Cryptorchidism: Novel genetic insights into CCDC149 mutations
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du +8 more
wiley +1 more source
MRI features of craniopharyngiomas in different age groups and pathological subtypes. [PDF]
Wang W +11 more
europepmc +1 more source
Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto +12 more
wiley +1 more source
Predictive capacity of mismatch repair status in the use of immune checkpoint inhibitors for the treatment of aggressive pituitary tumors and pituitary carcinomas: An illustrative case report and literature review. [PDF]
Ivey N +18 more
europepmc +1 more source
Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley +1 more source
Nivolumab-associated hypopituitarism in a 61-year-old woman with metastatic triple-negative breast. [PDF]
Lomidze K +4 more
europepmc +1 more source
Aging‐associated upregulation of NPY1R drives p‐CREB activation, triggering inflammation, mitochondrial dysfunction, and extracellular matrix imbalance to promote ovarian senescence. Pharmacological inhibition of NPY1R with BIBO 3304 restores ovarian homeostasis, highlighting a therapeutic strategy for reproductive aging. ABSTRACT Ovarian senescence is
Junnan Fang +15 more
wiley +1 more source
A rare case of dual hormone-secreting pulmonary neuroendocrine tumor causing concurrent Cushing syndrome and acromegaly. [PDF]
Sudhakar D +4 more
europepmc +1 more source
Recurrent pituitary apoplexy: experience from a national registry and review of the literature. [PDF]
Biagetti B +9 more
europepmc +1 more source

