Results 11 to 20 of about 105,804 (267)
Frontiers in Oncology, 2021 Alternating electric field therapy has been approved for glioblastoma (GBM). We have preclinical evidence for anticancer effects in GBM cell cultures and mouse xenografts with an oscillating magnetic field (OMF) generating device.
David S. Baskin +9 more
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Frontiers in Oncology, 2021 BackgroundThe new World Health Organization (WHO) classification system proposed a cell lineage-based classification scheme for pituitary adenomas in which transcription factors (TFs) play a major role as key classifiers.
Seung Woo Hong +14 more
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Aggressive Pituitary Tumors [PDF]
Neuroendocrinology, 2015 Pituitary adenomas are common intracranial tumors that are mainly considered as benign. Rarely, these tumors can exhibit an aggressive behavior, characterized by gross invasion of the surrounding tissues, resistance to conventional treatment leading to early and frequent recurrences.
Chatzellis, E. +3 more
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Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing’s Disease
Frontiers in Endocrinology, 2021 PurposeTo investigate the role of heat-shock protein Hsp90 in adrenocorticotropic hormone (ACTH)-secreting cells, and to explore the potential clinical application of an inhibitor of Hsp90, 17-N-allylamino-17-demethoxygeldanamycin(17-AAG) in ...
Yue Shen +17 more
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Frontiers in Oncology, 2021 Electromagnetic fields (EMF) raise intracellular levels of reactive oxygen species (ROS) that can be toxic to cancer cells. Because weak magnetic fields influence spin state pairing in redox-active radical electron pairs, we hypothesize that they disrupt
Martyn A. Sharpe +17 more
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Evolution of Minimally Invasive Approaches to the Sella and Parasellar Region
International Archives of Otorhinolaryngology, 2014 Introduction Given advancements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques, and anatomical understanding, the endonasal endoscopic approach has rapidly evolved into a widely utilized technique for ...
Robert G. Louis +4 more
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How to Classify and Define Pituitary Tumors: Recent Advances and Current Controversies
Frontiers in Endocrinology, 2021 Pituitary tumors are very complex and heterogeneous and have a very wide range of proliferative and aggressive behaviors, and how to define and classify these tumors remains controversial.
Congxin Dai +8 more
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Endocrinology and Metabolism Clinics of North America, 2015 Pituitary tumors are commonly encountered intracranial neoplasms that are invariably benign. Classic oncogene mutations are not encountered in these tumors, and disrupted cell cycle control and growth factor signaling likely contribute to pathogenesis and natural history.
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Pituitary tumor apoplexy [PDF]
Arquivos de Neuro-Psiquiatria, 2009 Pituitary tumor apoplexy is a medical emergency due to acute infarction or hemorrhage in the pituitary gland. In this review, the authors discuss the sellar anatomy, the pituitary gland and adenomas' vascularization and the general aspects of the syndrome such as its ethiopatogenesis, predisposing factors, clinical features, treatment and prognosis.
Chang, Claudia V. +4 more
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