 more source