Results 51 to 60 of about 28,807 (265)

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

Analysis of patients with iatrogenic hypopituitarism after cranial irradiation

open access: yesРеальная клиническая практика: данные и доказательства
Hypopituitarianism is a chronic disease based on insufficient secretion of hormones in the anterior pituitary gland. Clinical manifestations of hypopituitarism are varied, often the lack of tropic hormones does not have pronounced symptoms, but the ...
Yu. Demchuk   +2 more
doaj   +1 more source

Evidence for adaptive explanations of semelparity in animals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher   +1 more
wiley   +1 more source

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino   +7 more
wiley   +1 more source

The effect of acute heat exposure on rat pituitary corticotroph activation: the role of vasopressin.

open access: yesFolia Histochemica et Cytobiologica, 2010
The increased ambient temperature affects the function of hypothalamic-pituitary-adrenal (HPA) axis. Since thecorrelation among vasopressin (VP), adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses to variousstressors have been long ...
Nebojsa Jasnic
doaj  

Anticipatory Stress in Medical Students Before Their First Cadaver Experience: A Physiological Component of Cadaver‐Based Anatomy Education

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Cadaver‐based anatomy education represents a unique biological and sensory experience that may elicit significant physiological responses. However, little is known about the anticipatory phase prior to initial exposure, particularly when evaluated using objective biomarkers.
María Resino‐Rocha   +5 more
wiley   +1 more source

Influence of Apricot Kernels on Blood Plasma Levels of Selected Anterior Pituitary Hormones in Male and Female Rabbits in vivo

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Amygdalin is represented in the family Rosacea more precisely in apricot kernels and almonds. There are a lot of components such as trace elements, vitamins, carbohydrates, organic acids, esters, phenols, terpenoids, except cyanogenic glycoside in the ...
Katarína Michalcová   +8 more
doaj  

Progress in the Pathogenesis, Diagnosis, and Treatment of TSH-Secreting Pituitary Neuroendocrine Tumor

open access: yesFrontiers in Endocrinology, 2020
TSH-secreting pituitary neuroendocrine tumor (PitNET) is one of the causes of central hyperthyroidism. The incidence of TSH PitNET is far lower than that of other PitNETs.
Peiqiong Luo   +4 more
doaj   +1 more source

Longitudinal Clinical Progression in X‐Linked Adrenoleukodystrophy: The AMNL Scoring System

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective The current clinical nomenclature for individuals with ABCD1 gene dysfunction is often uninformative. The disorder was initially described as a combination of adrenal insufficiency and leukodystrophy, leading to the widespread use of “X‐linked adrenoleukodystrophy” (ALD).
Eda G. Kabak   +7 more
wiley   +1 more source

Biography as the Missing Variable in Drug Development: A Case for Bio‐Biographical Mechanistic Profiling

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Most clinical trial failures reflect unmeasured biological heterogeneity. Biography — chronic stress, adversity, trauma, and social isolation—is a neglected source of that heterogeneity, operating through the same molecular pathways drugs engage.
Ralph I. Horwitz
wiley   +1 more source

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