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The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral +3 more
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Dietary melatonin and its benefits on cardiovascular disease
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low‐ and middle‐income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti‐inflammatory and immunomodulatory properties that may confer cardiovascular benefits.
Karabo Tisane +2 more
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Hormones of the Anterior Pituitary Body
New England Journal of Medicine, 1965Pituitary Peptides and Fat Mobilization The interrelation of fat mobilization and the pituitary gland has a long history beginning with the observation that hypophysectomy reduces the mobilization ...
H, FRIESEN, E B, ASTWOOD
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Postgraduate Medicine, 1961
The adenohypophyseal hormones influence general body growth and carbohydrate metabolism and exercise direct control on the functions of the adrenal cortex, the thyroid and the gonads. The six known hormones of the anterior pituitary are classified as metabolic and gonadotropic.In describing the biologic properties and physicochemical characteristics of
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The adenohypophyseal hormones influence general body growth and carbohydrate metabolism and exercise direct control on the functions of the adrenal cortex, the thyroid and the gonads. The six known hormones of the anterior pituitary are classified as metabolic and gonadotropic.In describing the biologic properties and physicochemical characteristics of
openaire +2 more sources
Endocrinology, 1931
As our knowledge of endocrine glands increases it becomes more and more evident that the number of active principles is very much greater than had formerly been supposed. The separation of two hormones from the posterior lobe of the pituitary gland (1) stimulated speculation along this line but we must not allow ourselves to jump at the conclusion that
E. P. BUGBEE, A. E. SIMOND, H. M. GRIMES
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As our knowledge of endocrine glands increases it becomes more and more evident that the number of active principles is very much greater than had formerly been supposed. The separation of two hormones from the posterior lobe of the pituitary gland (1) stimulated speculation along this line but we must not allow ourselves to jump at the conclusion that
E. P. BUGBEE, A. E. SIMOND, H. M. GRIMES
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Sensitivity of anterior pituitary hormones to irradiation
Expert Review of Endocrinology & Metabolism, 2006Cranial irradiation is used in the management of a diverse group of intracranial pathologies. However, if any part of the hypothalamic-pituitary axis is included in the radiation field, there is a risk of developing neuroendocrine dysfunction. Growth hormone is the most radiosensitive of the anterior pituitary hormones, followed by the gonadotropins ...
Mark, Sherlock, Andrew A, Toogood
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Anterior Pituitary Hormones in CSF
Archives of Internal Medicine, 1979After the initial report by Linfoot and co-workers in 1970, 1 it has been assumed that an abnormal increase in the concentration of an anterior pituitary hormone in the CSF is indicative of suprasellar extension of the pituitary tumor producing that hormone. The report by Jordan et al in the February issue of theArchives(139:208-211, 1979) and a recent
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Lithosperm inhibition of anterior pituitary hormones
Biochemical and Biophysical Research Communications, 1975Summary A cold-water extract of Lithospermum ruderale was injected into White Leghorn chicks for nine days. Body weights decreased slightly but testes and thyroid weights were markedly depressed. Gonadotropin content of anterior pituitaries of donors given 5.0 mg daily of lithosperm was 300% greater, and in the 10.0 mg donors 2670% greater than ...
W R, Breneman, F J, Zeller
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Analysis of the Copulsatility of Anterior Pituitary Hormones*
The Journal of Clinical Endocrinology & Metabolism, 1991We have used combinatorial algebra and computer simulations to calculate expected means, variances, and probabilities of hormone-peak coincidences in 2 or more endocrine pulse series. We illustrate application of this conditional probability analysis to pulsatile LH, FSH, and/or PRL data. We observed that 1) serum LH and FSH pulses in 14 young men were
J D, Veldhuis, M L, Johnson, E, Seneta
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