Mathematical Modelling of Hypothalamus-Pituitary-Adrenal Axis Dynamics: A Review, a Novel Approach, and Future [PDF]
A novel mathematical model for the hypothalamic pituitary adrenal (HPA) axis is proposed to comprehend the oscillations observed in hormone concentration and potential dysfunction within the HPA axis in stressful situation. This model integrates impact of hippocampal receptors on the secretion of corticotropin-releasing hormone (CRH), an additional ...
arxiv
DynPeak : An algorithm for pulse detection and frequency analysis in hormonal time series [PDF]
The endocrine control of the reproductive function is often studied from the analysis of luteinizing hormone (LH) pulsatile secretion by the pituitary gland. Whereas measurements in the cavernous sinus cumulate anatomical and technical difficulties, LH levels can be easily assessed from jugular blood.
arxiv +1 more source
Diagnosis and Treatment of Pituitary Adenomas
Pituitary adenomas are among the most common primary intracranial tumours. They are predominantly benign and account for 10–15 % of all intracranial neoplasms. These tumours are divided into two subgroups: macroadenomas (> 1 cm) and microadenomas (<
O. A. Beylerli+3 more
doaj +1 more source
A unified model for the human response to lipopolysaccharide-induced inflammation [PDF]
This study develops a unified model predicting the whole-body response to endotoxin. We simulate dynamics using differential equations examining the response to a lipopolysaccharide (LPS) injection. The model tracks pro- and anti-inflammatory cytokines (TNF-$\alpha$, IL-6, IL-10), concentrations of corticotropin-releasing hormone (CRH ...
arxiv
Follicle-stimulating hormone receptor: Advances and remaining challenges [PDF]
Follicle-stimulating hormone (FSH) is produced in the pituitary and is essential for reproduction. It specifically binds to a membrane receptor (FSHR) expressed in somatic cells of the gonads. The FSH/FSHR system presents many peculiarities compared to classical G protein-coupled receptors (GPCRs).
arxiv +1 more source
Investigation of the serum levels of anterior pituitary hormones in male children with autism
BackgroundThe neurobiological basis of autism remains poorly understood. The diagnosis of autism is based solely on behavioural characteristics because there are currently no reliable biological markers.
Keiko Iwata+13 more
semanticscholar +1 more source
Basal Glucose Control in Type 1 Diabetes using Deep Reinforcement Learning: An In Silico Validation [PDF]
People with Type 1 diabetes (T1D) require regular exogenous infusion of insulin to maintain their blood glucose concentration in a therapeutically adequate target range. Although the artificial pancreas and continuous glucose monitoring have been proven to be effective in achieving closed-loop control, significant challenges still remain due to the ...
arxiv +1 more source
Background Though intensive genetic selection has led to extraordinary advances in growth rate and feed efficiency in production of meat-type chickens, endocrine processes controlling these traits are still poorly understood. The anterior pituitary gland
Laura E. Ellestad+7 more
doaj +1 more source
Induced spawning of the striped murrel Channa striatus using pituitary extracts, human chorionic gonadotropin, luteinizing hormone releasing hormone analogue, and ovaprim(r) [PDF]
Striated murrel Channa striatus were injected with natural hormones (pituitary extract and human chorionic gonadotropin) and synthetic hormones (luteinizing hormone releasing hormone analogue and ovaprim).
M.A. Haniffa+2 more
doaj +3 more sources
BackgroundThe new World Health Organization (WHO) classification system proposed a cell lineage-based classification scheme for pituitary adenomas in which transcription factors (TFs) play a major role as key classifiers.
Seung Woo Hong+14 more
doaj +1 more source