Results 191 to 200 of about 235,360 (304)

Differential expression of cyclin D1 in pituitary neuroendocrine tumours: Relation to aggressive potential. [PDF]

Afr J Lab Med
Uchime KE, Awolola NA, Anunobi CC, Bankole OB, Banjo AA, Park SH.   +5 more
europepmc   +1 more source

ACTH-Producing Pituitary Gland Neoplasm [PDF]

, 2020
openaire   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Clinical and Genetic Spectrum of Large AIP Deletions. [PDF]

Hum Mutat
Kolnikaj TS, Ruka M, Xhumari A, Babameto-Laku A, Siolos A, Drakos PA, Magid K, Millner TO, Murray RD, Tzanela M, Miljić D, Ramaj A, Loughrey PB, Tigas S, Korbonits M.   +14 more
europepmc   +1 more source

Anterior Pituitary Gland Endocrine Neoplasm [PDF]

, 2020
openaire   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

MEN1 Deficiency Drives Lung Cancer Progression via Activation of MMP10‐Mediated Angiogenesis

Cancer Science, EarlyView.
MEN1 deficiency promotes JunD‐mediated upregulation of MMP10 expression, which cleaves pro‐HB‐EGF and activates endothelial EGFR. This triggers the PI3K/Akt and MEK/ERK signaling pathways, thereby driving angiogenesis and tumor progression. MMP10 inhibitor treatment blocks this cleavage, suppresses EGFR signaling, and thereby delays malignant ...
Chengyu Wei, Xiangyu Liu, Shimin Hu, Xiaodie Shen, Yingli Liu, Xinxin Qin, Ye Zhou, Jianqi Zheng, Bingke Tian, Jingfang Hong, Yongxia Song, Di Wang, Linlin Peng, Jinxia Ding, Fang Wang, Hui Zhang, Shihao Zhang, Huan Qiu   +17 more
wiley   +1 more source

Case Report: Pediatric ACTH-secreting pituitary adenoma presenting with hypertension and anuria. [PDF]

Front Endocrinol (Lausanne)
Li J, Xia W, Wu M.
europepmc   +1 more source

Prolactin-Producing Pituitary Gland Neoplasm [PDF]

, 2020
openaire   +1 more source

Psychological Stress Promotes Tumor Growth in Hepatocellular Carcinoma Models Through Myeloid Signaling

Cancer Science, EarlyView.
Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa, Takahiro Aoki, Tatsuya Kaneko, Hongxuan Wang, Daiki Shimizu, Daisuke Katsumi, Iori Kojima, Hidekazu Tanaka, Kiwamu Motoyoshi, Ko Ozaki, Katsuhiro Nishimura, Tomohisa Iinuma, Mariko Takami, Shinichiro Motohashi   +13 more
wiley   +1 more source