Results 51 to 60 of about 1,442,730 (143)

Seasonal variation in faecal glucocorticoid metabolite concentrations of two dominant southern African murids (Lemniscomys rosalia and Mastomys coucha) across variously transformed landscapes

Wildlife Biology, EarlyView.
Global landscape transformations are a result of a growing human population and the subsequent increased use of natural habitats. Local species extinctions across various transformed landscapes emphasise the importance of monitoring wildlife responses to anthropogenic activities.
Mmatsawela Ramahlo, Michael J. Somers, Andre Ganswindt   +2 more
wiley   +1 more source

Diagnóstico tardío de síndrome de interrupción del tallo hipofisario

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2017
El síndrome de interrupción del tallo hipofisario (PSIS, por sus siglas en inglés) es una anomalía congénita de probable origen genético causante de hipopituitarismo, que se caracteriza por hipoplasia de la adenohipófisis, neurohipófisis ectópica e ...
Vanessa Garzón Graciano, Santiago González Narvaez, Jhon Alexander Alzate Piedrahita, Víctor Hugo Ruiz Granada, Santiago Vallejo González   +4 more
doaj   +1 more source

Fecal Glucocorticoid and Androgen Metabolites in Eastern Grey Kangaroos (Macropus giganteus) Following Environmental Relocation

Zoo Biology, EarlyView.
Fecal glucocorticoid (GCM) and androgen metabolite (AM) concentrations were monitored for 3 months following the relocation of three eastern gray kangaroos (Macropus giganteus) between zoological facilities. Both metabolites showed high concentrations during the early postrelocation period, followed by a rapid decline and stabilization, suggesting ...
Laura Menchetti, Rupert Palme, Livio Galosi, Giacomo Rossi, Elena Fraticelli, Gaia Andrea Bevinetto, Gioia Gaiot, Renato Piccinini, Raffaello Gambi, Matteo Cerquetella   +9 more
wiley   +1 more source

PROKR2 Variants in Multiple Hypopituitarism with Pituitary Stalk Interruption.

, 2012
International audienceContext:Pituitary stalk interruption represents a frequent feature of congenital hypopituitarism, but only rare cases have been assigned to a known genetic cause.Objective:Using a candidate gene approach, we tested several genes as ...
Saveanu, Alexandru, Rondard, Philippe, Simonin, Gilbert, Martinez-Barbera, Juan Pedro, Guiochon-Mantel, Anne, Bouligand, Jérome, Guedj, Anne-Marie, Monnier, Carine, Brue, Thierry, Barlier, Anne,, Barlier, Anne, A., Lecomte, Pierre, Jayakody, Sujatha A, Reynaud, Rachel   +13 more
core   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Diagnosis and Management of Central Congenital Hypothyroidism

Frontiers in Endocrinology, 2021
Central congenital hypothyroidism (CH) is defined as thyroid hormone (TH) deficiency at birth due to insufficient stimulation by the pituitary of the thyroid gland. The incidence of central CH is currently estimated at around 1:13,000.
Peter Lauffer, Nitash Zwaveling-Soonawala, Jolanda C. Naafs, Anita Boelen, A. S. Paul van Trotsenburg   +4 more
doaj   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

A case report of Culler-Jones syndrome with deafness carrying a novel mutation in GLI2 gene

BMC Pediatrics
Background Culler-Jones syndrome (CJS)(OMIM: 615849) is a rare genetic disorder characterized by multiple anterior pituitary hormone deficiencies and variable polydactyly, caused by mutations in the GLI2 gene (OMIM: 165230).
Xuewen Yuan, Shanshan Chu, Wei Gu
doaj   +1 more source

Puberty and Inhibin B in 35 Adolescents With Pituitary Stalk Interruption Syndrome

Frontiers in Pediatrics, 2020
Background: In patients with pituitary stalk interruption syndrome (PSIS), long-term follow-up is necessary to address their gonadotrophic status. The objectives of this study were (1) to describe pubertal features of and (2) to assess the ability of ...
Victoria Corvest, Pierre Lemaire, Sylvie Brailly-Tabard, Raja Brauner   +3 more
doaj   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source