Results 61 to 70 of about 3,206,200 (405)

Evaluation of the expression of necroptosis pathway mediators and its association with tumor characteristics in functional and non-functional pituitary adenomas

BMC Endocrine Disorders, 2022
Background Pituitary adenomas impose a burden of morbidity on patients and characterizing the molecular mechanisms underlying its pathogenesis received remarkable attention.
Mohammad E. Khamseh, Alireza Sheikhi, Zahra Shahsavari, Mohammad Ghorbani, Hamideh Akbari, Mehrnaz Imani, Mahshid Panahi, Alimohammad Alimohammadi, Maryam Ameri, Shima Nazem, Vahid Salimi, Masoumeh Tavakoli-Yaraki   +11 more
doaj   +1 more source

The clinical characteristics and gene mutations associated with thyroid hormone resistance syndrome coexisting with pituitary tumors

Frontiers in Endocrinology, 2023
AimsResistance to thyroid hormone (RTH) and pituitary tumors are both rare diseases, and the differential diagnosis of these two diseases is difficult in some cases. There are also patients who have both conditions, making diagnosis more difficult.
Junyu Zhao, Lusi Xu, Chunyu Li, Fei Wang, Lin Liao, Jianjun Dong   +5 more
doaj   +1 more source

Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]

, 2016
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia, Lara, H. E., Recabarren, S. E., Roselli, C. E., Zubeldia Brenner, Lautaro   +4 more
core   +2 more sources

Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/β-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors

Cellular Physiology and Biochemistry, 2018
Background/Aims: Long noncoding RNAs (lncRNAs) are critical regulators in various diseases including human cancer and could function as competing endogenous RNAs (ceRNAs) to regulate microRNAs (miRNAs).
Heyuan Wang, Guixia Wang, Yufei Gao, Cong-hai Zhao, Xiao-ping Li, Fuqiang Zhang, Chunyan Jiang, Bing Wu   +7 more
semanticscholar   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source

Role of microRNA in oncogenesis of pituitary tumors and their practical significance [PDF]

Терапевтический архив, 2016
Microribonucleic acids (miRNAs) are a class of noncoding RNAs that regulate posttranscriptional gene expression. These molecules are regulators of cell proliferation, metabolism, apoptosis, and differentiation.
A M Lapshina, P M Khandaeva, Zh E Belaya, L Ya Rozhinskaya, G A Melnichenko   +4 more
doaj   +1 more source

Does an Analysis of the Pulsatile Secretion Pattern of Adrenocorticotropin and Cortisol Predict the Result of Transsphenoidal Surgery in Cushing’s Disease. [PDF]

, 1993
The endocrinological, surgical, and histological findings of patients with ACTH-dependent Cushing's disease were correlated with the pulsatile secretion pattern of ACTH and cortisol and the outcome after transsphenoidal pituitary surgery.
Brabant, Georg, Buchfelder, Michael, Fahlbusch, Rudolf, Müller, Otto A., Stalla, Günter K., Wentzlaff-Eggebert, Holger   +5 more
core   +1 more source

Biological and Therapeutic Implications of the Tumor Microenvironment in Pituitary Adenomas [PDF]

, 2022
Mirela Diana Ilie, Alexandre Vasiljevic, Philippe Bertolino, Gérald Raverot   +3 more
openalex   +1 more source

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

Drp1‐Mediated Mitochondrial Metabolic Dysfunction Inhibits the Tumor Growth of Pituitary Adenomas [PDF]

, 2022
Kexia Fan, Xiao Ding, Zhenle Zang, Yin Zhang, Xiaoshuang Tang, Xiangdong Pei, Qingbo Chen, Huachun Yin, Xin Zheng, Yong Chen, Song Li, Hui Yang   +11 more
openalex   +1 more source