Experimental Evidence and Clinical Implications of Pituitary Adenoma Stem Cells
Frontiers in Endocrinology, 2020 Pituitary adenomas, accounting for 15% of diagnosed intracranial neoplasms, are usually benign and pharmacologically and surgically treatable; however, the critical location, mass effects and hormone hypersecretion sustain their significant morbidity ...
Roberto Würth +5 more
doaj +1 more source
Examining the behaviour of state-of-the-art convolutional neural networks for brain tumor detection with and without transfer learning [PDF]
arXiv, 2022 Distinguishing normal from malignant and determining the tumor type are critical components of brain tumor diagnosis. Two different kinds of dataset are investigated using state-of-the-art CNN models in this research work. One dataset(binary) has images of normal and tumor types, while another(multi-class) provides all images of tumors classified as ...
arxiv
The pituitary TGFb1 system as a novel target for the treatment of resistant prolactinomas [PDF]
, 2016 Prolactinomas are the most frequently observed pituitary adenomas and most of themrespond well to conventional treatment with dopamine agonists (DAs).
Camilletti, María Andrea +3 more
core +2 more sources
Pediatric pituitary neuroendocrine tumors–a 13-year experience in a tertiary center
Frontiers in Oncology, 2023 IntroductionPediatric pituitary neuroendocrine tumor is a rare condition, and despite previous research focusing on this specific group, the main factors influencing the surgical cure rate have not been identified.MethodsWe conducted a single-center ...
Xiaoxu Li +6 more
doaj +1 more source
Brain tumor multi classification and segmentation in MRI images using deep learning [PDF]
arXiv, 2023 This study proposes a deep learning model for the classification and segmentation of brain tumors from magnetic resonance imaging (MRI) scans. The classification model is based on the EfficientNetB1 architecture and is trained to classify images into four classes: meningioma, glioma, pituitary adenoma, and no tumor.
arxiv
Mutation analysis of inhibitory guanine nucleotide binding protein alpha (GNAI) loci in young and familial pituitary adenomas. [PDF]
PLoS ONE, 2014 Pituitary adenomas are neoplasms of the anterior pituitary lobe and account for 15-20% of all intracranial tumors. Although most pituitary tumors are benign they can cause severe symptoms related to tumor size as well as hypopituitarism and/or ...
Hande Demir +6 more
doaj +1 more source
Preoperative Volume Determination for Pituitary Adenoma [PDF]
, 2016 The most common sellar lesion is the pituitary adenoma, and sellar tumors are approximately 10-15% of all intracranial neoplasms. Manual slice-by-slice segmentation takes quite some time that can be reduced by using the appropriate algorithms. In this contribution, we present a segmentation method for pituitary adenoma.
arxiv +1 more source
Molecular Oncology, EarlyView.The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits +7 more
wiley +1 more source
Incident Angle Study for Designing an Endoscopic Tool for Intraoperative Brain Tumor Detection [PDF]
arXiv, 2023 In neurosurgical procedures maximizing the resection of tumor tissue while avoiding healthy tissue is of paramount importance and a difficult task due to many factors, such as surrounding eloquent brain. Swiftly identifying tumor tissue for removal could increase surgical outcomes.
arxiv
Loss-of-function mutations in the CABLES1 gene are a novel cause of Cushing's disease. [PDF]
, 2017 The CABLES1 cell cycle regulator participates in the adrenal-pituitary negative feedback, and its expression is reduced in corticotropinomas, pituitary tumors with a largely unexplained genetic basis.
Assié, Guillaume +20 more
core +2 more sources