Results 31 to 40 of about 1,059,440 (253)
Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells
Nature Communications, 2016 It is difficult to generate functional human anterior pituitary tissues in vitro. Here, Ozone et al. generate human anterior pituitary from embryonic stem cells by recapitulating in vivodevelopment, and demonstrate this tissue secretes hormones and ...
Chikafumi Ozone +8 more
doaj +1 more source
Pituitary stalk interruption syndrome presenting in a euthyroid adult with short stature
Radiology Case Reports, 2018 Pituitary stalk interruption syndrome (PSIS) is a distinct and rare clinical entity responsible for congenital hypopituitarism resulting in deficiency of pituitary hormones with deficiency of the growth hormone (100%) and gonadotropins (97.2%) being its ...
Atif Nawaz, MBBS, FCPS-I, FRCR-I +2 more
doaj +1 more source
Impact of Gene-Gender Effects of Adrenergic Polymorphisms on Hypothalamic-Pituitary-Adrenal Axis Activity in Depressed Patients [PDF]
, 2008 Objective: There is overwhelming evidence that activation of the hypothalamic-pituitary-adrenal (HPA) system plays a major role in depression and cardiovascular disease in genetically susceptible individuals.
Bondy, Brigitta +7 more
core +1 more source
The effect of acute heat exposure on rat pituitary corticotroph activation: the role of vasopressin.
Folia Histochemica et Cytobiologica, 2011 The increased ambient temperature affects the function of hypothalamic-pituitary-adrenal (HPA) axis. Since the correlation among vasopressin (VP), adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses to various stressors have been long ...
Sinisa Djurasevic +8 more
doaj +1 more source
PLoS ONE, 2022 Introduction Obesity is characterized by elevated lipids, insulin resistance and relative hypogonadotropic hypogonadism, reducing fertility and increasing risk of pregnancy complications and birth defects.
Rosemary McDonald +6 more
doaj +2 more sources
ZBTB20 is required for anterior pituitary development and lactotrope specification
Nature Communications, 2016 The pituitary is a complex structure with the anterior lobe containing five specialized cell types secreting different hormones. Here Cao et al. unravel a role for ZBTB20 in pituitary development and specifically in lactrotrope specification.
Dongmei Cao +16 more
doaj +1 more source
Successful twin pregnancy in panhypopituitarism
Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2015 Panhypopituitarism is characterized by inadequate or absent production of anterior pituitary hormones. This involves hypofunction of most of the major endocrine functions that affect fertility and reproduction.
R. D. Jeewantha +3 more
doaj +1 more source
Electrolyte Imbalance in Patients with Sheehan's Syndrome [PDF]
Endocrinology and Metabolism, 2015 BackgroundWe investigated the prevalence of electrolyte imbalance and the relationship between serum electrolyte and anterior pituitary hormone levels in patients with Sheehan's syndrome.MethodsIn a retrospective study, we investigated 78 patients with ...
Chur Hoan Lim +7 more
doaj +1 more source
TRH: Pathophysiologic and clinical implications [PDF]
, 1985 Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
Pickardt, C. R., Scriba, Peter Christian
core +1 more source
Panhypopituitarism Due to Hemochromatosis
Endocrinology Research and Practice, 2013 Hemochromatosis is an iron storage disease. Panhypopituitarism is a clinical condition in which the anterior pituitary hormones are deficient. Herein, we report a rare case of panhypopituitarism due to hemochromatosis.
Mesut Özkaya +3 more
doaj +1 more source