Results 231 to 240 of about 514,858 (318)

New Neoplasm During GH Replacement in Adults With Pituitary Deficiency Following Malignancy: A KIMS Analysis [PDF]

, 2017
Katarzyna Krzyzanowska-Mittermayer, Anders Mattsson, Dominique Maiter, Ulla Feldt‐Rasmussen, Cecilia Camacho‐Hübner, Anton Luger, Roger Abs   +6 more
openalex   +1 more source

Genocopy of EVI1‐AML with paraneoplastic diabetes insipidus: PRDM16 overexpression by t(1;2)(p36;p21) and enhancer hijacking

British Journal of Haematology, EarlyView.
Summary Diabetes insipidus (DI) in patients with acute myeloid leukaemia (AML) and chromosome 3q alterations (EVI1/PRDM3/MECOM overexpression) constitutes a poorly understood paraneoplasia. A 44‐year‐old patient presented with clinical and morphological features of this syndrome but, surprisingly, disclosed the rare translocation t(1;2)(p36;p21), with ...
Julian List, Etienne Sollier, Fiona Brown‐Burke, Katherine Kelly, Dietmar Pfeifer, Valeria Shlyakhto, Kristina Maas‐Bauer, Milena Pantic, Christoph Plass, Michael Lübbert   +9 more
wiley   +1 more source

A blood-based liquid biopsy analyzing soluble immune checkpoints and cytokines identifies distinct neuroendocrine tumors. [PDF]

J Exp Clin Cancer Res
Mata-Martínez P, Celada L, Cueto FJ, Sáenz de Santa María G, Fernández J, Terrón-Arcos V, Valdés N, Moreira VG, Del Toro MIE, López-Collazo E, Chiara MD, Del Fresno C.   +11 more
europepmc   +1 more source

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

British Journal of Pharmacology, EarlyView.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf, Laura J. Humphrys, Sandra Berndt, Antonella Di Pizio, Juliane Lehmann, Ines Liebscher, Alessandro Nicoli, Masha Y. Niv, Lior Peri, Hannes Schihada, Gunnar Schulte   +10 more
wiley   +1 more source

Heterozygous <i>Men1</i>(+/T) Knockout Mice Do Not Develop Bronchopulmonary Neuroendocrine Hyperplasia or Neoplasia but Bronchial Adenocarcinoma. [PDF]

Adv Respir Med
Albers MB, Fink L, Manoharan J, Lopez CL, Bollmann C, Bartsch DK.   +5 more
europepmc   +1 more source

Metastatic pituitary neuroendocrine neoplasms: A case report of a malignant prolactinoma

Inês Manique, Sara Amaral, Teresa Rego, Andreia Coelho, Andreia Ponte, Margarida Brito, Ana Palha, Luísa Cortez, Dalila Forte, Amets Sagarribay, Luís Cerqueira, Carlos Pontinha, Manuela Mafra, José Silva‐Nunes   +13 more
openalex   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Second Primary Tumors After Primary Brain Tumors and Vice Versa: A Single-Center, Retrospective Study. [PDF]

Brain Tumor Res Treat
Angez M, Tariq R, Zafar A, Ahmed AA, Hameed AN, Waqar U, Enam SA.   +6 more
europepmc   +1 more source

High-Grade Progression, Sarcomatous Transformation, and/or Metastasis of Pituitary Neuroendocrine Neoplasms (PitNENs): The UCSF Experience [PDF]

Merryl Terry, Minh Nguyen, Vivian Tang, Ekin Güney, Krishna Bharani, Sonika Dahiya, Ondrej Choutka, Ewa Borys, Gerald F. Reis, Lewis S. Blevins, Manish K. Aghi, Sandeep Kunwar, John DeGroot, David R. Raleigh, Melike Pekmezci, Andrew W. Bollen, Soonmee Cha, Nancy M. Joseph, Arie Perry   +18 more
openalex   +1 more source

Dimerisation of the VIP receptor VIPR2 is essential to its binding VIP and Gαi proteins, and to its functions in breast cancer cells

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Several G protein‐coupled receptors (GPCRs) are known to homodimerise. Dimeric GPCRs may have different properties from their monomers, but the molecular basis and functional significance of GPCR dimerisation remain largely unknown.
Satoshi Asano, Kairi Ozasa, Teru Uehara, Rei Yokoyama, Takanobu Nakazawa, Souichi Yanamoto, Yukio Ago   +6 more
wiley   +1 more source