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Orthotopic pituitary tumors generated by stereotaxic GC cell injection in immunocompetent rats [PDF]

Acta Neuropathologica Communications
Innovative treatment strategies for pituitary tumors are necessary to limit the disease burden and to improve survival in cases of carcinomas. The paucity and inaccuracy of available preclinical models substantially hamper pituitary research and drug ...
Etienne Lefevre, Fanny Chasseloup, Nataly Ladurelle, Clément Janot, Jean Laurent Thibaud, Isabelle Beau, Clovis Adam, Céline des Courtils, Philippe Zizzari, Alexandre Carpentier, Peter Kamenický   +10 more
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PIT-1/SF-1-positive pituitary tumors in patients with acromegaly: transcriptomic perspective [PDF]

Acta Neuropathologica Communications
Neuroendocrine pituitary tumors (PitNETs) are classified based on clinical manifestation and expression of pituitary cell lineage-specific transcription factors (TFs) and hormones.
Julia Rymuza, Qilin Zhang, Mateusz Bujko
doaj   +2 more sources

Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors

Frontiers in Endocrinology, 2022
Since Costello et al. proposed the concept of pseudocapsule of pituitary neuroendocrine tumors (PitNETs) in 1936, many studies have been published on its occurrence, development process, histopathology, and morphology.
Xiao Bin Wang, Tian Yi Han, Jian Gong Ma, Cheng He, Li Xue, Xun Zhang, Zhe Bao Wu   +6 more
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Sprouting Angiogenesis in Human Pituitary Adenomas

Frontiers in Oncology, 2022
IntroductionAngiogenesis in pituitary tumors is not fully understood, and a better understanding could help inform new pharmacologic therapies, particularly for aggressive pituitary tumors.Materials and Methods219 human pituitary tumors and 12 normal ...
Jie Zhou, Yaomin Hu, Wende Zhu, Chuansheng Nie, Wenxiu Zhao, Alexander T. Faje, Kay E. Labelle, Brooke Swearingen, Hang Lee, E. Tessa Hedley-Whyte, Xun Zhang, Pamela S. Jones, Karen K. Miller, Anne Klibanski, Yunli Zhou, Roy J. Soberman   +15 more
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Costs and Its Determinants in Pituitary Tumour Surgery

Frontiers in Endocrinology, 2022
PurposeValue-based healthcare (VBHC) provides a framework to improve care by improving patient outcomes and reducing healthcare costs. To support value-based decision making in clinical practice we evaluated healthcare costs and cost drivers in ...
Alies J. Dekkers, Alies J. Dekkers, Friso de Vries, Friso de Vries, Amir H. Zamanipoor Najafabadi, Emmy M. van der Hoeven, Marco J. T. Verstegen, Marco J. T. Verstegen, Alberto M. Pereira, Alberto M. Pereira, Alberto M. Pereira, Wouter R. van Furth, Wouter R. van Furth, Nienke R. Biermasz, Nienke R. Biermasz   +14 more
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How to Classify and Define Pituitary Tumors: Recent Advances and Current Controversies

Frontiers in Endocrinology, 2021
Pituitary tumors are very complex and heterogeneous and have a very wide range of proliferative and aggressive behaviors, and how to define and classify these tumors remains controversial.
Congxin Dai, Jun Kang, Xiaohai Liu, Yong Yao, Yong Yao, Haijun Wang, Haijun Wang, Renzhi Wang, Renzhi Wang   +8 more
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The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas

Frontiers in Endocrinology, 2021
Human pituitary adenomas are one of the most common intracranial neoplasms. Although most of these tumors are benign and can be treated medically or by transsphenoidal surgery, a subset of these tumors are fast-growing, aggressive, recur, and remain a ...
Zhiyu Xi, Pamela S. Jones, Masaaki Mikamoto, Xiaobin Jiang, Alexander T. Faje, Chuansheng Nie, Kathryn E. Labelle, Yunli Zhou, Karen K. Miller, Roy J. Soberman, Xun Zhang   +10 more
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Expressions of Cushing’s syndrome in multiple endocrine neoplasia type 1

Frontiers in Endocrinology, 2023
Cushing’s syndrome (CS) resulting from endogenous hypercortisolism can be sporadic or can occur in the context of familial disease because of pituitary or extra-pituitary neuroendocrine tumors.
William F. Simonds
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Pituitary blastoma, expanding the spectrum of newly recognized entities. A case report

Indian Journal of Pathology and Microbiology, 2022
Tumors of the pituitary gland and sellar region represent about 15% of all brain tumors, with pituitary adenoma being the commonest and pituitary carcinoma being very rare. Pituitary tumors in children are even rarer.
Meenakshi Swain, Sundaram Challa, Subodh Raju   +2 more
doaj   +1 more source

Cyclooxygenase enzyme and PGE2 expression in patients with functional and non-functional pituitary adenomas

BMC Endocrine Disorders, 2020
Background Pituitary adenomas as multifactorial intracranial neoplasms impose a massive burden of morbidity on patients and characterizing the molecular mechanism underlying their pathogenesis has received considerable attention.
Nasrin Akbari, Mohammad Ghorbani, Vahid Salimi, Alimohammad Alimohammadi, Mohammad E. Khamseh, Hamideh Akbari, Mitra Nourbakhsh, Alireza Sheikhi, S. Fahimeh Taghavi, Masoumeh Tavakoli-Yaraki   +9 more
doaj   +1 more source