Results 41 to 50 of about 3,259,919 (360)
Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors
Oncogene, 2019 The molecular mechanisms leading to aryl hydrocarbon receptor interacting protein (AIP) mutation-induced aggressive, young-onset growth hormone-secreting pituitary tumors are not fully understood.
Sayka Barry +15 more
semanticscholar +1 more source
Corticotropinoma as a Component of Carney Complex. [PDF]
, 2017 Known germline gene abnormalities cause one-fifth of the pituitary adenomas in children and adolescents, but, in contrast with other pituitary tumor types, the genetic causes of corticotropinomas are largely unknown.
Chittiboina, Prashant +11 more
core +2 more sources
BMC Pharmacology and Toxicology, 2017 Background Many patients with acromegaly require medical treatment that includes somatostatin analogs (SSAs). Long-acting SSA formulations are widely used, due in part to increased patient convenience and increased treatment adherence vs daily ...
Michelle H. Gurel +4 more
doaj +1 more source
Frontiers in Neurology, 2020 Introduction: The recent publication of a trial failed to prove the efficacy of minimally invasive surgery (MIS) in patients with intracerebral hemorrhage.
Xiang Zhou +5 more
doaj +1 more source
Thyroxine-binding globulin: investigation of microheterogeneity [PDF]
, 1981 Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland +4 more
core +1 more source
Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours
Nature Communications, 2018 LncRNA H19 has been shown to be aberrantly expressed in different cancers. Here, the authors show that H19 lncRNA is downregulated in pituitary adenomas and H19 is able to impede pituitary tumorigenesis via disruption of 4E-BPB1 and Raptor interaction to
Ze Rui Wu +18 more
doaj +1 more source
Interdisciplinary Neurosurgery, 2020 Background: Neuro-endocrine dysfunction such as electrolyte imbalance and hypopituitarism are among the most frequent surgical complications following pituitary macroadenoma resection.
Solon Schur +3 more
doaj +1 more source
Transcranial Sonography in the Diagnosis of Pituitary Tumor—A Direct Comparison With MRI
Frontiers in Endocrinology, 2021 BackgroundTranscranial sonography (TCS) is a convenient tool for detecting certain brain diseases, such as brain tumors. Few studies have reported on the use of TCS in the area of Sella turcica.
Lei He +6 more
doaj +1 more source
Gene Expression and the Physiological Role of Transforming Growth Factor-α in the Mouse Pituitary [PDF]
, 2003 Transforming growth factor-alpha (TGF-alpha), a member of the epidermal growth factor (EGF) family, is produced within the mouse anterior pituitaries. However, the cell types of TGF-alpha-expressing cells and the physiological roles of TGF-a within mouse
Kakeya, Tomoshi +5 more
core +1 more source
Arthritis Care &Research, EarlyView.As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source