Results 1 to 10 of about 109,445 (264)
Endocrinology and Metabolism Clinics of North America, 2015 Pituitary tumors are commonly encountered intracranial neoplasms that are invariably benign. Classic oncogene mutations are not encountered in these tumors, and disrupted cell cycle control and growth factor signaling likely contribute to pathogenesis and natural history.
Шломо Мелмед
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Genetically engineered mouse models of pituitary tumors [PDF]
Frontiers in Oncology, 2014 Animal models constitute valuable tools for investigating the pathogenesis of cancer as well as for preclinical testing of novel therapeutics approaches.
David A Cano +4 more
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Orthotopic pituitary tumors generated by stereotaxic GC cell injection in immunocompetent rats [PDF]
Acta Neuropathologica CommunicationsInnovative treatment strategies for pituitary tumors are necessary to limit the disease burden and to improve survival in cases of carcinomas. The paucity and inaccuracy of available preclinical models substantially hamper pituitary research and drug ...
Etienne Lefevre +10 more
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PIT-1/SF-1-positive pituitary tumors in patients with acromegaly: transcriptomic perspective [PDF]
Acta Neuropathologica CommunicationsNeuroendocrine pituitary tumors (PitNETs) are classified based on clinical manifestation and expression of pituitary cell lineage-specific transcription factors (TFs) and hormones.
Julia Rymuza, Qilin Zhang, Mateusz Bujko
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Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors
Frontiers in Endocrinology, 2022 Since Costello et al. proposed the concept of pseudocapsule of pituitary neuroendocrine tumors (PitNETs) in 1936, many studies have been published on its occurrence, development process, histopathology, and morphology.
Xiao Bin Wang +6 more
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Sprouting Angiogenesis in Human Pituitary Adenomas
Frontiers in Oncology, 2022 IntroductionAngiogenesis in pituitary tumors is not fully understood, and a better understanding could help inform new pharmacologic therapies, particularly for aggressive pituitary tumors.Materials and Methods219 human pituitary tumors and 12 normal ...
Jie Zhou +15 more
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Costs and Its Determinants in Pituitary Tumour Surgery
Frontiers in Endocrinology, 2022 PurposeValue-based healthcare (VBHC) provides a framework to improve care by improving patient outcomes and reducing healthcare costs. To support value-based decision making in clinical practice we evaluated healthcare costs and cost drivers in ...
Alies J. Dekkers +14 more
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How to Classify and Define Pituitary Tumors: Recent Advances and Current Controversies
Frontiers in Endocrinology, 2021 Pituitary tumors are very complex and heterogeneous and have a very wide range of proliferative and aggressive behaviors, and how to define and classify these tumors remains controversial.
Congxin Dai +8 more
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The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas
Frontiers in Endocrinology, 2021 Human pituitary adenomas are one of the most common intracranial neoplasms. Although most of these tumors are benign and can be treated medically or by transsphenoidal surgery, a subset of these tumors are fast-growing, aggressive, recur, and remain a ...
Zhiyu Xi +10 more
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Expressions of Cushing’s syndrome in multiple endocrine neoplasia type 1
Frontiers in Endocrinology, 2023 Cushing’s syndrome (CS) resulting from endogenous hypercortisolism can be sporadic or can occur in the context of familial disease because of pituitary or extra-pituitary neuroendocrine tumors.
William F. Simonds
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