Results 41 to 50 of about 3,128,159 (361)
Endocrinology and Metabolism Clinics of North America, 2015 Pituitary tumors are commonly encountered intracranial neoplasms that are invariably benign. Classic oncogene mutations are not encountered in these tumors, and disrupted cell cycle control and growth factor signaling likely contribute to pathogenesis and natural history.
openaire +2 more sources
Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors
Oncogene, 2019 The molecular mechanisms leading to aryl hydrocarbon receptor interacting protein (AIP) mutation-induced aggressive, young-onset growth hormone-secreting pituitary tumors are not fully understood.
Sayka Barry +15 more
semanticscholar +1 more source
BMC Endocrine Disorders, 2021 Background Pituitary adenomas are benign brain tumors that cause considerable morbidity and neurological symptoms. SOX9 as a regulatory transcriptional mediator affects normal and tumor cell growth with an undefined role in pituitary adenomas ...
Farzad Izak Shirian +8 more
doaj +1 more source
How to Classify Pituitary Neuroendocrine Tumors (PitNET)s in 2020
Cancers, 2020 Adenohypophyseal tumors, which were recently renamed pituitary neuroendocrine tumors (PitNET), are mostly benign, but may present various behaviors: invasive, “aggressive” and malignant with metastases.
J. Trouillas +5 more
semanticscholar +1 more source
The Microenvironment of Pituitary Tumors—Biological and Therapeutic Implications
Cancers, 2019 The tumor microenvironment (TME) includes resident and infiltrative non-tumor cells, as well as blood and lymph vessels, extracellular matrix molecules, and numerous soluble factors, such as cytokines and chemokines. While the TME is now considered to be
M. Ilie +3 more
semanticscholar +1 more source
Components of the canonical and non-canonical Wnt pathways are not mis-expressed in pituitary tumors. [PDF]
PLoS ONE, 2013 IntroductionCanonical and non-canonical Wnt pathways are involved in the genesis of multiple tumors; however, their role in pituitary tumorigenesis is mostly unknown.ObjectiveThis study evaluated gene and protein expression of Wnt pathways in pituitary ...
Leandro Machado Colli +7 more
doaj +1 more source
Pituitary metastasis of small cell lung cancer: Two case reports
Journal of Clinical and Translational Endocrinology Case Reports, 2021 Pituitary metastasis is a rare manifestation of systemic malignancy accounting for approximately 1% of all pituitary tumors. Breast and lung tumors are the most common primary sources of metastases, yet other sites such as the gastrointestinal tract ...
Beatriz Martinez Quintero +4 more
doaj +1 more source
Pituitary tumors in patients with MEN1 syndrome
Clinics, 2012 We briefly review the characteristics of pituitary tumors associated with multiple endocrine neoplasia type 1. Multiple endocrine neoplasia type 1 is an autosomal-dominant disorder most commonly characterized by tumors of the pituitary, parathyroid ...
Luis V. Syro +8 more
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Sellar plasmacytoma with massive bleeding during surgery
Cancer Treatment and Research Communications, 2022 Plasmacytoma in the sellar region is an extremely rare occurrence. Sellar plasmacytoma is often difficult to differentiate from pituitary tumors both clinically and radiologically.
Dong Hoon Lee +4 more
doaj +1 more source