Results 1 to 10 of about 87,781 (261)

Automatic Detection for Acromegaly Using Hand Photographs: A Deep-Learning Approach

IEEE Access, 2021
Machine learning assisted diagnosis of acromegaly from facial photographs has been proved feasible in recent years. According to our previous research, facial and limb changes exist in patients with acromegaly at early stage.
Chengbin Duan, Wenli Chen, Shun Yao, Zhigang Mao, Zongming Wang, Bin Hu, Haosen Jiao, Dimin Zhu, Yonghong Zhu, Haijun Wang   +9 more
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Prediction of the Recurrence of Non-Functioning Pituitary Adenomas Using Preoperative Supra-Intra Sellar Volume and Tumor-Carotid Distance

Frontiers in Endocrinology, 2021
BackgroundCurrently, it is difficult to estimate the possibility of recurrence of nonfunctioning pituitary adenomas (NFPAs). Markers such as Ki-67 or transcription factors rely on postoperative pathology, while few indices can be used for preoperative ...
Wenli Chen, Mengqi Wang, Chengbin Duan, Shun Yao, Haosen Jiao, Zongming Wang, Bin Hu, Zhigang Mao, Yonghong Zhu, Haijun Wang   +9 more
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Genomic landscape of gliosarcoma: distinguishing features and targetable alterations

Scientific Reports, 2021
Gliosarcoma is an aggressive brain tumor with histologic features of glioblastoma (GBM) and soft tissue sarcoma. Despite its poor prognosis, its rarity has precluded analysis of its underlying biology.
Mark M. Zaki, Leila A. Mashouf, Eleanor Woodward, Pinky Langat, Saksham Gupta, Ian F. Dunn, Patrick Y. Wen, Brian V. Nahed, Wenya Linda Bi   +8 more
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Sub-macroscopic skin presentation of acromegaly and effect of pituitary tumor surgery: A study using dermatoscopy and ultra-high-frequency ultrasound

Frontiers in Endocrinology, 2023
ObjectiveExcessive growth hormone and insulin-like growth factor 1 contribute to cutaneous changes in acromegaly. We investigated the sub-macroscopic skin manifestation of acromegaly patients and explored its reversibility upon hormone reduction after ...
Xiaopeng Guo, Yukun Wang, Yong Yao, Xinjie Bao, Lian Duan, Huijuan Zhu, Bing Xing, Jie Liu   +7 more
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Change in the pituitary stalk deviation angle after transsphenoidal surgery can predict the development of diabetes insipidus for pituitary adenomas

Endocrine Connections, 2022
Purpose: We aimed to assess the factors influencing the development of d iabetes insipidus after transsphenoidal surgery for pituitary adenomas. Methods: A retrospective analysis was conducted on the clinical data of patients with pituitary adenomas ...
Liang Xue, Jianwu Wu, Jie Chen, Yongkai Yang   +3 more
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Multiparametric MRI Features Predict the SYP Gene Expression in Low-Grade Glioma Patients: A Machine Learning-Based Radiomics Analysis

Frontiers in Oncology, 2021
PurposeSynaptophysin (SYP) gene expression levels correlate with the survival rate of glioma patients. This study aimed to explore the feasibility of applying a multiparametric magnetic resonance imaging (MRI) radiomics model composed of a convolutional ...
Zheng Xiao, Shun Yao, Shun Yao, Zong-ming Wang, Di-min Zhu, Ya-nan Bie, Shi-zhong Zhang, Wen-li Chen   +7 more
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Translational Windows in Chordoma: A Target Appraisal

Frontiers in Neurology, 2020
Chordomas are rare tumors that are notoriously refractory to chemotherapy and radiotherapy when radical surgical resection is not achieved or upon recurrence after maximally aggressive treatment.
Samantha E. Hoffman, Sally A. Al Abdulmohsen, Saksham Gupta, Blake M. Hauser, David M. Meredith, Ian F. Dunn, Wenya Linda Bi   +6 more
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Endoscopy in pituitary diseases

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
The etiology pattern of pituitary diseases is diverse and complex, including pituitary adenoma, Rathke cleft cyst (RCC), pituitary apoplexy, craniopharyngioma, etc.
ZHU Jian⁃yu, WANG Zhi⁃cheng, YAO Yong   +2 more
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Identification and Preservation of Pituitary Gland in Pituitary Surgery [PDF]

Al-Azhar International Medical Journal, 2022
Background: Suppressing hormone hyper-secretion, lowering tumour mass, preserving normal pituitary function, minimizing long-term effects from excess hormone production, and preventing tumour recurrence are all aims of pituitary tumour treatment ...
Islam Al Aghory, Abd Elkafy Sharafuddin, Mahamad Alhamshary   +2 more
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Depression and Impulsivity Self-Assessment Tools to Identify Dopamine Agonist Side Effects in Patients With Pituitary Adenomas

Frontiers in Endocrinology, 2020
Background: Dopamine agonists (DA) are the first line therapy for prolactinoma and symptomatic hyperprolactinemia; use as an adjuvant treatment for acromegaly and Cushing's disease is rare.
José Miguel Hinojosa-Amaya, José Miguel Hinojosa-Amaya, Nathaniel Johnson, Christina González-Torres, Elena V. Varlamov, Christine G. Yedinak, Shirley McCartney, Maria Fleseriu   +7 more
doaj   +1 more source