Results 21 to 30 of about 52,796 (199)

Semi-supervised method for image texture classification of pituitary tumors via CycleGAN and optimized feature extraction

open access: yesBMC Medical Informatics and Decision Making, 2020
Background Accurately determining the softness level of pituitary tumors preoperatively by using their image textures can provide a basis for surgical options and prognosis.
Hong Zhu   +3 more
doaj   +1 more source

Up-regulation of sex-determining region Y-box 9 (SOX9) in growth hormone-secreting pituitary adenomas

open access: yesBMC Endocrine Disorders, 2021
Background Pituitary adenomas are benign brain tumors that cause considerable morbidity and neurological symptoms. SOX9 as a regulatory transcriptional mediator affects normal and tumor cell growth with an undefined role in pituitary adenomas ...
Farzad Izak Shirian   +8 more
doaj   +1 more source

Genetically engineered mouse models of pituitary tumors

open access: yesFrontiers in Oncology, 2014
Animal models constitute valuable tools for investigating the pathogenesis of cancer as well as for preclinical testing of novel therapeutics approaches.
David A Cano   +4 more
doaj   +1 more source

Components of the canonical and non-canonical Wnt pathways are not mis-expressed in pituitary tumors. [PDF]

open access: yesPLoS ONE, 2013
IntroductionCanonical and non-canonical Wnt pathways are involved in the genesis of multiple tumors; however, their role in pituitary tumorigenesis is mostly unknown.ObjectiveThis study evaluated gene and protein expression of Wnt pathways in pituitary ...
Leandro Machado Colli   +7 more
doaj   +1 more source

Pituitary Tumors [PDF]

open access: yesEndocrinology and Metabolism Clinics of North America, 2015
Pituitary tumors are commonly encountered intracranial neoplasms that are invariably benign. Classic oncogene mutations are not encountered in these tumors, and disrupted cell cycle control and growth factor signaling likely contribute to pathogenesis and natural history.
openaire   +2 more sources

Pituitary tumors in patients with MEN1 syndrome

open access: yesClinics, 2012
We briefly review the characteristics of pituitary tumors associated with multiple endocrine neoplasia type 1. Multiple endocrine neoplasia type 1 is an autosomal-dominant disorder most commonly characterized by tumors of the pituitary, parathyroid ...
Luis V. Syro   +8 more
doaj   +1 more source

Role of microRNA in oncogenesis of pituitary tumors and their practical significance [PDF]

open access: yesТерапевтический архив, 2016
Microribonucleic acids (miRNAs) are a class of noncoding RNAs that regulate posttranscriptional gene expression. These molecules are regulators of cell proliferation, metabolism, apoptosis, and differentiation.
A M Lapshina   +4 more
doaj   +1 more source

Anti-VEGF Therapy in Refractory Pituitary Adenomas and Pituitary Carcinomas: A Review

open access: yesFrontiers in Oncology, 2021
Most pituitary tumors are considered benign adenomas, and only 0.1%–0.2% of them present metastasis and are defined as pituitary carcinomas (PCs). Refractory pituitary adenomas (PAs) lie between benign adenomas and true malignant PCs and are defined as ...
Congxin Dai   +4 more
doaj   +1 more source

Tumor of the Pituitary Body [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1899
n ...
Walton, G. L.   +2 more
openaire   +2 more sources

Experimental Evidence and Clinical Implications of Pituitary Adenoma Stem Cells

open access: yesFrontiers in Endocrinology, 2020
Pituitary adenomas, accounting for 15% of diagnosed intracranial neoplasms, are usually benign and pharmacologically and surgically treatable; however, the critical location, mass effects and hormone hypersecretion sustain their significant morbidity ...
Roberto Würth   +5 more
doaj   +1 more source

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