Results 41 to 50 of about 1,442,730 (143)

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

Mutations in the Human ROBO1 Gene in Pituitary Stalk Interruption Syndrome

, 2017
International audiencePituitary stalk interruption syndrome (PSIS) is characterized by a thin or absent pituitary stalk usually in association with an ectopic posterior pituitary and hypoplasia/aplasia of the anterior pituitary.
Raja Brauner, Bignon-Topalovic, Joelle, Anu Bashamboo, Ken McElreavey, Moussi, Nasser, Mcelreavey, Ken, Joelle Bignon-Topalovic, Nasser Moussi, Bashamboo, Anu, Brauner, Raja   +9 more
core   +1 more source

Pituitary stalk interruption syndrome presenting as short stature: a case report [PDF]

, 2014
Introduction: Pituitary stalk interruption syndrome is a rare congenital abnormality of the pituitary that is responsible for anterior pituitary deficiency.
Ram, Nanik, Ali, Syed Ahsan, Hussain, Syed Zubair, Nanik Ram, Syed Zubair Hussain, Syed Ahsan Ali   +5 more
core   +2 more sources

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

iMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang, Jinfei Liu, Qiangsheng Wang, Lei Fan, Ziang Li, Xuexin Yu, Yonghao Chen, Xiaofan Lu, Guiyi Liao, Jialin Meng, Yu Guan   +10 more
wiley   +1 more source

Ectopic Posterior Pituitary, Polydactyly, Midfacial Hypoplasia and Multiple Pituitary Hormone Deficiency due to a Novel Heterozygous IVS11-2A>C(c.1957-2A>C) Mutation in the GLI2 Gene

JCRPE, 2020
A novel heterozygous IVS11-2A>C(c.1957-2A>C) mutation in the GLI2 gene is reported. There was an extremely distinct phenotypical expression in two siblings and their father.
Meliha Demiral, Hüseyin Demirbilek, Edip Unal, Ceren Damla Durmaz, Serdar Ceylaner, Mehmet Nuri Özbek   +5 more
doaj   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Bibliometric Analysis of Research on Pituitary Adenomas: Recent Progress in Pathogenesis and Clinical Management

Medicine Advances, EarlyView.
A bibliometric analysis of 15,418 publications mapped global research on pituitary adenomas and identified 6 major research themes. Keyword trends highlighted the growing prominence of artificial intelligence‐related research. ABSTRACT Background Pituitary adenomas (PAs) comprise most of the tumors that originate from the sellar region.
Zhengyang Shen, Kan Deng, Lin Lu, Jifang Liu, Zhang Ye, Yi Zhang, Yong Yao   +6 more
wiley   +1 more source

Digenic Inheritance of PROKR2 and WDR11 Mutations in Pituitary Stalk Interruption Syndrome [PDF]

, 2017
Context: Pituitary stalk interruption syndrome (PSIS, ORPHA95496) is a congenital defect of the pituitary gland characterized by the triad of a very thin/interrupted pituitary stalk, an ectopic (or absent) posterior pituitary gland, and hypoplasia or ...
Kim, YJ, Yeon Joo Kim, Michael A. Levine, Ji Young Lee, Kim, S-H, Rapaport, R, Li, D, Shana E. McCormack, Levine, MA, Dong Li, Lee, JY, Robert Rapaport, McCormack, SE, Soo-Hyun Kim   +13 more
core   +1 more source

Impact of sleep insufficiency and recovery on cancer development

Sleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Whole-Exome Sequencing Identifies Homozygous GPR161 Mutation in a Family with Pituitary Stalk Interruption Syndrome [PDF]

, 2015
Erdin, Serkan/0000-0001-6587-2625; Yaykasli, Kursat/0000-0001-7550-6370; Yaykasli, Emine/0000-0001-6471-0106; Gambin, Tomasz/0000-0002-0941-4571WOS: 000353281300033PubMed: 25322266Context: Pituitary stalk interruption syndrome (PSIS) is a rare ...
Yaykaşlı, Kürşat Oğuz, Karaca, Ender, Bayram, Yavuz, Charng, Wu-Lin, Lupski, James R., Büyükkaya, Ramazan, Pehlivan, Davut, Tomasz Gambin, Semih Bolu, Ilknur Arslanoglu, Ender Karaca, Mehmed M. Atik, Donna M. Muzny, Yavuz Bayram, Davut Pehlivan, Wu-Lin Charng, Marjorie Withers, Ayla Buyukkaya, Ramazan Buyukkaya, Serkan Erdin, James R. Lupski, Kursat O. Yaykasli, Richard A. Gibbs, Emine Yaykasli, Shalini N. Jhangiani   +24 more
core   +1 more source