Sellar plasmacytoma with massive bleeding during surgery
Plasmacytoma in the sellar region is an extremely rare occurrence. Sellar plasmacytoma is often difficult to differentiate from pituitary tumors both clinically and radiologically.
Dong Hoon Lee+4 more
doaj +1 more source
Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors
The molecular mechanisms leading to aryl hydrocarbon receptor interacting protein (AIP) mutation-induced aggressive, young-onset growth hormone-secreting pituitary tumors are not fully understood.
Sayka Barry+15 more
semanticscholar +1 more source
Components of the canonical and non-canonical Wnt pathways are not mis-expressed in pituitary tumors. [PDF]
IntroductionCanonical and non-canonical Wnt pathways are involved in the genesis of multiple tumors; however, their role in pituitary tumorigenesis is mostly unknown.ObjectiveThis study evaluated gene and protein expression of Wnt pathways in pituitary ...
Leandro Machado Colli+7 more
doaj +1 more source
How to Classify Pituitary Neuroendocrine Tumors (PitNET)s in 2020
Adenohypophyseal tumors, which were recently renamed pituitary neuroendocrine tumors (PitNET), are mostly benign, but may present various behaviors: invasive, “aggressive” and malignant with metastases.
J. Trouillas+5 more
semanticscholar +1 more source
Pituitary metastasis of small cell lung cancer: Two case reports
Pituitary metastasis is a rare manifestation of systemic malignancy accounting for approximately 1% of all pituitary tumors. Breast and lung tumors are the most common primary sources of metastases, yet other sites such as the gastrointestinal tract ...
Beatriz Martinez Quintero+4 more
doaj +1 more source
The Microenvironment of Pituitary Tumors—Biological and Therapeutic Implications
The tumor microenvironment (TME) includes resident and infiltrative non-tumor cells, as well as blood and lymph vessels, extracellular matrix molecules, and numerous soluble factors, such as cytokines and chemokines. While the TME is now considered to be
M. Ilie+3 more
semanticscholar +1 more source
Pituitary tumors in patients with MEN1 syndrome
We briefly review the characteristics of pituitary tumors associated with multiple endocrine neoplasia type 1. Multiple endocrine neoplasia type 1 is an autosomal-dominant disorder most commonly characterized by tumors of the pituitary, parathyroid ...
Luis V. Syro+8 more
doaj +1 more source
Management of pituitary spindle cell oncocytomas: A case report and review of the literature
Pituitary spindle cell oncocytomas represent a rare pathologic entity within the differential diagnosis for pituitary tumors. As part of a class of tumors that includes low grade non-endocrine pituitary tumors such as pituicytomas and granular cell ...
Hael Abdulrazeq+6 more
doaj +1 more source
Anti-VEGF Therapy in Refractory Pituitary Adenomas and Pituitary Carcinomas: A Review
Most pituitary tumors are considered benign adenomas, and only 0.1%–0.2% of them present metastasis and are defined as pituitary carcinomas (PCs). Refractory pituitary adenomas (PAs) lie between benign adenomas and true malignant PCs and are defined as ...
Congxin Dai+4 more
doaj +1 more source
Experimental Evidence and Clinical Implications of Pituitary Adenoma Stem Cells
Pituitary adenomas, accounting for 15% of diagnosed intracranial neoplasms, are usually benign and pharmacologically and surgically treatable; however, the critical location, mass effects and hormone hypersecretion sustain their significant morbidity ...
Roberto Würth+5 more
doaj +1 more source