Results 41 to 50 of about 110,519 (362)

Anti-VEGF Therapy in Refractory Pituitary Adenomas and Pituitary Carcinomas: A Review

Frontiers in Oncology, 2021
Most pituitary tumors are considered benign adenomas, and only 0.1%–0.2% of them present metastasis and are defined as pituitary carcinomas (PCs). Refractory pituitary adenomas (PAs) lie between benign adenomas and true malignant PCs and are defined as ...
Congxin Dai, Siyu Liang, Bowen Sun, Yong Li, Jun Kang   +4 more
doaj   +1 more source

Management of pituitary spindle cell oncocytomas: A case report and review of the literature

Interdisciplinary Neurosurgery, 2021
Pituitary spindle cell oncocytomas represent a rare pathologic entity within the differential diagnosis for pituitary tumors. As part of a class of tumors that includes low grade non-endocrine pituitary tumors such as pituicytomas and granular cell ...
Hael Abdulrazeq, Matthew Anderson, Jonathan Poggi, Shailen Sampath, Colin Kanach, Ivana Dellale, Prakash Sampath   +6 more
doaj   +1 more source

Experimental Evidence and Clinical Implications of Pituitary Adenoma Stem Cells

Frontiers in Endocrinology, 2020
Pituitary adenomas, accounting for 15% of diagnosed intracranial neoplasms, are usually benign and pharmacologically and surgically treatable; however, the critical location, mass effects and hormone hypersecretion sustain their significant morbidity ...
Roberto Würth, Stefano Thellung, Alessandro Corsaro, Federica Barbieri, Tullio Florio, Tullio Florio   +5 more
doaj   +1 more source

Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion [PDF]

, 1989
We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis.
A Chatelain, AC Hale, B Allolio, B. Allolio, H Imura, JL Doppmann, JW Findling, K Nakao, M Reincke, M Reincke, M Thoren, M. Reincke, PJ Fuller, RC Pedersen, RE Mains, RS Yalow, SJ Ratter, U. Deuß, W. Winkelmann, Y Yamada   +19 more
core   +1 more source

Thyrotropin-secreting pituitary tumors [PDF]

Endocrine Reviews, 1996
I. Introduction The term “TSH-secreting pituitary tumors” includes two opposite clinical conditions: true thyrotroph neoplasia that results in secondary hyperthyroidism, also called “central hyperthyroidism,” and pituitary hyperplasia resulting from longstanding primary hypothyroidism. The latter condition was first recognized 145 yr ago (1), while the
P. Beck-Peccoz, F. Brucker Davis, L. Persani, R. C. Smallridge, B. D. Weintraub   +4 more
openaire   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

An efficient deep learning model for brain tumour detection with privacy preservation

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Internet of medical things (IoMT) is becoming more prevalent in healthcare applications as a result of current AI advancements, helping to improve our quality of life and ensure a sustainable health system. IoMT systems with cutting‐edge scientific capabilities are capable of detecting, transmitting, learning and reasoning.
Mujeeb Ur Rehman, Arslan Shafique, Imdad Ullah Khan, Yazeed Yasin Ghadi, Jawad Ahmad, Mohammed S. Alshehri, Mimonah Al Qathrady, Majed Alhaisoni, Muhammad H. Zayyan   +8 more
wiley   +1 more source

Pediatric pituitary neuroendocrine tumors–a 13-year experience in a tertiary center

Frontiers in Oncology, 2023
IntroductionPediatric pituitary neuroendocrine tumor is a rare condition, and despite previous research focusing on this specific group, the main factors influencing the surgical cure rate have not been identified.MethodsWe conducted a single-center ...
Xiaoxu Li, Kan Deng, Yi Zhang, Ming Feng, Bing Xing, Wei Lian, Yong Yao   +6 more
doaj   +1 more source