Results 201 to 210 of about 828,117 (319)

HMGA2 is a highly sensitive marker for DICER1‐related tumours

open access: yesHistopathology, EarlyView.
Aims DICER1 is a microRNA biogenesis enzyme that, when mutated, results in a rewiring of the transcriptome. Germline pathogenic variants (PVs) in DICER1 result in DICER1‐related tumour predisposition (DRTP) characterized by 30 or more different, generally rare, paediatric or adolescent‐onset tumours.
Paul S. Thorner   +5 more
wiley   +1 more source

Stathmin 1 across neuroendocrine neoplasms: biological, pathological and translational insights. [PDF]

open access: yesFront Endocrinol (Lausanne)
La Salvia A   +7 more
europepmc   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur   +6 more
wiley   +1 more source

Association between thyroid feedback quantile‐based index and the risk of in‐hospital amputation in patients with diabetic foot ulcer

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the relationship between the thyroid feedback quantile‐based index (TFQI) and the risk of amputation during hospitalization in patients with diabetic foot ulcers (DFU). Methods This single‐center retrospective study included 381 hospitalized patients with DFU and normal thyroid function.
Jiale Wang   +5 more
wiley   +1 more source

Modulation of sebocyte function in acne: A pathway‐inclusive review

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis   +3 more
wiley   +1 more source

The relationship between psychosocial risk and neurocognitive functioning early after childhood central nervous system tumour diagnosis

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Neurocognitive impairments are common in paediatric central nervous system (CNS) tumours and can relate to clinical and demographic factors. The impact of social or environmental factors, such as family psychosocial risk, is less well understood.
Jessica Beamish   +5 more
wiley   +1 more source

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