Results 11 to 20 of about 3,152,858 (268)

Glymphatic transport is reduced in rats with spontaneous pituitary tumor [PDF]

open access: yesFrontiers in Medicine, 2023
Background and objectivePituitary tumor in patients induces adverse alterations in the brain, accompanied by cognitive deficits. Dysfunction of glymphatic waste clearance results in accumulation of neurotoxic products within the brain, leading to ...
Lian Li   +10 more
doaj   +2 more sources

Transcranial Sonography in the Diagnosis of Pituitary Tumor—A Direct Comparison With MRI [PDF]

open access: yesFrontiers in Endocrinology, 2021
BackgroundTranscranial sonography (TCS) is a convenient tool for detecting certain brain diseases, such as brain tumors. Few studies have reported on the use of TCS in the area of Sella turcica.
Lei He   +6 more
doaj   +2 more sources

A Deep Learning Approach for Brain Tumor Classification and Segmentation Using a Multiscale Convolutional Neural Network [PDF]

open access: yesHealthcare 2021, 9, 153, 2021
In this paper, we present a fully automatic brain tumor segmentation and classification model using a Deep Convolutional Neural Network that includes a multiscale approach. One of the differences of our proposal with respect to previous works is that input images are processed in three spatial scales along different processing pathways.
F. Pernas   +3 more
arxiv   +3 more sources

Automatic Detection for Acromegaly Using Hand Photographs: A Deep-Learning Approach

open access: yesIEEE Access, 2021
Machine learning assisted diagnosis of acromegaly from facial photographs has been proved feasible in recent years. According to our previous research, facial and limb changes exist in patients with acromegaly at early stage.
Chengbin Duan   +9 more
doaj   +1 more source

Clinical Efficacy of Temozolomide and Its Predictors in Aggressive Pituitary Tumors and Pituitary Carcinomas: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Neurology, 2021
Background: A growing number of evidences suggest that TMZ applications can generate impressive benefits for APT and PC patients. However, the definite role of TMZ for individuals remains unclarified due to the variation between studies.
Mei Luo   +9 more
doaj   +1 more source

Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells

open access: yesScientific Reports, 2023
Raising reactive oxygen species (ROS) levels in cancer cells to cause macromolecular damage and cell death is a promising anticancer treatment strategy. Observations that electromagnetic fields (EMF) elevate intracellular ROS and cause cancer cell death,
Shashank Hambarde   +4 more
doaj   +1 more source

Hydroxychloroquine overcomes cabergoline resistance in a patient with Lactotroph Pituitary neuroendocrine tumor: a case report

open access: yesFrontiers in Endocrinology, 2022
ObjectiveA 22-year-old man complaining erectile dysfunction underwent transsphenoidal surgery for a 2.7 cm sellar mass with total resection and was confirmed at pathology to have a lactotroph pituitary neuroendocrine tumor (PiNET).
Shaojian Lin   +3 more
doaj   +1 more source

Novel somatic variants involved in biochemical activity of pure growth hormone-secreting pituitary adenoma without GNAS variant

open access: yesScientific Reports, 2021
We aimed to identify somatic genetic alterations in pure growth hormone (GH)-secreting pituitary adenomas without GNAS variants. Patients with GH-secreting pituitary adenoma who underwent transsphenoidal adenomectomy at Severance Hospital, Yonsei ...
Cheol Ryong Ku   +8 more
doaj   +1 more source

Prevalence and clinical characteristics of Crooke’s cell adenomas in 101 patients with T-PIT-positive pituitary adenomas: Case series and literature review

open access: yesFrontiers in Endocrinology, 2022
PurposeWe aimed to perform a retrospective analysis of a rare subtype of corticotroph adenoma, Crooke’s cell adenoma, to better understand its clinical features.MethodsWe collected T-PIT-positive pituitary adenomas and screened Crooke’s cell adenomas ...
Dimin Zhu   +7 more
doaj   +1 more source

Association of Pathology Markers with Somatostatin Analogue Responsiveness in Acromegaly

open access: yesInternational Journal of Endocrinology, 2022
Background. Somatotroph adenomas (SAs) exhibit a variable responsiveness to somatostatin analogue (SS-a) treatment, a process that is not well understood.
George Kontogeorgos   +7 more
doaj   +1 more source

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