Results 31 to 40 of about 28,807 (265)

Investigation of the serum levels of anterior pituitary hormones in male children with autism

Molecular Autism, 2011
Background The neurobiological basis of autism remains poorly understood. The diagnosis of autism is based solely on behavioural characteristics because there are currently no reliable biological markers.
Iwata Keiko, Matsuzaki Hideo, Miyachi Taishi, Shimmura Chie, Suda Shiro, Tsuchiya Kenji J, Matsumoto Kaori, Suzuki Katsuaki, Iwata Yasuhide, Nakamura Kazuhiko, Tsujii Masatsugu, Sugiyama Toshirou, Sato Kohji, Mori Norio   +13 more
doaj   +1 more source

3D Atlas of the Pituitary Gland of the Model Fish Medaka (Oryzias latipes)

Frontiers in Endocrinology, 2021
In vertebrates, the anterior pituitary plays a crucial role in regulating several essential physiological processes via the secretion of at least seven peptide hormones by different endocrine cell types.
Muhammad Rahmad Royan, Khadeeja Siddique, Gergely Csucs, Maja A. Puchades, Rasoul Nourizadeh-Lillabadi, Jan G. Bjaalie, Christiaan V. Henkel, Finn-Arne Weltzien, Romain Fontaine   +8 more
doaj   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Late-onset hypophysitis after discontinuation of nivolumab treatment for advanced skin melanoma: a case report

BMC Endocrine Disorders, 2021
Background Nivolumab is an anti-programmed cell death protein 1 antibody, typically used as cancer immunotherapy agent. Despite multiple clinical benefits it might cause autoimmune-related side-effects, often involving the endocrine system.
Sofia Antoniou, Georgios Bazazo, Ludwig Röckl, Marios Papadakis, Christian Berg   +4 more
doaj   +1 more source

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

Advanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang, Lu Chen, Tiancheng Wu, Yating Li, Hui Wang   +4 more
wiley   +1 more source

Multihormonal pituitary adenoma concomitant with Pit-1 and Tpit lineage cells causing acromegaly associated with subclinical Cushing’s disease: a case report

BMC Endocrine Disorders, 2017
Background A functional pituitary adenoma can produce multiple anterior-pituitary hormones, such as growth hormone (GH) -producing adenomas (GHoma) with prolactin or thyrotropin stimulating hormone production in the same lineage. However, it is very rare
Tomoko Takiguchi, Hisashi Koide, Hidekazu Nagano, Akitoshi Nakayama, Masanori Fujimoto, Ai Tamura, Eri Komai, Akina Shiga, Takashi Kono, Seiichiro Higuchi, Ikki Sakuma, Naoko Hashimoto, Sawako Suzuki, Yui Miyabayashi, Norio Ishiwatari, Kentaro Horiguchi, Yukio Nakatani, Koutaro Yokote, Tomoaki Tanaka   +18 more
doaj   +1 more source

DIABETOGENIC ACTION OF PURIFIED ANTERIOR PITUITARY HORMONES

Endocrinology, 1949
This communication deals with the diabetogenic action of three of the anterior pituitary hormones, namely growth hormone, adrenocorticotrophic hormone (ACTH) and prolactin. Previous work has indicated that purified growth hormone is diabetogenic (Marx et al., 1943; Houssay, 1945).
Houssay, Bernardo A., Anderson, Evelyn
openaire   +3 more sources

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source