Results 41 to 50 of about 3,152,858 (268)
BMC Endocrine Disorders, 2021 Background Pituitary adenomas are benign brain tumors that cause considerable morbidity and neurological symptoms. SOX9 as a regulatory transcriptional mediator affects normal and tumor cell growth with an undefined role in pituitary adenomas ...
Farzad Izak Shirian +8 more
doaj +1 more source
Endocrine-Related Cancer, 2017 The classification of neoplasms of adenohypophysial cells is misleading because of the simplistic distinction between adenoma and carcinoma, based solely on metastatic spread and the poor reproducibility and predictive value of the definition of atypical
Sylvia L. Asa +24 more
semanticscholar +1 more source
Does an Analysis of the Pulsatile Secretion Pattern of Adrenocorticotropin and Cortisol Predict the Result of Transsphenoidal Surgery in Cushing’s Disease. [PDF]
, 1993 The endocrinological, surgical, and histological findings of patients with ACTH-dependent Cushing's disease were correlated with the pulsatile secretion pattern of ACTH and cortisol and the outcome after transsphenoidal pituitary surgery.
Brabant, Georg +5 more
core +1 more source
Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours
Nature Communications, 2018 LncRNA H19 has been shown to be aberrantly expressed in different cancers. Here, the authors show that H19 lncRNA is downregulated in pituitary adenomas and H19 is able to impede pituitary tumorigenesis via disruption of 4E-BPB1 and Raptor interaction to
Ze Rui Wu +18 more
doaj +1 more source
BMC Pharmacology and Toxicology, 2017 Background Many patients with acromegaly require medical treatment that includes somatostatin analogs (SSAs). Long-acting SSA formulations are widely used, due in part to increased patient convenience and increased treatment adherence vs daily ...
Michelle H. Gurel +4 more
doaj +1 more source
Frontiers in Neurology, 2020 Introduction: The recent publication of a trial failed to prove the efficacy of minimally invasive surgery (MIS) in patients with intracerebral hemorrhage.
Xiang Zhou +5 more
doaj +1 more source
The pituitary TGFb1 system as a novel target for the treatment of resistant prolactinomas [PDF]
, 2016 Prolactinomas are the most frequently observed pituitary adenomas and most of themrespond well to conventional treatment with dopamine agonists (DAs).
Camilletti, María Andrea +3 more
core +2 more sources
Deprenyl, an old drug with new anticancer potential: Mini review [PDF]
arXiv, 2021 The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv
Clinical Case Reports, 2023 Key Clinical Message To investigate the blood supply characteristics and surgical significance of pituitary neuroendocrine tumors with vascular flow void signal in tumors.
Jiansheng Zhong, Jun Li, Shousen Wang
doaj +1 more source
Examining the behaviour of state-of-the-art convolutional neural networks for brain tumor detection with and without transfer learning [PDF]
arXiv, 2022 Distinguishing normal from malignant and determining the tumor type are critical components of brain tumor diagnosis. Two different kinds of dataset are investigated using state-of-the-art CNN models in this research work. One dataset(binary) has images of normal and tumor types, while another(multi-class) provides all images of tumors classified as ...
arxiv