Results 21 to 30 of about 28,807 (265)

Panhypopituitarism Due to Hemochromatosis

Endocrinology Research and Practice, 2013
Hemochromatosis is an iron storage disease. Panhypopituitarism is a clinical condition in which the anterior pituitary hormones are deficient. Herein, we report a rare case of panhypopituitarism due to hemochromatosis.
Mesut Özkaya, Kadir Gisi, Ali Çetinkaya, Sedat Köröğlu   +3 more
doaj   +1 more source

Recent advances in anterior pituitary hormones and metabolic-associated fatty liver disease

Frontiers in Endocrinology
The classical theory of the pituitary–target gland axis suggests that the hormones secreted by the pituitary gland only regulate the synthesis and secretion of target gland hormones, while the target gland hormones act on the tissues of the body to ...
Changqing Liu, Yuanyuan Long, Junjun Liu, Junjun Liu, Yongfeng Song, Yongfeng Song, Yongfeng Song, Yongfeng Song   +7 more
doaj   +1 more source

Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis

Acta Neuropathologica Communications, 2021
Pituitary neuroendocrine tumors (PitNETs) are common, generally benign tumors with complex clinical characteristics related to hormone hypersecretion and/or growing sellar tumor mass.
Abdellah Tebani, Jelena Jotanovic, Neda Hekmati, Åsa Sivertsson, Olafur Gudjonsson, Britt Edén Engström, Johan Wikström, Mathias Uhlèn, Olivera Casar-Borota, Fredrik Pontén   +9 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Studies on the Anterior Pituitary Hormones of the Kangaroo

Experimental Biology and Medicine, 1974
SummaryA small quantity of kangaroo pituitaries were subjected to fractionation procedures known to separate mammalian pituitary hormones. These involved (NH4) 2SO4 fractionation, ion-exchange chromatography, and gel filtration. The results show that the kangaroo possesses pituitary hormones which behave very much like their mammalian counterparts with
S W, Farmer, H, Papkoff, C H, Li
openaire   +2 more sources

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source

Clinical Features and Analysis in Pituitary Stalk Interruption Syndrome

International Journal of Endocrinology
Objective. Pituitary stalk interruption syndrome (PSIS) is characterized by the absence of pituitary stalk, pituitary hypoplasia, and ectopic posterior pituitary.
Qiuxuan Guo, Jing Zhao, Shuang Yu
doaj   +1 more source

Pituitary Adenoma: A Short Illustrative Review

Indian Journal of Neurosurgery, 2016
The pituitary gland is located below the brain in a depression of sphenoid bone known as sella turcica. It controls most of the body's endocrine functions via the secretion of various hormones into the circulatory system.
Sharada Rane, Anita Kavatkar, Almas Pathan, Shaila Puranik   +3 more
doaj   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source