Results 41 to 50 of about 1,241,964 (276)

Stability analysis of a hypothalamic-pituitary-adrenal axis model with inclusion of glucocorticoid receptor and memory [PDF]

AIP Conference Proceedings 1798, 020111, 2017, 2016
This paper analyzes a four-dimensional model of the hypothalamic-pituitary-adrenal (HPA) axis that includes the influence of the glucocorticoid receptor in the pituitary. Due to the spatial separation between the hypothalamus, pituitary and adrenal glands, distributed time delays are introduced in the mathematical model.
arxiv   +1 more source

Pituitary Isograft Transplantation in Mice

Bio-Protocol, 2017
The mouse pituitary isograft is a technique developed to administer persistent hormone stimulation, thereby increasing cellular proliferation in the mammary tissue (Christov et al., 1993).
Chance Walker, Yan Hong, Frances Kittrell, Daniel Medina, David Edwards, Fariba Behbod   +5 more
doaj   +1 more source

Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics [PDF]

, 2016
The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are correlated with many stress-related diseases such as post-traumatic stress disorder (PTSD) and major depressive disorder.
arxiv   +1 more source

FSH and TSH in the Regulation of Bone Mass: The Pituitary/Immune/Bone Axis

Clinical and Developmental Immunology, 2013
Recent evidences have highlighted that the pituitary hormones have profound effects on bone, so that the pituitary-bone axis is now becoming an important issue in the skeletal biology.
Graziana Colaianni, Concetta Cuscito, Silvia Colucci   +2 more
doaj   +1 more source

Interrelationships between ovarian and pituitary hormones in ovulatory menstrual cycles across reproductive age.

Journal of Clinical Endocrinology and Metabolism, 2009
CONTEXT Ovarian hormones regulate pituitary gonadotropin secretion across the menstrual cycle via negative and positive feedback mechanisms. The contribution of individual hormones is complex and is a continuing area of research.
D. Robertson, G. Hale, D. Jolley, I. Fraser, C. Hughes, H. Burger   +5 more
semanticscholar   +1 more source

Advances in computational modeling approaches in pituitary gonadotropin signaling [PDF]

Expert Opinion on Drug Discovery, 1-15. (2018), 2018
Pituitary gonadotropins play an essential and pivotal role in the control of human and animal reproduction within the hypothalamic-pituitary-gonadal (HPG) axis. The computational modeling of pituitary gonadotropin signaling encompasses phenomena of different natures such as the dynamic encoding of gonadotropin secretion, and the intracellular cascades ...
arxiv   +1 more source

The Role of Adipokines in the Control of Pituitary Functions

Animals
The pituitary gland is a key endocrine gland in all classes of vertebrates, including mammals. The pituitary gland is an important component of hypothalamus–pituitary–target organ hormonal regulatory axes and forms a functional link between the nervous ...
Barbara Kaminska, Beata Kurowicka, Marta Kiezun, Kamil Dobrzyn, Katarzyna Kisielewska, Marlena Gudelska, Grzegorz Kopij, Karolina Szymanska, Barbara Zarzecka, Oguzhan Koker, Ewa Zaobidna, Nina Smolinska, Tadeusz Kaminski   +12 more
doaj   +1 more source

The effect of acute heat exposure on rat pituitary corticotroph activation: the role of vasopressin.

Folia Histochemica et Cytobiologica, 2011
The increased ambient temperature affects the function of hypothalamic-pituitary-adrenal (HPA) axis. Since the correlation among vasopressin (VP), adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses to various stressors have been long ...
Sinisa Djurasevic, Jelena Djordjevic, Igor Golic, Ksenija Velickovic, Aleksandra Korac, Nebojsa Jasnic, Iva Djordjevic, Predrag Vujovic, Gordana Cvijic   +8 more
doaj   +1 more source

Species-specific differences in follicular antral sizes result from diffusion-based limitations on the thickness of the granulosa cell layer [PDF]

, 2013
The size of mature oocytes is similar across mammalian species, yet the size of ovarian follicles increases with species size, with some ovarian follicles reaching diameters more than 1000-fold the size of the enclosed oocyte. Here we show that the different follicular sizes can be explained with diffusion-based limitations on the thickness of the ...
arxiv   +1 more source

Estrogenic Regulation of the GnRH Neuron

Frontiers in Endocrinology, 2012
Reproductive function is regulated by the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary and the steroid hormones from the gonads.
Sally eRadovick
doaj   +1 more source